iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000063870.12	ENSMUST00000112392.7	ENSMUSP00000108011.1
ENSMUSG00000063870.12	ENSMUST00000056889.14	ENSMUSP00000060054.8
ENSMUSG00000063870.12	ENSMUST00000112390.7	ENSMUSP00000108009.1
ENSMUSG00000063870.12	ENSMUST00000124317.1	ENSMUSP00000120704.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
circBase	miRTarBase	microRNA	TRANSFAC
RepTar	RAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
PhosphositePlus	PHOSIDA	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.60e-16	59.6	450	494

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C vC++gge    l++C+ C + +H +Cl+++  +e pn e w Cp+C+
   Q: 450  EFCRVCKDGGE----LLCCDTCPSSYHIHCLNPP-LPEIPNGE-WLCPRCT 494
           58*********....*******************.*******8.******6 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MASGLGSPSP CSAGSEEEDM DALLNNSLPP PHPENEEDPD EDLSEAETPK LKKKKKPKKP 60
RDPKIPKSKR QKKERLLLCR QLGDSSGEGP EFVEEEEEVA LRSDSEGSDY TPGKKKKKKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGCCAATG GTTGCCTGAG CGACGAGGGG GCGGGGGTTG CCCGGGAGAC CTAAAGAGGA 60
GGGTGGCGGT AGTGGAGGGG GGGGTTGGAG TTGGTTGAGG TTATTATGGG CTGTCCGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028725--CHD4
IPR012957--CHD_C2
IPR012958--CHD_N
IPR000953--Chromo/chromo_shadow_dom
IPR023780--Chromo_domain
IPR016197--Chromodomain-like
IPR002464--DNA/RNA_helicase_DEAH_CS
IPR009462--DUF1086
IPR009463--DUF1087
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50013--CHROMO_2
PS00690--DEAH_ATP_HELICASE
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF08074--CHDCT2
PF08073--CHDNT
PF00385--Chromo
PF06461--DUF1086
PF06465--DUF1087
PF00271--Helicase_C
PF00628--PHD
PF00176--SNF2_N

SMART

SM00298--CHROMO
SM00487--DEXDc
SM01146--DUF1086
SM01147--DUF1087
SM00490--HELICc
SM00249--PHD

Gene Ontology

GO:0016581--C:NuRD complex
GO:0005524--F:ATP binding
GO:0008026--F:ATP-dependent helicase activity
GO:0003677--F:DNA binding
GO:0008270--F:zinc ion binding
GO:0006325--P:chromatin organization
GO:0006355--P:regulation of transcription, DNA-templated
GO:0051225--P:spindle assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001361	Ailuropoda melanoleuca	95.77	0.00e+00	2959.00
IUUC-Apl-004175	Anas platyrhynchos	91.66	0.00e+00	2724.00
IUUC-Aca-004774	Anolis carolinensis	89.28	0.00e+00	2797.00
IUUC-Ame-011098	Astyanax mexicanus	81.33	0.00e+00	2378.00
IUUC-Bta-013220	Bos taurus	97.49	0.00e+00	2911.00
IUUC-Cel-018683	Caenorhabditis elegans	57.61	0.00e+00	1275.00
IUUC-Cja-019510	Callithrix jacchus	90.54	0.00e+00	2610.00
IUUC-Cfa-020422	Canis familiaris	98.12	0.00e+00	2933.00
IUUC-Cpo-021704	Cavia porcellus	98.04	0.00e+00	2895.00
IUUC-Csa-023625	Chlorocebus sabaeus	98.06	0.00e+00	2926.00
IUUC-Cho-024361	Choloepus hoffmanni	91.09	0.00e+00	1458.00
IUUC-Dre-027505	Danio rerio	79.01	0.00e+00	2456.00
IUUC-Dno-029656	Dasypus novemcinctus	97.54	0.00e+00	2904.00
IUUC-Dor-030354	Dipodomys ordii	96.00	0.00e+00	1899.00
IUUC-Eca-034112	Equus caballus	97.85	0.00e+00	2936.00
IUUC-Fca-036056	Felis catus	98.22	0.00e+00	2931.00
IUUC-Fal-037312	Ficedula albicollis	96.29	0.00e+00	2318.00
IUUC-Gga-040216	Gallus gallus	91.91	0.00e+00	2815.00
IUUC-Gac-042478	Gasterosteus aculeatus	77.59	0.00e+00	2016.00
IUUC-Ggo-044428	Gorilla gorilla	88.29	0.00e+00	2600.00
IUUC-Hsa-045908	Homo sapiens	95.92	0.00e+00	2936.00
IUUC-Itr-048002	Ictidomys tridecemlineatus	98.11	0.00e+00	2933.00
IUUC-Lch-049948	Latimeria chalumnae	78.03	0.00e+00	1915.00
IUUC-Loc-052144	Lepisosteus oculatus	85.18	0.00e+00	2114.00
IUUC-Mcc-055773	Macaca mulatta	96.18	0.00e+00	2918.00
IUUC-Mga-059633	Meleagris gallopavo	92.04	0.00e+00	2820.00
IUUC-Mmr-060886	Microcebus murinus	96.39	0.00e+00	2937.00
IUUC-Mdo-062872	Monodelphis domestica	94.88	0.00e+00	2598.00
IUUC-Mpu-066692	Mustela putorius furo	98.17	0.00e+00	2931.00
IUUC-Mlu-067785	Myotis lucifugus	98.12	0.00e+00	2924.00
IUUC-Nle-070039	Nomascus leucogenys	96.04	0.00e+00	2873.00
IUUC-Ont-072418	Oreochromis niloticus	82.57	0.00e+00	2117.00
IUUC-Ocu-074177	Oryctolagus cuniculus	95.18	0.00e+00	2925.00
IUUC-Ola-086880	Oryzias latipes	81.38	0.00e+00	2169.00
IUUC-Oga-088970	Otolemur garnettii	96.34	0.00e+00	2933.00
IUUC-Oar-090422	Ovis aries	97.83	0.00e+00	2865.00
IUUC-Pan-092441	Papio anubis	97.96	0.00e+00	2926.00
IUUC-Psi-093530	Pelodiscus sinensis	90.88	0.00e+00	2772.00
IUUC-Ppa-095213	Physcomitrella patens	42.04	0.00e+00	724.00
IUUC-Pfo-097530	Poecilia formosa	82.56	0.00e+00	2108.00
IUUC-Pab-097959	Pongo abelii	95.71	0.00e+00	2850.00
IUUC-Pva-103186	Pteropus vampyrus	96.36	0.00e+00	2849.00
IUUC-Rno-105692	Rattus norvegicus	98.12	0.00e+00	2909.00
IUUC-Ssc-115295	Sus scrofa	97.91	0.00e+00	2902.00
IUUC-Tgu-117484	Taeniopygia guttata	90.09	0.00e+00	2806.00
IUUC-Tru-118745	Takifugu rubripes	78.15	0.00e+00	2504.00
IUUC-Tsy-119261	Tarsius syrichta	85.67	0.00e+00	1998.00
IUUC-Tni-120764	Tetraodon nigroviridis	79.86	0.00e+00	2391.00
IUUC-Ttr-128478	Tursiops truncatus	92.13	0.00e+00	2699.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence