iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-116344

Ensembl Protein ID

ENSSSCP00000009255.2

UniProt Accession

F1S8S0; F1S8S0_PIG

Genbank Protein ID

ENSSSCP00000009255

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

FP102127

Gene Name

WHSC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000008682.2	ENSSSCT00000009499.2	ENSSSCP00000009255.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.30e-15	57.6	829	869

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +gg+    l++Ce C  +fHp+Cl+++    +p+ + w+C++Cr
   Q: 829  WCFVCSKGGS----LLCCESCPAAFHPDCLNIE----MPDGS-WFCNDCR 869
           8*********....*******************....9***8.******8 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

ERIQPQQSPL SGPKAVPRAR MKQAPEILGS PNGKAPSCDV SRECSVFLSK AQLSASLQEG 60
VVQKFNGHDA LPFIPAEKLK DLTSRVFNGE PGAHDARLRF ESQEVKGLGT PPHTTPVKNG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTCCTGTC CTTTTGCCAA TATTAGAGCG GCCTCCTGGA GTTGCCGCTG TGGGTGAAGA 60
ATCCAACGGC AGCAGCTCAG GCTGCTGGAG CGGCGTGGGT TCGGGGCCCG GCCCGCGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50118--HMG_BOX_2
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF00505--HMG_box
PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00184--RING
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0043565--F:sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0003289--P:atrial septum primum morphogenesis
GO:0003290--P:atrial septum secundum morphogenesis
GO:0060348--P:bone development
GO:0010452--P:histone H3-K36 methylation
GO:0034770--P:histone H4-K20 methylation
GO:0003149--P:membranous septum morphogenesis
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048298--P:positive regulation of isotype switching to IgA isotypes
GO:2001032--P:regulation of double-strand break repair via nonhomologous end joining
GO:0070201--P:regulation of establishment of protein localization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002181	Ailuropoda melanoleuca	86.59	0.00e+00	2317.00
IUUC-Apl-003677	Anas platyrhynchos	75.73	0.00e+00	2017.00
IUUC-Aca-004278	Anolis carolinensis	74.07	0.00e+00	1357.00
IUUC-Ame-011932	Astyanax mexicanus	70.22	0.00e+00	1014.00
IUUC-Bta-012522	Bos taurus	87.01	0.00e+00	2261.00
IUUC-Cja-018908	Callithrix jacchus	85.62	0.00e+00	2235.00
IUUC-Cfa-020894	Canis familiaris	85.91	0.00e+00	2358.00
IUUC-Cpo-021982	Cavia porcellus	83.06	0.00e+00	2214.00
IUUC-Csa-023807	Chlorocebus sabaeus	86.15	0.00e+00	2253.00
IUUC-Cho-024405	Choloepus hoffmanni	68.98	0.00e+00	672.00
IUUC-Dre-027492	Danio rerio	70.77	0.00e+00	1054.00
IUUC-Dno-030020	Dasypus novemcinctus	82.57	0.00e+00	1934.00
IUUC-Dor-031103	Dipodomys ordii	78.21	0.00e+00	2013.00
IUUC-Ete-032488	Echinops telfairi	77.58	0.00e+00	1993.00
IUUC-Eca-034066	Equus caballus	85.84	0.00e+00	2328.00
IUUC-Eeu-035199	Erinaceus europaeus	69.07	0.00e+00	727.00
IUUC-Fca-035434	Felis catus	84.77	0.00e+00	1942.00
IUUC-Fal-037113	Ficedula albicollis	73.79	0.00e+00	2008.00
IUUC-Gmo-039686	Gadus morhua	70.73	0.00e+00	1007.00
IUUC-Gga-040273	Gallus gallus	73.95	0.00e+00	1986.00
IUUC-Gac-042123	Gasterosteus aculeatus	49.89	0.00e+00	1201.00
IUUC-Ggo-044643	Gorilla gorilla	85.82	0.00e+00	2280.00
IUUC-Hsa-046380	Homo sapiens	85.75	0.00e+00	2244.00
IUUC-Itr-048658	Ictidomys tridecemlineatus	89.39	0.00e+00	1401.00
IUUC-Lch-050217	Latimeria chalumnae	65.58	0.00e+00	1673.00
IUUC-Lpe-051201	Leersia perrieri	27.54	2.00e-10	60.80
IUUC-Loc-052766	Lepisosteus oculatus	57.96	0.00e+00	1256.00
IUUC-Laf-053780	Loxodonta africana	83.90	0.00e+00	2279.00
IUUC-Mcc-054928	Macaca mulatta	86.23	0.00e+00	2284.00
IUUC-Mga-059576	Meleagris gallopavo	74.78	0.00e+00	1994.00
IUUC-Mmr-061045	Microcebus murinus	84.23	0.00e+00	2284.00
IUUC-Mdo-062576	Monodelphis domestica	77.41	0.00e+00	2082.00
IUUC-Mmu-063640	Mus musculus	83.50	0.00e+00	2217.00
IUUC-Mac-065303	Musa acuminata	28.66	4.00e-10	59.70
IUUC-Mpu-066512	Mustela putorius furo	86.50	0.00e+00	2300.00
IUUC-Mlu-067280	Myotis lucifugus	78.82	0.00e+00	1078.00
IUUC-Nle-069896	Nomascus leucogenys	85.78	0.00e+00	2162.00
IUUC-Ont-072197	Oreochromis niloticus	71.51	0.00e+00	1015.00
IUUC-Oan-072724	Ornithorhynchus anatinus	76.17	0.00e+00	1306.00
IUUC-Ocu-074758	Oryctolagus cuniculus	82.32	0.00e+00	2164.00
IUUC-Ogl-077641	Oryza glaberrima	28.25	2.00e-10	59.70
IUUC-Oin-079557	Oryza indica	28.90	3.00e-10	59.30
IUUC-Olo-080702	Oryza longistaminata	41.47	2.00e-45	177.00
IUUC-Opu-083371	Oryza punctata	41.88	2.00e-47	184.00
IUUC-Osa-085353	Oryza sativa	28.25	2.00e-10	59.70
IUUC-Oga-088702	Otolemur garnettii	83.97	0.00e+00	1945.00
IUUC-Oar-089736	Ovis aries	80.60	0.00e+00	1916.00
IUUC-Ptr-091055	Pan troglodytes	85.97	0.00e+00	2243.00
IUUC-Pan-092752	Papio anubis	91.98	0.00e+00	1388.00
IUUC-Psi-093620	Pelodiscus sinensis	76.69	0.00e+00	2035.00
IUUC-Pfo-097464	Poecilia formosa	50.45	0.00e+00	1192.00
IUUC-Pab-098051	Pongo abelii	85.67	0.00e+00	2271.00
IUUC-Pop-099927	Populus trichocarpa	28.10	8.00e-12	65.50
IUUC-Pca-100273	Procavia capensis	83.59	0.00e+00	2235.00
IUUC-Ppe-101635	Prunus persica	28.80	2.00e-11	64.30
IUUC-Pva-102473	Pteropus vampyrus	79.32	0.00e+00	1915.00
IUUC-Rno-105056	Rattus norvegicus	83.84	0.00e+00	2235.00
IUUC-Sha-107494	Sarcophilus harrisii	78.05	0.00e+00	2071.00
IUUC-Sar-113310	Sorex araneus	85.59	0.00e+00	1776.00
IUUC-Sbi-114581	Sorghum bicolor	31.48	3.00e-09	55.50
IUUC-Tgu-116786	Taeniopygia guttata	75.89	0.00e+00	2004.00
IUUC-Tru-117638	Takifugu rubripes	50.04	0.00e+00	1221.00
IUUC-Tsy-118937	Tarsius syrichta	89.37	0.00e+00	1474.00
IUUC-Tni-120452	Tetraodon nigroviridis	54.46	0.00e+00	1164.00
IUUC-Tae-125237	Triticum aestivum	28.08	2.00e-06	46.20
IUUC-Tbe-127291	Tupaia belangeri	82.16	0.00e+00	1461.00
IUUC-Ttr-129017	Tursiops truncatus	83.38	0.00e+00	1727.00
IUUC-Xtr-132673	Xenopus tropicalis	66.23	0.00e+00	1726.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence