iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	circBase	CircNet
miRTarBase	microRNA	TRANSFAC	TargetScan
RepTar	miRNAMap	SomamiR	miRcode
RAID2
Protein-protein Interaction
HINT	InWeb_IM
Disease-associated Variation
OMIM
Post-translational Modifications (PTMs)
BioGRID
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	2.60e-12	48.6	36	97

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +D+i++++g+ f+ahk+vLaasS++F++     l+ +   +  +ik   p vf++ll+F+Ytg+++
   Q: 36   CDIIVHIQGQPFRAHKAVLAASSPYFRDHS--ALSTMSGLSISVIK--NPNVFEQLLSFCYTGRMS 97
           8***************************75..55544424555666..***************987 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MSVEMDSSSF IQFDVPEYSS TVLSQLNELR LQGKLCDIIV HIQGQPFRAH KAVLAASSPY 60
FRDHSALSTM SGLSISVIKN PNVFEQLLSF CYTGRMSLQL KDVVSFLTAA SFLQMQCVID 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGGACTGG CCTGGCGCCG GCGGCGGCGG AGGGGGCGCC GCGGGCGGGC GATGTGAGCG 60
CGGCGCTCTG GACAGGTGAG GCACGCTGGC CGGGGGCGGC GAGCAGCGGG CTAGGCGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0003676--F:nucleic acid binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002162	Ailuropoda melanoleuca	98.41	0.00e+00	930.00
IUUC-Apl-003429	Anas platyrhynchos	88.80	0.00e+00	874.00
IUUC-Aca-004321	Anolis carolinensis	82.90	0.00e+00	771.00
IUUC-Ath-007213	Arabidopsis thaliana	32.53	1.00e-05	45.40
IUUC-Ame-010796	Astyanax mexicanus	60.00	1.00e-144	506.00
IUUC-Bta-012697	Bos taurus	96.84	0.00e+00	942.00
IUUC-Cja-018866	Callithrix jacchus	100.00	0.00e+00	981.00
IUUC-Cfa-021264	Canis familiaris	98.81	0.00e+00	968.00
IUUC-Cpo-022168	Cavia porcellus	95.42	0.00e+00	941.00
IUUC-Csa-023962	Chlorocebus sabaeus	100.00	0.00e+00	980.00
IUUC-Dre-028421	Danio rerio	62.78	1.00e-147	516.00
IUUC-Dno-028848	Dasypus novemcinctus	98.02	0.00e+00	963.00
IUUC-Ete-033065	Echinops telfairi	97.22	0.00e+00	922.00
IUUC-Eca-033765	Equus caballus	98.02	0.00e+00	925.00
IUUC-Eeu-034453	Erinaceus europaeus	97.02	0.00e+00	958.00
IUUC-Fca-036376	Felis catus	98.81	0.00e+00	968.00
IUUC-Fal-036646	Ficedula albicollis	88.80	0.00e+00	882.00
IUUC-Gga-040167	Gallus gallus	89.00	0.00e+00	880.00
IUUC-Gac-041727	Gasterosteus aculeatus	67.65	3.00e-168	585.00
IUUC-Ggo-045072	Gorilla gorilla	100.00	0.00e+00	981.00
IUUC-Itr-047871	Ictidomys tridecemlineatus	97.62	0.00e+00	959.00
IUUC-Lch-050407	Latimeria chalumnae	81.44	0.00e+00	739.00
IUUC-Laf-054386	Loxodonta africana	98.21	0.00e+00	965.00
IUUC-Mcc-054719	Macaca mulatta	100.00	0.00e+00	981.00
IUUC-Mga-059992	Meleagris gallopavo	90.15	0.00e+00	852.00
IUUC-Mmr-061411	Microcebus murinus	98.81	0.00e+00	972.00
IUUC-Mdo-063003	Monodelphis domestica	92.46	0.00e+00	919.00
IUUC-Mmu-063384	Mus musculus	92.86	0.00e+00	926.00
IUUC-Mpu-066053	Mustela putorius furo	98.02	0.00e+00	952.00
IUUC-Mlu-068054	Myotis lucifugus	97.01	0.00e+00	947.00
IUUC-Nle-070179	Nomascus leucogenys	100.00	0.00e+00	980.00
IUUC-Opr-070421	Ochotona princeps	92.64	0.00e+00	884.00
IUUC-Ont-072109	Oreochromis niloticus	67.08	7.00e-173	600.00
IUUC-Oan-072992	Ornithorhynchus anatinus	75.44	4.00e-180	624.00
IUUC-Ocu-074444	Oryctolagus cuniculus	94.34	0.00e+00	892.00
IUUC-Ola-087462	Oryzias latipes	68.64	1.00e-174	606.00
IUUC-Oga-089039	Otolemur garnettii	98.20	0.00e+00	959.00
IUUC-Ptr-091470	Pan troglodytes	100.00	0.00e+00	981.00
IUUC-Pan-091916	Papio anubis	100.00	0.00e+00	980.00
IUUC-Psi-093416	Pelodiscus sinensis	88.60	0.00e+00	868.00
IUUC-Pfo-097054	Poecilia formosa	66.18	6.00e-164	570.00
IUUC-Pab-097703	Pongo abelii	100.00	0.00e+00	981.00
IUUC-Pva-102222	Pteropus vampyrus	97.42	0.00e+00	927.00
IUUC-Rno-105414	Rattus norvegicus	92.86	0.00e+00	923.00
IUUC-Sha-107516	Sarcophilus harrisii	92.43	0.00e+00	894.00
IUUC-Sly-111885	Solanum lycopersicum	32.53	6.00e-05	42.70
IUUC-Stu-112863	Solanum tuberosum	32.53	7.00e-05	42.40
IUUC-Ssc-116287	Sus scrofa	95.83	0.00e+00	928.00
IUUC-Tgu-116954	Taeniopygia guttata	92.31	0.00e+00	832.00
IUUC-Tru-118334	Takifugu rubripes	67.41	4.00e-158	551.00
IUUC-Tsy-118861	Tarsius syrichta	98.44	0.00e+00	860.00
IUUC-Tni-120446	Tetraodon nigroviridis	66.67	3.00e-165	575.00
IUUC-Tbe-127991	Tupaia belangeri	97.02	0.00e+00	949.00
IUUC-Ttr-128627	Tursiops truncatus	97.62	0.00e+00	936.00
IUUC-Vpa-130321	Vicugna pacos	93.45	0.00e+00	903.00
IUUC-Xtr-132319	Xenopus tropicalis	78.40	0.00e+00	739.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence