iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000009628.1	ENSOART00000010481.1	ENSOARP00000010327.1
ENSOARG00000009628.1	ENSOART00000010482.1	ENSOARP00000010328.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.00e-68	229.5	212	499

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgy 87
           +Gl+NlgNtC++N+vLQcLs++++lr+++l+  ++++++     ++ +el++++++++ +lw  ++ +av+p+++ ++++k+ ++fsgy
   Q: 212  VGLRNLGNTCFLNAVLQCLSSTRPLRDFCLRrDFRQEVPG---GGRAQELTEAFADVIGALWhPDSCEAVNPTRFRAVFQKYVPSFSGY 297
           6******************************667777776...5789***************888899********************* PP
   S: 88   eqqDaqEflaflldqleeelkk..................eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikcle 158
           +qqDaqEfl+ l+++l+ e+++                  +      ee e ++ ++ +  +++  ++++s i+dlF gqlks +kc++
   Q: 298  SQQDAQEFLKLLMERLHLEINRrgrrappilasspappppRLGGALLEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCLKCQA 386
           ********************9988777777777776666655555555555555566666***************************** PP
   S: 159  cdnvssreepfldlslpvpgkeet.kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksr 246
           c+ +s+++e f+dlslp+p+k     k sl+dc++ ftkeeele+en+  c++c++k++++kkl+++++P++L+lhL+Rf  s +++s 
   Q: 387  CGYRSTTFEVFCDLSLPIPKKGFAgGKVSLRDCFNLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRF--SASRGSI 473
           *******************887541456****************************************************..5566899 PP
   S: 247  ekinkkvefple.Ldlspfctspeek 271
           +k +  v+fpl+ L+l  f +++  +
   Q: 474  KKSSVGVDFPLQrLSLGDFASDKAGE 499
           9*********999****999986554 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MPQASEHRLG RTREPPLNIQ PRVGSKLPFA PRARSKERRN PGPGPNPMLR PLPPRPGPPE 60
ERLKKLELGR GRTSGPRPSG PLRADHGVPL PGSPPPTVAL PLPSRTNLAR SKSVSSGDLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GACCTGACCC CAGTTGGCCT CCCCCTCCGC CTCACTCGGG GACAGGTACG GTCCGGGGCG 60
TATGGCGTGG GGGGTTCCGA GGGAAGACTG CTCCAGACTC GAGAGATCGC CCTCCACAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0019784--F:NEDD8-specific protease activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001858	Ailuropoda melanoleuca	92.93	0.00e+00	847.00
IUUC-Aca-004612	Anolis carolinensis	56.56	3.00e-140	492.00
IUUC-Bta-012626	Bos taurus	95.79	0.00e+00	832.00
IUUC-Cja-018853	Callithrix jacchus	93.12	0.00e+00	856.00
IUUC-Cfa-021167	Canis familiaris	97.19	0.00e+00	843.00
IUUC-Cpo-021305	Cavia porcellus	94.59	0.00e+00	785.00
IUUC-Csa-023454	Chlorocebus sabaeus	93.31	0.00e+00	862.00
IUUC-Cho-024836	Choloepus hoffmanni	83.44	9.00e-67	247.00
IUUC-Dre-028454	Danio rerio	53.08	3.00e-85	308.00
IUUC-Dno-029955	Dasypus novemcinctus	90.89	1.00e-178	619.00
IUUC-Dor-031053	Dipodomys ordii	91.59	0.00e+00	873.00
IUUC-Ete-032416	Echinops telfairi	93.50	4.00e-100	358.00
IUUC-Eca-033817	Equus caballus	92.54	0.00e+00	843.00
IUUC-Fca-036400	Felis catus	96.00	0.00e+00	832.00
IUUC-Gmo-038926	Gadus morhua	53.63	1.00e-78	286.00
IUUC-Gac-041331	Gasterosteus aculeatus	52.35	3.00e-83	301.00
IUUC-Ggo-045174	Gorilla gorilla	93.31	0.00e+00	862.00
IUUC-Hsa-046443	Homo sapiens	93.12	0.00e+00	862.00
IUUC-Itr-048329	Ictidomys tridecemlineatus	92.02	0.00e+00	842.00
IUUC-Loc-051808	Lepisosteus oculatus	54.46	1.00e-90	326.00
IUUC-Laf-053730	Loxodonta africana	94.01	0.00e+00	840.00
IUUC-Mcc-055541	Macaca mulatta	93.31	0.00e+00	862.00
IUUC-Meu-056279	Macropus eugenii	89.58	0.00e+00	803.00
IUUC-Mmr-060913	Microcebus murinus	92.54	0.00e+00	798.00
IUUC-Mdo-061807	Monodelphis domestica	89.58	0.00e+00	731.00
IUUC-Mmu-063599	Mus musculus	90.89	0.00e+00	800.00
IUUC-Mpu-066329	Mustela putorius furo	93.69	0.00e+00	845.00
IUUC-Mlu-067359	Myotis lucifugus	89.67	0.00e+00	823.00
IUUC-Nle-068975	Nomascus leucogenys	91.40	0.00e+00	838.00
IUUC-Opr-071096	Ochotona princeps	89.10	0.00e+00	785.00
IUUC-Ocu-074228	Oryctolagus cuniculus	92.21	0.00e+00	835.00
IUUC-Oga-088007	Otolemur garnettii	73.09	1.00e-178	619.00
IUUC-Ptr-091522	Pan troglodytes	93.31	0.00e+00	862.00
IUUC-Pan-091954	Papio anubis	93.12	0.00e+00	861.00
IUUC-Psi-093216	Pelodiscus sinensis	57.14	2.00e-158	552.00
IUUC-Pab-098691	Pongo abelii	93.12	0.00e+00	860.00
IUUC-Pca-101133	Procavia capensis	86.95	0.00e+00	781.00
IUUC-Pva-102681	Pteropus vampyrus	89.48	0.00e+00	795.00
IUUC-Rno-105132	Rattus norvegicus	91.40	0.00e+00	843.00
IUUC-Sha-107145	Sarcophilus harrisii	89.58	0.00e+00	773.00
IUUC-Ssc-115586	Sus scrofa	98.19	0.00e+00	832.00
IUUC-Tgu-117491	Taeniopygia guttata	81.48	2.00e-112	397.00
IUUC-Tni-120746	Tetraodon nigroviridis	52.25	7.00e-81	294.00
IUUC-Tbe-127465	Tupaia belangeri	87.28	3.00e-83	302.00
IUUC-Ttr-128274	Tursiops truncatus	91.40	0.00e+00	797.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence