iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074145

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02052815

Gene Name

AMFR

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000017212.3	ENSOCUT00000022438.2	ENSOCUP00000023038.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.70e-09	36.4	341	379
UBD/Alpha-Helix/CUE	2.20e-11	43.5	456	497

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC+++++   + lpCgH+fh +Cl  w        +  +CP+Cr
   Q: 341  CAICWDSMQA-ARKLPCGHLFHNSCLRSW------LEQDTSCPTCR 379
           ********99.******************......9*********8 PP

UBD/Alpha-Helix/CUE

   S: 1    dletaleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           +l+ +++q++e+FP+++y ++ ++L ++t s+e +++n+Leg 
   Q: 456  QLNAMAHQIQEMFPQVPYHLVLQDL-QLTRSVEITTDNILEGR 497
           5889*********************.***************95 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MPLLFLERFP WPSLRTYTGL SGLALLGTIV SAYRALSQPE AGPGEQEPLT ASLQPKAPAP 60
AGPGPEGPRA RDVAQYLLSD SLFVWVLVNT ACCVLMLVAK LIQCIVFGPL RVSERQHLKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCGGCCCG CCCCGAGCCC GCCGAGGCTC TTCCGCGCCG GCAGGCGGTA GCAGCGGGAG 60
CGGCGCTGGG CGGAGCGGCG CCAGCAGCCA GGAGCGGCCC GGCCCGGCCC GGCGGTGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE
PS50089--ZF_RING_2

Pfam

PF02845--CUE
PF13639--zf-RING_2

SMART

SM00546--CUE
SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0005794--C:Golgi apparatus
GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0004872--F:receptor activity
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0032092--P:positive regulation of protein binding
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0051259--P:protein oligomerization
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

ocu:100342533

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001300	Ailuropoda melanoleuca	91.38	0.00e+00	1001.00
IUUC-Apl-003404	Anas platyrhynchos	88.61	0.00e+00	951.00
IUUC-Aca-004559	Anolis carolinensis	85.28	0.00e+00	877.00
IUUC-Ame-011640	Astyanax mexicanus	72.79	0.00e+00	839.00
IUUC-Bta-012980	Bos taurus	86.07	0.00e+00	1064.00
IUUC-Cel-018598	Caenorhabditis elegans	25.06	9.00e-35	141.00
IUUC-Cja-019577	Callithrix jacchus	93.00	0.00e+00	1189.00
IUUC-Cfa-020793	Canis familiaris	92.32	0.00e+00	1009.00
IUUC-Cpo-022387	Cavia porcellus	93.00	0.00e+00	1156.00
IUUC-Csa-023168	Chlorocebus sabaeus	93.47	0.00e+00	1197.00
IUUC-Cho-024433	Choloepus hoffmanni	95.04	0.00e+00	848.00
IUUC-Cin-025215	Ciona intestinalis	45.25	5.00e-148	517.00
IUUC-Csv-026133	Ciona savignyi	47.89	3.00e-131	462.00
IUUC-Dre-027594	Danio rerio	69.95	0.00e+00	791.00
IUUC-Dno-029407	Dasypus novemcinctus	94.44	0.00e+00	1015.00
IUUC-Dor-030961	Dipodomys ordii	94.27	0.00e+00	1038.00
IUUC-Ete-032962	Echinops telfairi	85.48	0.00e+00	858.00
IUUC-Eca-033683	Equus caballus	87.42	0.00e+00	1064.00
IUUC-Eeu-034515	Erinaceus europaeus	98.52	4.00e-79	288.00
IUUC-Fca-035398	Felis catus	95.12	0.00e+00	990.00
IUUC-Fal-036758	Ficedula albicollis	81.85	0.00e+00	890.00
IUUC-Gmo-039014	Gadus morhua	68.74	0.00e+00	775.00
IUUC-Gga-040575	Gallus gallus	83.20	0.00e+00	1031.00
IUUC-Gac-041414	Gasterosteus aculeatus	67.97	0.00e+00	756.00
IUUC-Hsa-046272	Homo sapiens	93.47	0.00e+00	1171.00
IUUC-Itr-047956	Ictidomys tridecemlineatus	93.42	0.00e+00	1013.00
IUUC-Lch-050491	Latimeria chalumnae	75.37	0.00e+00	862.00
IUUC-Loc-052758	Lepisosteus oculatus	76.43	0.00e+00	857.00
IUUC-Laf-053452	Loxodonta africana	94.29	0.00e+00	1019.00
IUUC-Mcc-055820	Macaca mulatta	94.16	0.00e+00	1028.00
IUUC-Meu-056726	Macropus eugenii	86.33	0.00e+00	866.00
IUUC-Mga-059937	Meleagris gallopavo	87.46	0.00e+00	953.00
IUUC-Mmr-060730	Microcebus murinus	91.60	0.00e+00	1123.00
IUUC-Mdo-062771	Monodelphis domestica	87.96	0.00e+00	1089.00
IUUC-Mmu-064219	Mus musculus	92.94	0.00e+00	1170.00
IUUC-Mpu-066796	Mustela putorius furo	93.25	0.00e+00	1015.00
IUUC-Mlu-068189	Myotis lucifugus	92.83	0.00e+00	1014.00
IUUC-Nle-069239	Nomascus leucogenys	92.89	0.00e+00	1143.00
IUUC-Opr-070702	Ochotona princeps	89.86	3.00e-145	508.00
IUUC-Ont-072033	Oreochromis niloticus	69.52	0.00e+00	821.00
IUUC-Oan-073717	Ornithorhynchus anatinus	92.98	0.00e+00	867.00
IUUC-Ogl-077929	Oryza glaberrima	53.49	6.00e-11	60.50
IUUC-Ola-087152	Oryzias latipes	67.43	0.00e+00	791.00
IUUC-Oga-088486	Otolemur garnettii	94.32	0.00e+00	1019.00
IUUC-Oar-089310	Ovis aries	93.21	0.00e+00	1035.00
IUUC-Ptr-090649	Pan troglodytes	94.27	0.00e+00	1048.00
IUUC-Pan-091692	Papio anubis	89.42	0.00e+00	1106.00
IUUC-Psi-093064	Pelodiscus sinensis	95.23	0.00e+00	780.00
IUUC-Pma-094763	Petromyzon marinus	77.87	1.00e-97	348.00
IUUC-Ppa-095969	Physcomitrella patens	29.79	6.00e-36	145.00
IUUC-Pfo-096810	Poecilia formosa	70.35	0.00e+00	805.00
IUUC-Pab-097859	Pongo abelii	94.71	0.00e+00	1033.00
IUUC-Pop-099576	Populus trichocarpa	27.06	5.00e-28	119.00
IUUC-Pca-100344	Procavia capensis	90.54	0.00e+00	1079.00
IUUC-Pva-103114	Pteropus vampyrus	67.08	0.00e+00	730.00
IUUC-Rno-105880	Rattus norvegicus	91.30	0.00e+00	1123.00
IUUC-Sha-107015	Sarcophilus harrisii	93.74	0.00e+00	1010.00
IUUC-Smo-109664	Selaginella moellendorffii	31.12	3.00e-33	136.00
IUUC-Sar-113397	Sorex araneus	98.11	0.00e+00	764.00
IUUC-Ssc-115988	Sus scrofa	87.15	2.00e-139	488.00
IUUC-Tgu-116717	Taeniopygia guttata	90.13	0.00e+00	954.00
IUUC-Tru-117805	Takifugu rubripes	68.53	0.00e+00	831.00
IUUC-Tsy-119442	Tarsius syrichta	87.99	0.00e+00	940.00
IUUC-Tni-119777	Tetraodon nigroviridis	70.34	2.00e-173	602.00
IUUC-Tbe-127322	Tupaia belangeri	68.67	3.00e-115	408.00
IUUC-Ttr-128181	Tursiops truncatus	92.65	0.00e+00	1032.00
IUUC-Vpa-130483	Vicugna pacos	86.43	0.00e+00	669.00
IUUC-Xtr-132614	Xenopus tropicalis	77.23	0.00e+00	804.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence