iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055020

Ensembl Protein ID

ENSMMUP00000006488.2

UniProt Accession

F7AN37; F7AN37_MACMU

Genbank Protein ID

AFH27874.1; EHH20253.1

Protein Name

GRB2-related adapter protein 2; Putative uncharacterized protein

Genbank Nucleotide ID

JSUE03005546; CM001262

Gene Name

GRAP2; EGK_03067

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000004880.3	ENSMMUT00000006896.3	ENSMMUP00000006488.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.60e-29	102.7	277	328

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++lyd+ea +ddeL +++G+vv+v+  ++ +  W+ g   l++k GlfP+n+v+ +
   Q: 277  RALYDFEALEDDELGFHSGEVVEVL--DSSNPSWWTG--RLHNKLGLFPANYVAPM 328
           79***********************..999*******..8*************875 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MEAVAKFDFT ASGEDELSFH TGDVLKILSN QEEWFKAELG SQEGYVPKNF IDIQFPEWFH 60
EGLSRHQAEN LLMGKEVGFF IIRASQSSPG DFSISVRHED DVQHFKVMRD NKGNYFLWTE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGCATTCCA GCCTGGGCAC GAAGAGTGAA ACTCCATCTC AAAAGAAAAA AAAAAAAGGA 60
GTTATGGGCA GAAAATTACC TCCTTTAACT CATTCGACAA ATGTTTACTG AGCATTTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005768--C:endosome
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

mcc:704410

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001994	Ailuropoda melanoleuca	86.36	1.00e-164	572.00
IUUC-Apl-003684	Anas platyrhynchos	60.98	5.00e-106	377.00
IUUC-Aca-005371	Anolis carolinensis	53.64	4.00e-93	334.00
IUUC-Ame-011392	Astyanax mexicanus	42.99	6.00e-68	250.00
IUUC-Bta-013508	Bos taurus	82.12	2.00e-155	541.00
IUUC-Cja-019613	Callithrix jacchus	81.87	3.00e-69	253.00
IUUC-Cfa-020290	Canis familiaris	86.67	5.00e-165	573.00
IUUC-Cpo-022534	Cavia porcellus	86.97	5.00e-161	560.00
IUUC-Csa-023438	Chlorocebus sabaeus	99.70	4.00e-169	587.00
IUUC-Cho-024466	Choloepus hoffmanni	61.99	1.00e-81	295.00
IUUC-Dre-027927	Danio rerio	45.85	5.00e-74	270.00
IUUC-Dno-029894	Dasypus novemcinctus	85.76	2.00e-161	561.00
IUUC-Dor-030493	Dipodomys ordii	94.77	1.00e-83	303.00
IUUC-Ete-032335	Echinops telfairi	75.45	6.00e-129	453.00
IUUC-Eca-033750	Equus caballus	88.18	1.00e-163	568.00
IUUC-Eeu-034884	Erinaceus europaeus	70.91	1.00e-116	412.00
IUUC-Fca-036001	Felis catus	86.97	2.00e-164	571.00
IUUC-Fal-036692	Ficedula albicollis	60.73	4.00e-105	374.00
IUUC-Gmo-039524	Gadus morhua	63.27	6.00e-53	201.00
IUUC-Gac-041301	Gasterosteus aculeatus	60.12	1.00e-57	216.00
IUUC-Ggo-045424	Gorilla gorilla	98.48	7.00e-168	582.00
IUUC-Hsa-045808	Homo sapiens	98.79	2.00e-168	585.00
IUUC-Itr-048000	Ictidomys tridecemlineatus	89.39	1.00e-156	545.00
IUUC-Lch-049610	Latimeria chalumnae	69.08	2.00e-55	209.00
IUUC-Loc-052925	Lepisosteus oculatus	46.88	2.00e-76	278.00
IUUC-Laf-054004	Loxodonta africana	88.48	1.00e-166	578.00
IUUC-Meu-056169	Macropus eugenii	73.00	2.00e-125	442.00
IUUC-Mga-059483	Meleagris gallopavo	61.68	4.00e-109	387.00
IUUC-Mmr-061755	Microcebus murinus	91.21	5.00e-170	589.00
IUUC-Mdo-062504	Monodelphis domestica	72.89	2.00e-132	465.00
IUUC-Mmu-063557	Mus musculus	83.94	7.00e-156	542.00
IUUC-Mpu-066852	Mustela putorius furo	85.76	1.00e-164	572.00
IUUC-Mlu-067510	Myotis lucifugus	85.54	1.00e-162	565.00
IUUC-Nle-069691	Nomascus leucogenys	98.79	3.00e-168	584.00
IUUC-Opr-070271	Ochotona princeps	82.73	4.00e-150	523.00
IUUC-Ont-072651	Oreochromis niloticus	45.12	2.00e-69	255.00
IUUC-Oan-073183	Ornithorhynchus anatinus	72.51	2.00e-124	438.00
IUUC-Ocu-074899	Oryctolagus cuniculus	76.20	1.00e-134	472.00
IUUC-Ola-086462	Oryzias latipes	46.41	6.00e-72	264.00
IUUC-Oga-088553	Otolemur garnettii	90.39	2.00e-165	574.00
IUUC-Oar-089572	Ovis aries	82.83	8.00e-158	549.00
IUUC-Ptr-090582	Pan troglodytes	99.09	7.00e-169	586.00
IUUC-Pan-092063	Papio anubis	100.00	1.00e-169	588.00
IUUC-Psi-094056	Pelodiscus sinensis	64.65	3.00e-112	398.00
IUUC-Pfo-096115	Poecilia formosa	60.37	6.00e-57	214.00
IUUC-Pab-098217	Pongo abelii	98.79	3.00e-168	584.00
IUUC-Pca-100838	Procavia capensis	87.27	8.00e-157	546.00
IUUC-Pva-102559	Pteropus vampyrus	84.31	7.00e-130	456.00
IUUC-Rno-105926	Rattus norvegicus	72.75	1.00e-130	459.00
IUUC-Sha-106948	Sarcophilus harrisii	70.48	8.00e-125	439.00
IUUC-Ssc-115605	Sus scrofa	85.15	9.00e-155	539.00
IUUC-Tgu-117211	Taeniopygia guttata	59.57	5.00e-106	377.00
IUUC-Tru-118347	Takifugu rubripes	53.03	5.00e-57	213.00
IUUC-Tsy-119441	Tarsius syrichta	86.06	9.00e-163	565.00
IUUC-Tni-119732	Tetraodon nigroviridis	65.99	7.00e-56	210.00
IUUC-Tbe-127289	Tupaia belangeri	80.92	6.00e-137	479.00
IUUC-Ttr-128961	Tursiops truncatus	76.67	8.00e-145	506.00
IUUC-Vpa-130320	Vicugna pacos	78.19	7.00e-81	293.00
IUUC-Xtr-131814	Xenopus tropicalis	49.70	5.00e-80	291.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence