iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-120452

Ensembl Protein ID

ENSTNIP00000015371.1

UniProt Accession

H3D4D3; H3D4D3_TETNG

Protein Name

Histone-lysine N-methyltransferase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000012402.1	ENSTNIT00000015576.1	ENSTNIP00000015371.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.70e-10	41.1	638	680

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC +   +   l++Ce C  +fHp+Cl+++    +p+ + w+C++Cr
   Q: 638  WCFVCSKVPGGR--LLCCESCPAAFHPDCLNIA----MPDGS-WFCNDCR 680
           8******99987..*******************....9***8.******8 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

ITLSVGDLVW TKVSGYPWWP CMVTSDPEIN CHFKQKQKAS SSKTGALYHV QYFGDAPERG 60
YIFEKNMVPF TGEDQYQDLC QCKKKPASRS VHKKMAPSVP RKLRAQWNMG IIQANEALSM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCACGCTCT CTGTTGGGGA TTTAGTGTGG ACAAAGGTGT CGGGATACCC CTGGTGGCCT 60
TGCATGGTGA CCTCTGACCC CGAAATCAAC TGTCACTTCA AACAGAAGCA GAAAGGTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD
PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0051216--P:cartilage development
GO:0048706--P:embryonic skeletal system development
GO:0010452--P:histone H3-K36 methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002181	Ailuropoda melanoleuca	70.29	0.00e+00	1035.00
IUUC-Aca-004278	Anolis carolinensis	71.53	0.00e+00	1050.00
IUUC-Bta-012522	Bos taurus	71.64	0.00e+00	1029.00
IUUC-Bra-017530	Brassica rapa	32.00	1.00e-12	68.90
IUUC-Cja-018908	Callithrix jacchus	71.24	0.00e+00	1025.00
IUUC-Cfa-020894	Canis familiaris	70.14	0.00e+00	1044.00
IUUC-Cpo-021982	Cavia porcellus	71.79	0.00e+00	1041.00
IUUC-Csa-023807	Chlorocebus sabaeus	71.20	0.00e+00	1026.00
IUUC-Csv-026298	Ciona savignyi	39.66	1.00e-54	207.00
IUUC-Dre-027492	Danio rerio	78.90	0.00e+00	1189.00
IUUC-Dor-031103	Dipodomys ordii	65.29	0.00e+00	893.00
IUUC-Dme-032193	Drosophila melanogaster	36.54	4.00e-115	409.00
IUUC-Ete-032488	Echinops telfairi	64.65	0.00e+00	897.00
IUUC-Eca-034066	Equus caballus	53.66	0.00e+00	1162.00
IUUC-Eeu-035199	Erinaceus europaeus	54.57	1.00e-111	398.00
IUUC-Fca-035434	Felis catus	67.00	0.00e+00	974.00
IUUC-Fal-037113	Ficedula albicollis	71.53	0.00e+00	1066.00
IUUC-Gmo-039686	Gadus morhua	76.77	0.00e+00	1124.00
IUUC-Gga-040273	Gallus gallus	71.80	0.00e+00	1061.00
IUUC-Gac-042123	Gasterosteus aculeatus	69.43	0.00e+00	1543.00
IUUC-Ggo-044643	Gorilla gorilla	69.87	0.00e+00	1030.00
IUUC-Hsa-046380	Homo sapiens	71.34	0.00e+00	1026.00
IUUC-Itr-048658	Ictidomys tridecemlineatus	69.58	0.00e+00	1007.00
IUUC-Lch-049684	Latimeria chalumnae	63.60	0.00e+00	905.00
IUUC-Loc-052766	Lepisosteus oculatus	74.01	0.00e+00	1132.00
IUUC-Laf-053780	Loxodonta africana	54.36	0.00e+00	1170.00
IUUC-Mcc-054928	Macaca mulatta	69.73	0.00e+00	1030.00
IUUC-Mga-059576	Meleagris gallopavo	71.94	0.00e+00	1059.00
IUUC-Mmr-061045	Microcebus murinus	70.30	0.00e+00	1043.00
IUUC-Mdo-062576	Monodelphis domestica	70.16	0.00e+00	1043.00
IUUC-Mmu-063640	Mus musculus	71.64	0.00e+00	1036.00
IUUC-Mpu-066512	Mustela putorius furo	70.57	0.00e+00	1040.00
IUUC-Mlu-067261	Myotis lucifugus	64.19	0.00e+00	933.00
IUUC-Nle-069896	Nomascus leucogenys	70.38	0.00e+00	958.00
IUUC-Ont-072197	Oreochromis niloticus	91.43	0.00e+00	1263.00
IUUC-Oan-073496	Ornithorhynchus anatinus	64.49	0.00e+00	919.00
IUUC-Ocu-074758	Oryctolagus cuniculus	70.90	0.00e+00	1028.00
IUUC-Oga-088702	Otolemur garnettii	72.38	0.00e+00	838.00
IUUC-Oar-090265	Ovis aries	63.45	0.00e+00	932.00
IUUC-Ptr-091055	Pan troglodytes	71.34	0.00e+00	1027.00
IUUC-Pan-092752	Papio anubis	71.49	0.00e+00	1011.00
IUUC-Psi-093620	Pelodiscus sinensis	71.95	0.00e+00	1073.00
IUUC-Pma-094747	Petromyzon marinus	57.45	0.00e+00	873.00
IUUC-Ppa-095277	Physcomitrella patens	29.55	2.00e-11	63.90
IUUC-Pfo-097464	Poecilia formosa	70.59	0.00e+00	1509.00
IUUC-Pab-098051	Pongo abelii	69.87	0.00e+00	1030.00
IUUC-Pca-100273	Procavia capensis	70.57	0.00e+00	1024.00
IUUC-Pva-102473	Pteropus vampyrus	67.70	0.00e+00	898.00
IUUC-Rno-105056	Rattus norvegicus	69.76	0.00e+00	1034.00
IUUC-Sha-107494	Sarcophilus harrisii	70.30	0.00e+00	1038.00
IUUC-Sbi-114581	Sorghum bicolor	30.17	1.00e-09	56.60
IUUC-Ssc-116344	Sus scrofa	68.14	0.00e+00	1030.00
IUUC-Tru-117638	Takifugu rubripes	75.39	0.00e+00	1657.00
IUUC-Tsy-118937	Tarsius syrichta	69.51	0.00e+00	1031.00
IUUC-Tbe-127291	Tupaia belangeri	68.63	0.00e+00	976.00
IUUC-Xtr-132673	Xenopus tropicalis	66.99	0.00e+00	1001.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence