iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011279

Ensembl Protein ID

ENSAMXP00000010802.1

UniProt Accession

W5KT90; W5KT90_ASTMX

Genbank Protein ID

ENSAMXP00000010802

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01042425

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000010110.1	ENSAMXT00000010802.1	ENSAMXP00000010802.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.40e-18	64.3	786	837

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           ++ yd+ + ++ eL+l++Gd+v++   ++  +gW++g  e +g+ G fP+ +ve+
   Q: 786  IARYDFCSRDTRELSLQEGDMVKIY-TKSGANGWWRG--EVNGRVGWFPSTYVEE 837
           678*********************9.99*********..9*************86 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MEPWRQCALW LISCRVLPPH HRVTWPSARV FDLAQTLRDG VLLCQLLNNL RAHTVNLKEI 60
NLRPQMSQFL CLKNIRTFLC ACSEVFGMKK SELFEAFDLF DVRDFGKKYL CTLLIISRNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACAGCGGC TCGGATTAAA CGGCAACAGA GCGCGCGAGC GGTCCAGATT CTCCGTCTGC 60
TGCACGCGAG GAAGTACGGT CCCGTGCGCG CGTGCTGTCT GTTTCCGTGC ACCCCCGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0862--Zinc

Interpro

IPR022613--CAMSAP_CH
IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR002219--PE/DAG-bd
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR000980--SH2
IPR011511--SH3_2
IPR001452--SH3_domain
IPR003096--SM22_calponin

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50001--SH2
PS50002--SH3
PS00479--ZF_DAG_PE_1
PS50081--ZF_DAG_PE_2

Pfam

PF00130--C1_1
PF11971--CAMSAP_CH
PF00169--PH
PF00621--RhoGEF
PF00017--SH2
PF00018--SH3_1
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN
PR00888--SM22CALPONIN

SMART

SM00109--C1
SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0046872--F:metal ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001362	Ailuropoda melanoleuca	65.61	0.00e+00	1074.00
IUUC-Apl-003734	Anas platyrhynchos	65.90	0.00e+00	986.00
IUUC-Aca-004477	Anolis carolinensis	63.70	0.00e+00	1066.00
IUUC-Bta-012722	Bos taurus	65.49	0.00e+00	1067.00
IUUC-Cja-018941	Callithrix jacchus	65.60	0.00e+00	1061.00
IUUC-Cfa-020266	Canis familiaris	63.65	0.00e+00	921.00
IUUC-Cpo-021966	Cavia porcellus	63.28	0.00e+00	881.00
IUUC-Csa-023892	Chlorocebus sabaeus	64.03	0.00e+00	952.00
IUUC-Dre-028199	Danio rerio	63.54	0.00e+00	1038.00
IUUC-Dno-029474	Dasypus novemcinctus	65.25	0.00e+00	1071.00
IUUC-Eca-033961	Equus caballus	64.17	0.00e+00	938.00
IUUC-Eeu-034719	Erinaceus europaeus	51.85	2.00e-151	530.00
IUUC-Fca-036572	Felis catus	64.83	0.00e+00	1035.00
IUUC-Fal-036802	Ficedula albicollis	64.95	0.00e+00	1098.00
IUUC-Gmo-039409	Gadus morhua	68.11	0.00e+00	1106.00
IUUC-Gga-040884	Gallus gallus	66.75	0.00e+00	1111.00
IUUC-Gac-041395	Gasterosteus aculeatus	72.33	0.00e+00	1192.00
IUUC-Ggo-044460	Gorilla gorilla	61.52	0.00e+00	880.00
IUUC-Hsa-046099	Homo sapiens	63.63	0.00e+00	1061.00
IUUC-Itr-048144	Ictidomys tridecemlineatus	61.49	0.00e+00	890.00
IUUC-Lch-049650	Latimeria chalumnae	60.38	2.00e-71	261.00
IUUC-Loc-052487	Lepisosteus oculatus	68.88	0.00e+00	1145.00
IUUC-Laf-054564	Loxodonta africana	66.08	0.00e+00	1076.00
IUUC-Mcc-054622	Macaca mulatta	64.54	0.00e+00	1061.00
IUUC-Meu-056680	Macropus eugenii	60.97	0.00e+00	991.00
IUUC-Mga-060013	Meleagris gallopavo	65.25	0.00e+00	1070.00
IUUC-Mmr-061251	Microcebus murinus	63.28	0.00e+00	1073.00
IUUC-Mdo-061875	Monodelphis domestica	65.80	0.00e+00	1095.00
IUUC-Mmu-063735	Mus musculus	67.02	0.00e+00	1107.00
IUUC-Mpu-065856	Mustela putorius furo	65.72	0.00e+00	1080.00
IUUC-Mlu-068108	Myotis lucifugus	62.83	0.00e+00	1022.00
IUUC-Nle-069863	Nomascus leucogenys	62.11	0.00e+00	1021.00
IUUC-Opr-070372	Ochotona princeps	61.03	0.00e+00	735.00
IUUC-Ont-072286	Oreochromis niloticus	71.11	0.00e+00	1177.00
IUUC-Ocu-074194	Oryctolagus cuniculus	66.31	0.00e+00	1084.00
IUUC-Ola-086336	Oryzias latipes	71.61	0.00e+00	1172.00
IUUC-Oga-089104	Otolemur garnettii	53.42	0.00e+00	859.00
IUUC-Oar-089272	Ovis aries	65.49	0.00e+00	1105.00
IUUC-Ptr-090652	Pan troglodytes	63.72	0.00e+00	1056.00
IUUC-Pan-092550	Papio anubis	62.28	0.00e+00	901.00
IUUC-Psi-093784	Pelodiscus sinensis	61.73	0.00e+00	916.00
IUUC-Pfo-097308	Poecilia formosa	69.76	0.00e+00	1169.00
IUUC-Pab-098698	Pongo abelii	63.49	0.00e+00	1056.00
IUUC-Pva-102262	Pteropus vampyrus	64.83	0.00e+00	1024.00
IUUC-Rno-105421	Rattus norvegicus	66.78	0.00e+00	1106.00
IUUC-Sha-107325	Sarcophilus harrisii	65.33	0.00e+00	1102.00
IUUC-Sar-113456	Sorex araneus	62.38	0.00e+00	1035.00
IUUC-Ssc-115338	Sus scrofa	51.60	0.00e+00	780.00
IUUC-Tgu-116595	Taeniopygia guttata	65.36	0.00e+00	1051.00
IUUC-Tru-117884	Takifugu rubripes	63.00	0.00e+00	1091.00
IUUC-Tsy-119429	Tarsius syrichta	59.92	0.00e+00	850.00
IUUC-Tni-119951	Tetraodon nigroviridis	67.33	0.00e+00	1082.00
IUUC-Tbe-127995	Tupaia belangeri	64.75	3.00e-128	452.00
IUUC-Ttr-128281	Tursiops truncatus	65.49	0.00e+00	1067.00
IUUC-Vpa-130066	Vicugna pacos	46.58	3.00e-33	137.00
IUUC-Xtr-132427	Xenopus tropicalis	57.11	0.00e+00	988.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence