iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RAID2
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.80e-19	71.0	63	138
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.30e-10	40.4	170	201

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvv.......g.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv+++v       g g+ f++ + vLaa++++F+++f++++ es+ +  v+i+dv++e+f++l++++Ytg+++++e
   Q: 63   CDVTIEVvtpgsgpGtGRLFSCNRNVLAAACPYFKSMFTGGMYESQ-QASVTIHDVDAESFEVLVDYCYTGRVSLSE 138
           8999999999998867*****************************9.**************************9876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           l Nc++il fAd++d ++L+++a++fi ++Fk
   Q: 170  LTNCTAILKFADAFDHHKLRSQAQSFIAHNFK 201
           58*****************************7 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MQSREDAPRS RRLASPRGGR RPKRISKPSV SAFFTGPEEL KDAAHSAALL AQLKSFYDAR 60
LLCDVTIEVV TPGSGPGTGR LFSCNRNVLA AACPYFKSMF TGGMYESQQA SVTIHDVDAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTTTGCGG TGTCGTCCGC GCTGGTGTGA AGATGCTGGC CGTCGGCTAC GCGATAAAGG 60
GAGGCGGCTC CGCCCCGAAG GCCCAACTGA GTAATTGCGG CCGCGAGCGG AGTCTGTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB

SMART

SM00875--BACK
SM00225--BTB

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

mmu:432879

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Pyt-104491	Pyrenophora triticirepentis	32.08	7.00e-06	44.30
IUUC-Rno-106015	Rattus norvegicus	87.91	0.00e+00	801.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence