iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013476

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02057919

Gene Name

TRIM72

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000001503.5	ENSBTAT00000037406.4	ENSBTAP00000037239.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.30e-06	27.7	12	78
E3 activity/RING/RING	3.90e-08	33.8	16	59

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwl...asggk....tcPvtrqplteedlvPnltlrrliq 66
           +e+ Cp+ l+l+  Pv++++G+++ r+++ +     a         cP +++p++++ l  nl l rl++
   Q: 12   QELSCPLCLQLFDAPVTAECGHSFCRACLSRVAgepA---AdgtvLCPSCQAPTRPQALSTNLQLARLVE 78
           7899***************************765553...144479****************99988765 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl+ f+  p++  CgH f++ Cl ++      + ++ +CP C+
   Q: 16   CPLCLQLFDA-PVTAECGHSFCRACLSRV-AGEPAADGTVLCPSCQ 59
           ********99.999***************.5555899999*****7 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

PAMSAAPGLL HQELSCPLCL QLFDAPVTAE CGHSFCRACL SRVAGEPAAD GTVLCPSCQA 60
PTRPQALSTN LQLARLVEGL AQVPQGHCEE HLDPLSIYCE QDRALVCGVC ASLGSHRGHR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGCCATGT CGGCCGCGCC CGGCCTCCTG CACCAGGAGC TGTCCTGCCC GCTGTGCCTG 60
CAGCTGTTCG ACGCGCCCGT GACTGCCGAG TGCGGCCACA GCTTCTGTCG CGCCTGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0042383--C:sarcolemma
GO:0001786--F:phosphatidylserine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007517--P:muscle organ development
GO:0003012--P:muscle system process
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0043569--P:negative regulation of insulin-like growth factor receptor signaling pathway
GO:0010832--P:negative regulation of myotube differentiation
GO:0001778--P:plasma membrane repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002377	Ailuropoda melanoleuca	64.62	4.00e-151	527.00
IUUC-Aca-004755	Anolis carolinensis	54.05	5.00e-144	504.00
IUUC-Cel-018370	Caenorhabditis elegans	37.63	5.00e-08	52.00
IUUC-Cja-018969	Callithrix jacchus	70.79	5.00e-175	607.00
IUUC-Cfa-020155	Canis familiaris	78.36	0.00e+00	739.00
IUUC-Cpo-021646	Cavia porcellus	73.35	0.00e+00	692.00
IUUC-Csa-023855	Chlorocebus sabaeus	83.22	2.00e-133	468.00
IUUC-Dno-029142	Dasypus novemcinctus	78.44	0.00e+00	644.00
IUUC-Ete-032801	Echinops telfairi	86.72	7.00e-65	240.00
IUUC-Eca-034378	Equus caballus	81.24	0.00e+00	719.00
IUUC-Eeu-034526	Erinaceus europaeus	72.03	0.00e+00	647.00
IUUC-Fca-036440	Felis catus	80.66	0.00e+00	740.00
IUUC-Ggo-045086	Gorilla gorilla	75.06	2.00e-157	548.00
IUUC-Hsa-046533	Homo sapiens	78.16	0.00e+00	712.00
IUUC-Itr-048959	Ictidomys tridecemlineatus	76.15	0.00e+00	726.00
IUUC-Laf-054479	Loxodonta africana	76.46	0.00e+00	725.00
IUUC-Mcc-055814	Macaca mulatta	76.75	0.00e+00	690.00
IUUC-Meu-056767	Macropus eugenii	62.16	3.00e-163	568.00
IUUC-Mmr-061616	Microcebus murinus	76.55	0.00e+00	725.00
IUUC-Mdo-062252	Monodelphis domestica	64.77	2.00e-171	595.00
IUUC-Mmu-063094	Mus musculus	77.16	0.00e+00	692.00
IUUC-Mpu-065885	Mustela putorius furo	66.67	1.00e-155	542.00
IUUC-Nle-069476	Nomascus leucogenys	78.40	0.00e+00	711.00
IUUC-Opr-070871	Ochotona princeps	69.28	3.00e-102	365.00
IUUC-Oan-072738	Ornithorhynchus anatinus	62.97	5.00e-173	600.00
IUUC-Ocu-074132	Oryctolagus cuniculus	71.98	2.00e-147	515.00
IUUC-Olu-087666	Ostreococcus lucimarinus	39.19	9.00e-11	61.60
IUUC-Oga-088268	Otolemur garnettii	56.73	8.00e-125	440.00
IUUC-Oar-089555	Ovis aries	60.54	5.00e-133	467.00
IUUC-Ptr-090792	Pan troglodytes	78.16	0.00e+00	712.00
IUUC-Pan-092897	Papio anubis	77.76	0.00e+00	709.00
IUUC-Pab-098716	Pongo abelii	78.16	0.00e+00	711.00
IUUC-Pca-100618	Procavia capensis	70.99	0.00e+00	672.00
IUUC-Pva-102430	Pteropus vampyrus	75.73	0.00e+00	681.00
IUUC-Rno-105665	Rattus norvegicus	76.54	0.00e+00	706.00
IUUC-Sha-106854	Sarcophilus harrisii	60.16	1.00e-156	546.00
IUUC-Sar-113028	Sorex araneus	81.14	4.00e-107	380.00
IUUC-Ssc-116124	Sus scrofa	79.88	0.00e+00	752.00
IUUC-Tbe-127273	Tupaia belangeri	78.51	2.00e-104	372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence