iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-016722

Ensembl Protein ID

Bra040685.1-P

UniProt Accession

M4FHV6; M4FHV6_BRARP

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra040685	Bra040685.1	Bra040685.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.40e-105	354.4	797	1143

Active Site

Position(s)	Description	Evidence
1111	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           s+lk++++v+fv+     E+gld+gG+++efl+ ++k+ + +++glf ++ ++++ l p+p++ + + + +++ eflGr++gkal++g lld+ 
   Q: 797  SRLKSSIHVSFVNesglpEAGLDYGGLSKEFLTDITKAAFASEYGLFSQTTTSDRLLVPSPSARYLE-NGIQMIEFLGRIVGKALYEGILLDYS 889
           6899*********8888888*****************************************998865.9************************* PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkeg 185
           +s++f+++llg+   +++l+ +dpely++l++ik++ e d++el+ld  f+v+ee +g+++  eLkpgG++i+VtneNk +Y++++++y+l+++
   Q: 890  FSHVFIQKLLGRYSFIDELSGLDPELYRNLMYIKQY-EGDLQELCLD--FTVTEEFCGKMSIIELKPGGKDISVTNENKMQYIHAMADYKLNRQ 980
           ************9999********************.6688876555..5566999************************************** PP
   S: 186  ikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgG 278
           i    +af++G++++i++ +l+lF+++e+++l++G  ++idv+dl+++tky+ggy+++s++i+ Fwev+++f+  er+++L+FvT++sr+Pl G
   Q: 981  IVPFSNAFYRGLTDLISPAWLKLFNAHEFNQLLSGGnHDIDVDDLRRNTKYTGGYSDSSRTIKIFWEVMKGFEPSERCMLLKFVTSCSRAPLLG 1074
           **********************************998********************************************************* PP
   S: 279  faelkprlfvirk...........dasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           f++l+p  f+i+k            ++d +rlPs++TC+n+LkLP+Y+  ++++ekLlyAi++++gFels
   Q: 1075 FKYLQPT-FIIHKvscdtslwaaiGGQDvERLPSASTCYNTLKLPTYKRASTMREKLLYAITSNTGFELS 1143
           *****88.999999*********955555**************************************985 PP

Organism

Brassica rapa

Protein Sequence
(Fasta)

MDLNRKHKVS LRGASSEEMS RDALLAKVSQ ARELRSYARR ANAAAVFIQR VWRSYIVRKK 60
AAFVIQDEWE SSLSCHSDTL TKSWVSSRVL RPFLFFIRSL CVQHQKIEPR DVQCMQTCFK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACCTTA ATCGGAAACA CAAGGTACCT CCTTCTTCTT CCGATCATCT TCTCTATTTA 60
CAATTCGCTT CCGAATTGGT GCATGATGAT GGATCTGTGT GTTTGTTCTC GTCAGGTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	55.97	0.00e+00	1074.00
IUUC-Aml-002107	Ailuropoda melanoleuca	40.00	2.00e-113	403.00
IUUC-Atr-003017	Amborella trichopoda	53.37	0.00e+00	1234.00
IUUC-Apl-003328	Anas platyrhynchos	40.18	1.00e-114	407.00
IUUC-Aly-005794	Arabidopsis lyrata	87.59	0.00e+00	2043.00
IUUC-Ath-007269	Arabidopsis thaliana	88.89	0.00e+00	2107.00
IUUC-Ago-007748	Ashbya gossypii	38.53	2.00e-76	280.00
IUUC-Acl-008158	Aspergillus clavatus	38.69	3.00e-75	276.00
IUUC-Afl-008398	Aspergillus flavus	39.96	1.00e-77	285.00
IUUC-Afu-008937	Aspergillus fumigatus	38.05	4.00e-76	280.00
IUUC-Ani-009252	Aspergillus nidulans	38.70	3.00e-83	303.00
IUUC-Ang-009773	Aspergillus niger	36.18	1.00e-74	275.00
IUUC-Aor-009940	Aspergillus oryzae	39.96	1.00e-77	285.00
IUUC-Ate-010395	Aspergillus terreus	37.68	5.00e-75	276.00
IUUC-Bgr-012269	Blumeria graminis	39.66	4.00e-76	278.00
IUUC-Bta-013547	Bos taurus	40.00	3.00e-114	406.00
IUUC-Bdi-014502	Brachypodium distachyon	54.68	0.00e+00	1159.00
IUUC-Bol-015093	Brassica oleracea	95.28	0.00e+00	2202.00
IUUC-Cel-018447	Caenorhabditis elegans	37.56	1.00e-98	354.00
IUUC-Cja-019855	Callithrix jacchus	40.00	7.00e-114	405.00
IUUC-Cfa-020066	Canis familiaris	39.12	4.00e-108	385.00
IUUC-Cpo-021504	Cavia porcellus	40.36	5.00e-115	409.00
IUUC-Cre-022673	Chlamydomonas reinhardtii	47.41	4.00e-116	412.00
IUUC-Csa-023579	Chlorocebus sabaeus	40.18	1.00e-114	407.00
IUUC-Cin-025750	Ciona intestinalis	38.42	2.00e-101	363.00
IUUC-Csv-026016	Ciona savignyi	38.57	4.00e-104	372.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	38.34	4.00e-85	309.00
IUUC-Cne-026841	Cryptococcus neoformans	35.38	2.00e-86	313.00
IUUC-Dre-028271	Danio rerio	40.71	3.00e-115	409.00
IUUC-Dno-029054	Dasypus novemcinctus	39.82	1.00e-113	404.00
IUUC-Dor-030938	Dipodomys ordii	38.79	3.00e-107	383.00
IUUC-Dse-031416	Dothistroma septosporum	36.61	2.00e-76	280.00
IUUC-Dme-031602	Drosophila melanogaster	38.80	4.00e-108	385.00
IUUC-Eca-034411	Equus caballus	40.18	1.00e-114	407.00
IUUC-Eeu-035201	Erinaceus europaeus	34.82	8.00e-76	278.00
IUUC-Fca-036594	Felis catus	39.64	6.00e-113	402.00
IUUC-Fal-037317	Ficedula albicollis	40.18	1.00e-114	407.00
IUUC-Fox-037788	Fusarium oxysporum	37.39	4.00e-82	299.00
IUUC-Fso-038088	Fusarium solani	37.55	1.00e-82	301.00
IUUC-Gmo-039412	Gadus morhua	39.96	2.00e-111	397.00
IUUC-Gga-040149	Gallus gallus	40.18	1.00e-114	407.00
IUUC-Gac-042088	Gasterosteus aculeatus	40.18	2.00e-112	400.00
IUUC-Gma-042728	Glycine max	60.29	0.00e+00	1407.00
IUUC-Ggo-045279	Gorilla gorilla	40.00	7.00e-114	404.00
IUUC-Hsa-045660	Homo sapiens	40.00	7.00e-114	405.00
IUUC-Hvu-047102	Hordeum vulgare	55.25	0.00e+00	1065.00
IUUC-Lch-050664	Latimeria chalumnae	40.00	8.00e-113	401.00
IUUC-Lpe-050755	Leersia perrieri	49.91	0.00e+00	1018.00
IUUC-Loc-052791	Lepisosteus oculatus	40.46	4.00e-112	399.00
IUUC-Lma-053096	Leptosphaeria maculans	39.15	2.00e-82	301.00
IUUC-Laf-053902	Loxodonta africana	39.89	6.00e-114	405.00
IUUC-Mcc-054730	Macaca mulatta	40.18	1.00e-114	407.00
IUUC-Meu-056527	Macropus eugenii	35.60	2.00e-92	333.00
IUUC-Mor-057021	Magnaporthe oryzae	37.66	3.00e-75	276.00
IUUC-Mpo-057570	Magnaporthe poae	39.09	8.00e-80	292.00
IUUC-Mtr-057671	Medicago truncatula	58.95	0.00e+00	1373.00
IUUC-Mga-059260	Meleagris gallopavo	40.18	1.00e-114	407.00
IUUC-Mvi-060445	Microbotryum violaceum	35.59	7.00e-93	335.00
IUUC-Mmr-060804	Microcebus murinus	40.00	6.00e-114	405.00
IUUC-Mdo-062575	Monodelphis domestica	40.18	2.00e-112	399.00
IUUC-Mmu-063636	Mus musculus	40.04	3.00e-113	403.00
IUUC-Mac-064989	Musa acuminata	53.59	0.00e+00	1140.00
IUUC-Mlu-067952	Myotis lucifugus	40.00	6.00e-114	405.00
IUUC-Nfi-068280	Neosartorya fischeri	38.05	4.00e-76	279.00
IUUC-Ncr-068869	Neurospora crassa	36.25	3.00e-87	317.00
IUUC-Nle-069153	Nomascus leucogenys	40.00	6.00e-114	405.00
IUUC-Opr-070554	Ochotona princeps	39.64	2.00e-112	400.00
IUUC-Ont-071372	Oreochromis niloticus	40.54	8.00e-114	404.00
IUUC-Ocu-074183	Oryctolagus cuniculus	40.00	3.00e-114	406.00
IUUC-Oba-075213	Oryza barthii	54.45	0.00e+00	1005.00
IUUC-Obr-076320	Oryza brachyantha	54.13	0.00e+00	1108.00
IUUC-Ogl-077093	Oryza glaberrima	53.22	0.00e+00	1142.00
IUUC-Ogu-078235	Oryza glumaepatula	50.74	0.00e+00	1036.00
IUUC-Oin-080058	Oryza indica	52.49	0.00e+00	1109.00
IUUC-Olo-080742	Oryza longistaminata	53.77	0.00e+00	1165.00
IUUC-Ome-081741	Oryza meridionalis	52.25	0.00e+00	1092.00
IUUC-Oni-082616	Oryza nivara	51.00	0.00e+00	1049.00
IUUC-Opu-083529	Oryza punctata	54.59	0.00e+00	1033.00
IUUC-Oru-085128	Oryza rufipogon	53.20	0.00e+00	962.00
IUUC-Osa-085557	Oryza sativa	60.81	0.00e+00	892.00
IUUC-Ola-087337	Oryzias latipes	40.71	2.00e-113	403.00
IUUC-Olu-087902	Ostreococcus lucimarinus	46.38	7.00e-101	360.00
IUUC-Oga-088342	Otolemur garnettii	39.93	1.00e-112	400.00
IUUC-Oar-090234	Ovis aries	39.12	2.00e-108	387.00
IUUC-Ptr-091661	Pan troglodytes	39.82	1.00e-113	404.00
IUUC-Pan-092728	Papio anubis	39.93	7.00e-113	401.00
IUUC-Psi-093251	Pelodiscus sinensis	39.31	3.00e-99	356.00
IUUC-Pma-094195	Petromyzon marinus	40.14	3.00e-112	399.00
IUUC-Ppa-095544	Physcomitrella patens	64.92	0.00e+00	729.00
IUUC-Pfo-097472	Poecilia formosa	40.54	8.00e-114	404.00
IUUC-Pab-098570	Pongo abelii	40.00	1.00e-113	404.00
IUUC-Pop-099058	Populus trichocarpa	55.86	0.00e+00	912.00
IUUC-Pca-100110	Procavia capensis	37.50	2.00e-101	363.00
IUUC-Ppe-101281	Prunus persica	60.80	0.00e+00	1439.00
IUUC-Pva-102887	Pteropus vampyrus	37.86	8.00e-105	374.00
IUUC-Rno-106028	Rattus norvegicus	37.77	3.00e-95	343.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.28	5.00e-73	269.00
IUUC-Sha-107331	Sarcophilus harrisii	40.00	1.00e-111	397.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	38.82	3.00e-81	296.00
IUUC-Smo-109537	Selaginella moellendorffii	43.34	0.00e+00	850.00
IUUC-Sit-109811	Setaria italica	53.63	0.00e+00	1140.00
IUUC-Sly-111013	Solanum lycopersicum	57.23	0.00e+00	1293.00
IUUC-Sbi-114433	Sorghum bicolor	54.35	0.00e+00	1172.00
IUUC-Sre-115038	Sporisorium reilianum	43.53	7.00e-95	342.00
IUUC-Ssc-116103	Sus scrofa	40.00	1.00e-113	404.00
IUUC-Tgu-117275	Taeniopygia guttata	40.18	2.00e-114	406.00
IUUC-Tru-118681	Takifugu rubripes	40.18	3.00e-113	403.00
IUUC-Tni-120732	Tetraodon nigroviridis	42.51	6.00e-104	372.00
IUUC-Tca-121770	Theobroma cacao	62.36	0.00e+00	1404.00
IUUC-Tre-121892	Trichoderma reesei	41.93	2.00e-92	334.00
IUUC-Tvi-122354	Trichoderma virens	40.71	4.00e-88	319.00
IUUC-Tae-124300	Triticum aestivum	80.43	1.00e-138	484.00
IUUC-Tur-126086	Triticum urartu	54.30	0.00e+00	1053.00
IUUC-Tbe-127461	Tupaia belangeri	36.14	3.00e-89	323.00
IUUC-Ttr-129269	Tursiops truncatus	40.00	1.00e-113	404.00
IUUC-Uma-129343	Ustilago maydis	42.59	3.00e-94	340.00
IUUC-Vda-129748	Verticillium dahliae	36.30	4.00e-73	269.00
IUUC-Vvi-131524	Vitis vinifera	62.08	0.00e+00	1414.00
IUUC-Xtr-132146	Xenopus tropicalis	40.36	4.00e-114	405.00
IUUC-Xma-133526	Xiphophorus maculatus	40.54	7.00e-114	405.00
IUUC-Yli-134496	Yarrowia lipolytica	38.43	3.00e-83	302.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence