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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Ath-007392
Ensembl Protein ID AT1G48360.2
UniProt Accession Q5XVJ4; Q5XVJ5; Q9SX69; FAN1_ARATH
Genbank Protein ID AAD49761.2; AEE32278.1; AEE32279.1; AEE32280.1; AAU44397.1; AAU44398.1; ABK28782.1
Protein Name Fanconi-associated nuclease 1 homolog
Genbank Nucleotide ID AC007932; CP002684; CP002684; CP002684; AY735527; AY735528; DQ653403
Gene Name At1g48360; F11A17.9
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT1G48360 AT1G48360.4 AT1G48360.4
AT1G48360 AT1G48360.2 AT1G48360.2
AT1G48360 AT1G48360.5 AT1G48360.5
AT1G48360 AT1G48360.3 AT1G48360.3
AT1G48360 AT1G48360.1 AT1G48360.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFAC
Protein Expression/Proteomics
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/ZnF/UBZ 30.26 1.00e-70 266.00 IUUC-Hsa-046520
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
 Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
Protein Sequence
(Fasta)
MLTGRESLLR LIGKRRRFLP NRHLLLSAHT PNSLNLEFND YGNLVSLAGD DCRLSEDPTS 60
SDDPSKFSDD LSLSTRKKRR LTQTTLLQSS FLSVPKQLED GLVICTQQKS ILDSETFEFS 120
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Protein Fasta Sequence


>IUUC-Ath-007392|UBD,UBZ|Arabidopsis thaliana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAAAAATAGA GAAACCTTGA ACAAAAAGAC AAAACAGAAA AAGAATTCTC CGACCAAAAA 60
ATATCAAAAT GGTAAACCAA AAGGGCAAAG AAAGAAACTG TAGCGCCAAT CTAAAGATTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ath-007392|UBD,UBZ|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0460--Magnesium
KW-0464--Manganese
KW-0479--Metal-binding
KW-0540--Nuclease
KW-1185--Reference proteome
Interpro

IPR033315--Fan1-like
IPR014905--HIRAN
IPR014883--VRR_NUC
Pfam

PF08797--HIRAN
PF08774--VRR_NUC
SMART

SM00910--HIRAN
SM00990--VRR_NUC
Gene Ontology

GO:0005634--C:nucleus
GO:0008409--F:5'-3' exonuclease activity
GO:0017108--F:5'-flap endonuclease activity
GO:0070336--F:flap-structured DNA binding
GO:0016818--F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0004528--F:phosphodiesterase I activity
GO:0008270--F:zinc ion binding
GO:0036297--P:interstrand cross-link repair
KEGG ath:AT1G48360
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000306 Aegilops tauschii 57.93 2.00e-147 514.00
IUUC-Aml-001380 Ailuropoda melanoleuca 30.44 2.00e-67 250.00
IUUC-Atr-002873 Amborella trichopoda 55.01 0.00e+00 825.00
IUUC-Apl-003430 Anas platyrhynchos 29.42 2.00e-65 243.00
IUUC-Aca-005376 Anolis carolinensis 29.46 2.00e-54 207.00
IUUC-Aly-005463 Arabidopsis lyrata 90.09 0.00e+00 1570.00
IUUC-Acl-008285 Aspergillus clavatus 25.96 6.00e-55 208.00
IUUC-Afl-008680 Aspergillus flavus 28.10 5.00e-62 232.00
IUUC-Afu-008795 Aspergillus fumigatus 28.37 3.00e-55 209.00
IUUC-Ani-009329 Aspergillus nidulans 25.34 2.00e-48 186.00
IUUC-Ang-009526 Aspergillus niger 26.41 3.00e-49 189.00
IUUC-Aor-009880 Aspergillus oryzae 28.45 7.00e-61 228.00
IUUC-Ate-010269 Aspergillus terreus 30.84 3.00e-57 216.00
IUUC-Ame-011630 Astyanax mexicanus 28.35 2.00e-40 160.00
IUUC-Bgr-012168 Blumeria graminis 28.35 2.00e-36 147.00
IUUC-Bta-013504 Bos taurus 30.31 1.00e-60 227.00
IUUC-Bci-013838 Botrytis cinerea 25.67 9.00e-51 194.00
IUUC-Bdi-014522 Brachypodium distachyon 46.84 0.00e+00 649.00
IUUC-Bol-016153 Brassica oleracea 81.97 0.00e+00 1395.00
IUUC-Bra-017548 Brassica rapa 77.17 0.00e+00 1340.00
IUUC-Cel-018711 Caenorhabditis elegans 25.44 1.00e-35 144.00
IUUC-Cja-018810 Callithrix jacchus 29.87 5.00e-60 225.00
IUUC-Cfa-020147 Canis familiaris 30.20 3.00e-66 246.00
IUUC-Cpo-021787 Cavia porcellus 28.73 9.00e-61 228.00
IUUC-Csa-023730 Chlorocebus sabaeus 29.97 4.00e-67 249.00
IUUC-Cho-024754 Choloepus hoffmanni 45.57 6.00e-14 72.40
IUUC-Cin-025459 Ciona intestinalis 39.31 3.00e-29 120.00
IUUC-Cgl-026724 Colletotrichum gloeosporioides 28.46 3.00e-38 152.00
IUUC-Cne-026815 Cryptococcus neoformans 39.52 3.00e-35 143.00
IUUC-Cme-027208 Cyanidioschyzon merolae 28.36 2.00e-33 137.00
IUUC-Dre-027725 Danio rerio 31.52 2.00e-70 260.00
IUUC-Dno-029713 Dasypus novemcinctus 28.85 8.00e-63 234.00
IUUC-Dse-031534 Dothistroma septosporum 27.52 4.00e-48 186.00
IUUC-Ete-033004 Echinops telfairi 36.99 1.00e-19 91.70
IUUC-Eca-034119 Equus caballus 30.31 5.00e-68 252.00
IUUC-Eeu-034618 Erinaceus europaeus 37.03 1.00e-47 184.00
IUUC-Fca-035411 Felis catus 30.03 4.00e-65 242.00
IUUC-Fal-037505 Ficedula albicollis 28.79 1.00e-63 237.00
IUUC-Fox-038070 Fusarium oxysporum 30.19 3.00e-47 183.00
IUUC-Fso-038376 Fusarium solani 25.97 9.00e-53 201.00
IUUC-Gmo-039093 Gadus morhua 30.89 9.00e-71 261.00
IUUC-Ggr-040081 Gaeumannomyces graminis 26.66 2.00e-53 203.00
IUUC-Gac-041973 Gasterosteus aculeatus 29.34 1.00e-71 264.00
IUUC-Gma-043421 Glycine max 58.03 0.00e+00 867.00
IUUC-Ggo-044431 Gorilla gorilla 29.82 1.00e-67 251.00
IUUC-Hsa-046520 Homo sapiens 29.82 2.00e-67 250.00
IUUC-Hvu-047632 Hordeum vulgare 50.47 0.00e+00 738.00
IUUC-Itr-048263 Ictidomys tridecemlineatus 29.72 6.00e-67 248.00
IUUC-Lch-049799 Latimeria chalumnae 29.43 1.00e-66 247.00
IUUC-Lpe-051149 Leersia perrieri 48.10 0.00e+00 752.00
IUUC-Loc-051964 Lepisosteus oculatus 29.07 2.00e-62 234.00
IUUC-Lma-053161 Leptosphaeria maculans 26.95 5.00e-58 218.00
IUUC-Laf-054446 Loxodonta africana 29.10 4.00e-63 235.00
IUUC-Mcc-055087 Macaca mulatta 29.97 6.00e-67 248.00
IUUC-Meu-055930 Macropus eugenii 27.61 1.00e-26 114.00
IUUC-Mor-056966 Magnaporthe oryzae 30.02 6.00e-49 188.00
IUUC-Mpo-057393 Magnaporthe poae 30.16 2.00e-47 183.00
IUUC-Mtr-058315 Medicago truncatula 52.95 0.00e+00 913.00
IUUC-Mla-058859 Melampsora laricipopulina 33.92 9.00e-33 135.00
IUUC-Mga-059870 Meleagris gallopavo 28.71 8.00e-57 215.00
IUUC-Mvi-060226 Microbotryum violaceum 30.67 3.00e-50 193.00
IUUC-Mmr-060892 Microcebus murinus 30.72 6.00e-69 255.00
IUUC-Mdo-062896 Monodelphis domestica 30.00 4.00e-63 236.00
IUUC-Mmu-064276 Mus musculus 31.88 7.00e-75 275.00
IUUC-Mac-064503 Musa acuminata 50.00 0.00e+00 715.00
IUUC-Mpu-066820 Mustela putorius furo 30.18 7.00e-67 248.00
IUUC-Mlu-068131 Myotis lucifugus 30.88 8.00e-64 238.00
IUUC-Nfi-068480 Neosartorya fischeri 28.39 7.00e-55 208.00
IUUC-Ncr-068646 Neurospora crassa 25.86 4.00e-49 189.00
IUUC-Nle-069545 Nomascus leucogenys 28.29 7.00e-58 218.00
IUUC-Opr-070722 Ochotona princeps 32.96 8.00e-57 214.00
IUUC-Ont-072561 Oreochromis niloticus 30.48 2.00e-71 263.00
IUUC-Oan-072811 Ornithorhynchus anatinus 31.28 4.00e-63 236.00
IUUC-Ocu-073884 Oryctolagus cuniculus 29.62 2.00e-63 236.00
IUUC-Oba-075112 Oryza barthii 47.31 0.00e+00 661.00
IUUC-Obr-076057 Oryza brachyantha 50.39 0.00e+00 780.00
IUUC-Ogl-077002 Oryza glaberrima 52.85 0.00e+00 771.00
IUUC-Ogu-078683 Oryza glumaepatula 48.94 0.00e+00 701.00
IUUC-Oin-079952 Oryza indica 49.59 0.00e+00 675.00
IUUC-Olo-080278 Oryza longistaminata 56.25 2.00e-171 595.00
IUUC-Ome-081094 Oryza meridionalis 47.26 0.00e+00 667.00
IUUC-Oni-083059 Oryza nivara 48.07 0.00e+00 669.00
IUUC-Opu-084144 Oryza punctata 49.94 0.00e+00 769.00
IUUC-Oru-084897 Oryza rufipogon 49.46 0.00e+00 687.00
IUUC-Osa-085924 Oryza sativa 52.45 0.00e+00 760.00
IUUC-Oga-088979 Otolemur garnettii 29.94 2.00e-63 236.00
IUUC-Oar-090362 Ovis aries 30.75 9.00e-69 254.00
IUUC-Ptr-090823 Pan troglodytes 29.82 1.00e-67 250.00
IUUC-Pan-092863 Papio anubis 29.97 6.00e-67 248.00
IUUC-Psi-093006 Pelodiscus sinensis 28.75 2.00e-63 237.00
IUUC-Pma-094523 Petromyzon marinus 32.49 7.00e-52 197.00
IUUC-Pno-094770 Phaeosphaeria nodorum 30.14 8.00e-54 204.00
IUUC-Ppa-095372 Physcomitrella patens 42.22 1.00e-173 603.00
IUUC-Pfo-096875 Poecilia formosa 30.03 3.00e-68 253.00
IUUC-Pab-097665 Pongo abelii 29.66 5.00e-67 248.00
IUUC-Pop-099082 Populus trichocarpa 62.11 0.00e+00 953.00
IUUC-Pca-100138 Procavia capensis 33.33 5.00e-11 62.80
IUUC-Ppe-101167 Prunus persica 49.46 1.00e-174 605.00
IUUC-Pva-103199 Pteropus vampyrus 31.18 1.00e-26 114.00
IUUC-Pgr-103480 Puccinia graminis 29.86 7.00e-53 202.00
IUUC-Ptt-103783 Puccinia triticina 30.75 4.00e-51 196.00
IUUC-Pte-104357 Pyrenophora teres 29.16 7.00e-51 194.00
IUUC-Pyt-104788 Pyrenophora triticirepentis 30.72 1.00e-55 211.00
IUUC-Rno-104958 Rattus norvegicus 31.43 2.00e-73 270.00
IUUC-Sha-106828 Sarcophilus harrisii 30.46 7.00e-71 261.00
IUUC-Sja-107731 Schizosaccharomyces japonicus 46.43 2.00e-42 166.00
IUUC-Spo-108086 Schizosaccharomyces pombe 28.76 8.00e-59 221.00
IUUC-Ssl-108610 Sclerotinia sclerotiorum 27.75 9.00e-53 201.00
IUUC-Smo-108690 Selaginella moellendorffii 40.78 1.00e-172 599.00
IUUC-Sit-110385 Setaria italica 47.55 0.00e+00 651.00
IUUC-Sly-111187 Solanum lycopersicum 55.82 0.00e+00 841.00
IUUC-Stu-112673 Solanum tuberosum 70.00 4.00e-67 246.00
IUUC-Sar-113548 Sorex araneus 25.37 1.00e-14 74.70
IUUC-Sbi-114131 Sorghum bicolor 47.53 0.00e+00 704.00
IUUC-Sre-114921 Sporisorium reilianum 36.67 5.00e-35 142.00
IUUC-Ssc-115484 Sus scrofa 31.46 2.00e-69 256.00
IUUC-Tgu-116749 Taeniopygia guttata 29.01 7.00e-67 248.00
IUUC-Tru-118772 Takifugu rubripes 28.83 9.00e-61 227.00
IUUC-Tsy-119359 Tarsius syrichta 28.67 1.00e-54 207.00
IUUC-Tni-120878 Tetraodon nigroviridis 29.29 2.00e-66 246.00
IUUC-Tca-120912 Theobroma cacao 64.34 0.00e+00 983.00
IUUC-Tre-122171 Trichoderma reesei 27.25 2.00e-59 223.00
IUUC-Tvi-122483 Trichoderma virens 27.53 8.00e-57 214.00
IUUC-Tae-125125 Triticum aestivum 49.80 0.00e+00 727.00
IUUC-Tur-126497 Triticum urartu 50.27 0.00e+00 725.00
IUUC-Tbe-127473 Tupaia belangeri 31.11 8.00e-17 81.30
IUUC-Ttr-128458 Tursiops truncatus 29.28 3.00e-55 209.00
IUUC-Uma-129558 Ustilago maydis 35.55 1.00e-34 141.00
IUUC-Vda-129683 Verticillium dahliae 25.97 1.00e-47 184.00
IUUC-Vpa-130201 Vicugna pacos 30.00 2.00e-06 48.10
IUUC-Vvi-131226 Vitis vinifera 68.52 0.00e+00 690.00
IUUC-Xtr-132517 Xenopus tropicalis 30.84 1.00e-62 234.00
IUUC-Xma-133763 Xiphophorus maculatus 29.01 2.00e-67 250.00
IUUC-Zma-135455 Zea mays 48.60 0.00e+00 746.00
Created Date 25-Jun-2017

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