iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Csv-026121

UUCD1 version

UUC-CiS-00379

Ensembl Protein ID

ENSCSAVP00000003217.1

UniProt Accession

H2YD19; H2YD19_CIOSA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAVG00000001912.1	ENSCSAVT00000003266.1	ENSCSAVP00000003217.1
ENSCSAVG00000001912.1	ENSCSAVT00000003267.1	ENSCSAVP00000003218.1
ENSCSAVG00000001912.1	ENSCSAVT00000003268.1	ENSCSAVP00000003219.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.90e-87	293.7	1346	1730

Active Site

Position(s)	Description	Evidence
1698	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 5    lkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlq...pnpdsglknp..................ehlk 69
            ++ lev+++gE g++l G+t+ef++l+s+e+q++dlgl++ +en++++++     ++s++++p                  +  +
   Q: 1346 TRSLLEVQYEGEVGTGL-GPTLEFYTLVSHEMQRSDLGLWRSDENSNSQFNapvAMETSFVHSPvglyplpigrtsklgpiaKACS 1430
           567899***********.**********************888885554441104556666666********************** PP
   S: 70   lFeflGrllgkalqdgrlldlplsksfyklllgk..klsledleevdpelykslkeikenaes....................... 130
            F+flGrl +ka++dgrlld+pls  +yk l+++  ++++ dle+vdp +  + +++k++ ++                       
   Q: 1431 KFRFLGRLFAKAVMDGRLLDVPLSMICYKWLVNQenSITWLDLEQVDPGMSLTFNKLKRLLHQrllieqdgtpsllhcqdgaqeri 1516
           *********************************966699**********9999999998873344444555555666665554444 PP
   S: 131  .dieelgldltfsvseei.....lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFt 210
             i     ++  ++ e++     l+   + eL+  G++++ t+eN+++Y +l+++++l+eg+++q++a+r+Gf++v+pl+ +++F 
   Q: 1517 nAI-----TMDGCRLEDLgldflLPGFPNIELMKFGAKTSLTIENLDKYLSLIAHWTLNEGVRQQLDAMRDGFQSVFPLQAIDYFY 1597
           422.....33333333334455599************************************************************* PP
   S: 211  eeelellicGe..eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk... 291
           +eel++l cG   + ++  +l++ ++ ++gy+++s+a++++++vl++ ++ e++afLqFvTgs+ lP+gG+++l+p l+v+rk   
   Q: 1598 PEELDQLFCGAryQPWSERELTDSCRTDHGYSHESEAVKTLFRVLSQYDAAEQRAFLQFVTGSPHLPVGGLRALHPPLTVVRKtcd 1683
           **********977889999999999************************************************************* PP
   S: 292  ..dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
              +sd+ lPs++TC+nyLkLPeYs++++++e+L  A +e+ k+F l
   Q: 1684 enTSSDSYLPSVMTCVNYLKLPEYSNENVMRERLHKAAQEGqKSFLL 1730
           988888***********************************999976 PP

Organism

Ciona savignyi

Protein Sequence
(Fasta)

RKRYQSPPNH PLYARKAATN ASKTGSCAST SRRGRGKTSS VNSRELEDPA PAAMSQEADQ 60
SADENQPGAV GSNTGENQGA SENPDGELDE PDMSRLQALL EARGLPSHFF GTLGPRVQQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAAACGAT ATCAGTCGCC TCCCAACCAT CCACTGTACG CAAGAAAAGC AGCAACCAAC 60
GCCAGCAAGA CGGGGTCTTG TGCCAGCACA AGGTAAAGTT AGTTATCATT TTGAAGTCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000060	Aegilops tauschii	33.56	3.00e-103	369.00
IUUC-Aml-001502	Ailuropoda melanoleuca	50.38	0.00e+00	1480.00
IUUC-Atr-002821	Amborella trichopoda	32.44	1.00e-95	343.00
IUUC-Apl-003531	Anas platyrhynchos	48.73	0.00e+00	1436.00
IUUC-Aly-005962	Arabidopsis lyrata	36.05	1.00e-100	360.00
IUUC-Ath-006636	Arabidopsis thaliana	36.21	1.00e-102	367.00
IUUC-Ago-007875	Ashbya gossypii	33.40	2.00e-72	266.00
IUUC-Acl-008242	Aspergillus clavatus	36.68	1.00e-98	353.00
IUUC-Afl-008736	Aspergillus flavus	37.67	1.00e-97	350.00
IUUC-Afu-008812	Aspergillus fumigatus	34.22	5.00e-101	361.00
IUUC-Ani-009407	Aspergillus nidulans	33.86	2.00e-95	343.00
IUUC-Ang-009763	Aspergillus niger	34.88	1.00e-88	320.00
IUUC-Aor-009941	Aspergillus oryzae	30.00	1.00e-102	367.00
IUUC-Ate-010459	Aspergillus terreus	33.20	3.00e-75	275.00
IUUC-Ame-011761	Astyanax mexicanus	48.51	0.00e+00	1497.00
IUUC-Bgr-012265	Blumeria graminis	37.43	7.00e-94	338.00
IUUC-Bta-013070	Bos taurus	50.21	0.00e+00	1489.00
IUUC-Bci-013890	Botrytis cinerea	37.52	1.00e-96	347.00
IUUC-Bdi-014961	Brachypodium distachyon	32.97	4.00e-101	362.00
IUUC-Bol-015942	Brassica oleracea	35.99	4.00e-100	358.00
IUUC-Bra-016849	Brassica rapa	35.99	8.00e-100	357.00
IUUC-Cja-019046	Callithrix jacchus	49.30	0.00e+00	1488.00
IUUC-Cfa-020521	Canis familiaris	50.27	0.00e+00	1468.00
IUUC-Cpo-021639	Cavia porcellus	47.65	0.00e+00	1400.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	38.07	4.00e-90	323.00
IUUC-Csa-023231	Chlorocebus sabaeus	48.92	0.00e+00	1482.00
IUUC-Cho-024380	Choloepus hoffmanni	55.04	7.00e-133	468.00
IUUC-Cin-025482	Ciona intestinalis	83.67	0.00e+00	932.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	38.68	3.00e-104	372.00
IUUC-Cne-026857	Cryptococcus neoformans	35.70	2.00e-82	300.00
IUUC-Cme-027226	Cyanidioschyzon merolae	32.10	1.00e-67	250.00
IUUC-Dre-028174	Danio rerio	47.72	0.00e+00	1460.00
IUUC-Dor-030939	Dipodomys ordii	46.72	0.00e+00	656.00
IUUC-Dse-031444	Dothistroma septosporum	32.21	5.00e-96	345.00
IUUC-Dme-032162	Drosophila melanogaster	56.50	9.00e-134	471.00
IUUC-Ete-032345	Echinops telfairi	43.18	0.00e+00	963.00
IUUC-Eca-033229	Equus caballus	50.27	0.00e+00	1463.00
IUUC-Eeu-035205	Erinaceus europaeus	48.62	0.00e+00	793.00
IUUC-Fca-036444	Felis catus	49.91	0.00e+00	1468.00
IUUC-Fal-037131	Ficedula albicollis	49.05	0.00e+00	1481.00
IUUC-Fox-038035	Fusarium oxysporum	34.95	2.00e-104	371.00
IUUC-Fso-038320	Fusarium solani	34.54	2.00e-103	370.00
IUUC-Gmo-039497	Gadus morhua	48.45	0.00e+00	1486.00
IUUC-Ggr-040057	Gaeumannomyces graminis	39.46	2.00e-102	366.00
IUUC-Gga-041021	Gallus gallus	49.22	0.00e+00	1488.00
IUUC-Gac-042474	Gasterosteus aculeatus	48.61	0.00e+00	1476.00
IUUC-Gma-043060	Glycine max	32.31	2.00e-98	353.00
IUUC-Ggo-044855	Gorilla gorilla	49.36	0.00e+00	1487.00
IUUC-Hsa-046147	Homo sapiens	49.61	0.00e+00	1498.00
IUUC-Hvu-047811	Hordeum vulgare	35.56	3.00e-104	372.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	47.16	0.00e+00	846.00
IUUC-Kpa-049098	Komagataella pastoris	36.89	3.00e-83	302.00
IUUC-Lch-049818	Latimeria chalumnae	48.41	0.00e+00	1447.00
IUUC-Lpe-051017	Leersia perrieri	33.74	2.00e-100	360.00
IUUC-Loc-051777	Lepisosteus oculatus	48.12	0.00e+00	1503.00
IUUC-Lma-052990	Leptosphaeria maculans	34.60	8.00e-103	367.00
IUUC-Laf-053727	Loxodonta africana	47.13	0.00e+00	847.00
IUUC-Mcc-055799	Macaca mulatta	48.92	0.00e+00	1481.00
IUUC-Meu-056065	Macropus eugenii	45.85	0.00e+00	759.00
IUUC-Mor-057054	Magnaporthe oryzae	39.85	3.00e-105	375.00
IUUC-Mpo-057417	Magnaporthe poae	39.61	1.00e-102	367.00
IUUC-Mtr-057849	Medicago truncatula	37.18	6.00e-99	354.00
IUUC-Mla-058870	Melampsora laricipopulina	36.86	3.00e-93	335.00
IUUC-Mga-059580	Meleagris gallopavo	48.54	0.00e+00	1202.00
IUUC-Mvi-060507	Microbotryum violaceum	36.50	9.00e-97	347.00
IUUC-Mmr-060816	Microcebus murinus	46.88	0.00e+00	842.00
IUUC-Mdo-062866	Monodelphis domestica	45.88	0.00e+00	762.00
IUUC-Mmu-063906	Mus musculus	48.21	0.00e+00	1466.00
IUUC-Mac-065046	Musa acuminata	38.43	3.00e-98	352.00
IUUC-Mpu-066199	Mustela putorius furo	47.23	0.00e+00	850.00
IUUC-Mlu-067110	Myotis lucifugus	49.41	0.00e+00	1449.00
IUUC-Nfi-068482	Neosartorya fischeri	34.33	1.00e-102	367.00
IUUC-Ncr-068906	Neurospora crassa	37.52	5.00e-102	365.00
IUUC-Nle-069410	Nomascus leucogenys	49.19	0.00e+00	1471.00
IUUC-Opr-070401	Ochotona princeps	44.06	4.00e-132	465.00
IUUC-Ont-072100	Oreochromis niloticus	48.10	0.00e+00	1469.00
IUUC-Oan-073121	Ornithorhynchus anatinus	49.16	0.00e+00	1508.00
IUUC-Ocu-074623	Oryctolagus cuniculus	48.67	0.00e+00	1477.00
IUUC-Oba-075380	Oryza barthii	29.21	4.00e-102	365.00
IUUC-Obr-076915	Oryza brachyantha	33.70	2.00e-103	369.00
IUUC-Ogl-076926	Oryza glaberrima	29.21	7.00e-102	364.00
IUUC-Ogu-078892	Oryza glumaepatula	29.32	1.00e-102	366.00
IUUC-Oin-079256	Oryza indica	33.15	4.00e-99	355.00
IUUC-Olo-081086	Oryza longistaminata	29.47	1.00e-101	363.00
IUUC-Ome-081422	Oryza meridionalis	33.01	3.00e-99	355.00
IUUC-Oni-083047	Oryza nivara	29.32	4.00e-104	371.00
IUUC-Opu-083641	Oryza punctata	34.48	8.00e-99	353.00
IUUC-Oru-084439	Oryza rufipogon	29.32	1.00e-102	366.00
IUUC-Osa-085617	Oryza sativa	36.85	2.00e-99	354.00
IUUC-Ola-087173	Oryzias latipes	47.52	0.00e+00	1464.00
IUUC-Olu-087871	Ostreococcus lucimarinus	34.72	9.00e-84	302.00
IUUC-Oga-087908	Otolemur garnettii	47.23	0.00e+00	847.00
IUUC-Oar-090277	Ovis aries	49.91	0.00e+00	1483.00
IUUC-Ptr-091543	Pan troglodytes	49.36	0.00e+00	1500.00
IUUC-Pan-092243	Papio anubis	48.92	0.00e+00	1481.00
IUUC-Psi-093150	Pelodiscus sinensis	49.41	0.00e+00	1488.00
IUUC-Pno-094891	Phaeosphaeria nodorum	37.06	6.00e-102	364.00
IUUC-Ppa-095181	Physcomitrella patens	37.90	2.00e-99	355.00
IUUC-Pfo-096267	Poecilia formosa	47.61	0.00e+00	1478.00
IUUC-Pab-098072	Pongo abelii	49.66	0.00e+00	1492.00
IUUC-Pop-099190	Populus trichocarpa	37.34	5.00e-100	358.00
IUUC-Pca-100311	Procavia capensis	48.89	0.00e+00	831.00
IUUC-Ppe-101284	Prunus persica	36.35	1.00e-99	357.00
IUUC-Pva-102215	Pteropus vampyrus	63.68	4.00e-140	491.00
IUUC-Pgr-103694	Puccinia graminis	35.77	6.00e-94	338.00
IUUC-Ptt-103916	Puccinia triticina	35.21	2.00e-88	320.00
IUUC-Pte-104346	Pyrenophora teres	36.59	9.00e-101	360.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	36.78	7.00e-102	364.00
IUUC-Rno-105315	Rattus norvegicus	48.10	0.00e+00	1457.00
IUUC-Sce-106273	Saccharomyces cerevisiae	33.46	4.00e-70	258.00
IUUC-Sha-106835	Sarcophilus harrisii	46.93	0.00e+00	844.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	35.16	1.00e-89	323.00
IUUC-Spo-108081	Schizosaccharomyces pombe	36.45	3.00e-90	325.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	37.52	3.00e-99	355.00
IUUC-Smo-109590	Selaginella moellendorffii	38.27	1.00e-99	357.00
IUUC-Sit-110717	Setaria italica	32.46	3.00e-100	358.00
IUUC-Sly-111557	Solanum lycopersicum	33.70	4.00e-104	372.00
IUUC-Stu-112896	Solanum tuberosum	33.42	6.00e-94	337.00
IUUC-Sar-113224	Sorex araneus	61.14	4.00e-180	624.00
IUUC-Sbi-114313	Sorghum bicolor	34.11	2.00e-102	366.00
IUUC-Sre-114993	Sporisorium reilianum	31.00	2.00e-87	317.00
IUUC-Ssc-115535	Sus scrofa	47.04	0.00e+00	1377.00
IUUC-Tgu-117493	Taeniopygia guttata	57.98	0.00e+00	682.00
IUUC-Tru-118669	Takifugu rubripes	48.10	0.00e+00	1465.00
IUUC-Tsy-119373	Tarsius syrichta	43.48	0.00e+00	689.00
IUUC-Tni-120049	Tetraodon nigroviridis	44.62	6.00e-131	459.00
IUUC-Tca-121779	Theobroma cacao	32.22	4.00e-97	348.00
IUUC-Tre-122195	Trichoderma reesei	39.42	3.00e-100	359.00
IUUC-Tvi-122650	Trichoderma virens	38.36	9.00e-100	357.00
IUUC-Tae-123120	Triticum aestivum	33.43	8.00e-104	370.00
IUUC-Tur-126295	Triticum urartu	33.10	7.00e-101	361.00
IUUC-Tme-126964	Tuber melanosporum	37.76	2.00e-99	356.00
IUUC-Tbe-128149	Tupaia belangeri	59.60	1.00e-111	397.00
IUUC-Ttr-128165	Tursiops truncatus	49.76	0.00e+00	794.00
IUUC-Uma-129365	Ustilago maydis	35.14	1.00e-81	298.00
IUUC-Vda-129725	Verticillium dahliae	38.03	3.00e-101	362.00
IUUC-Vpa-130678	Vicugna pacos	47.09	0.00e+00	1184.00
IUUC-Vvi-131147	Vitis vinifera	32.45	2.00e-102	366.00
IUUC-Xtr-132636	Xenopus tropicalis	48.00	0.00e+00	1463.00
IUUC-Xma-133458	Xiphophorus maculatus	47.50	0.00e+00	1490.00
IUUC-Yli-134481	Yarrowia lipolytica	35.36	1.00e-84	306.00
IUUC-Zma-135657	Zea mays	32.46	1.00e-100	360.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence