iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042141

UUCD1 version

UUC-GaA-00548

Ensembl Protein ID

ENSGACP00000014630.1

UniProt Accession

G3PAK6; G3PAK6_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000011058.1	ENSGACT00000014656.1	ENSGACP00000014630.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.70e-94	317.4	354	689

Active Site

Position(s)	Description	Evidence
658	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpl 92
           dlkk+l+v+fvgE+gld+gG+t+e++ ll+++++++d+g+f+y  +++++++ + +      ++ + F+++G+l+g+a++++  ld+++
   Q: 354  DLKKKLRVTFVGEAGLDMGGLTKEWFLLLVRQIFHTDYGMFTYMRDSRCHWFSSWKC-----DNYSEFQLVGTLMGLAVYNSIALDIHF 437
           89************************************************9976655.....789************************ PP
   S: 93   sksfyklllgk..............klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtn 167
           +  +y++ll+                 +l+dl++++pel++ l e++++ e ++ee  + l+f+v +e++g +k+++LkpgG++ipVt+
   Q: 438  PLYCYRKLLTPptvpcdqnapvgmaTATLDDLQQIMPELAHGLGELLSY-EGNVEED-FYLMFQVFQEEMGVVKSHNLKPGGDKIPVTK 524
           ********9995555555555555559*********************9.6788885.******************************* PP
   S: 168  eNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleef 256
            N++eYv+l++++ l+++i +q++af+ Gf++v+  + l l+++ee+e+l+cG +e+d+++l+k ++y+ gy +++ +++ Fw+v+ +f
   Q: 525  HNRKEYVQLYIDFLLNKSICKQFAAFYHGFHSVCASDALMLLRPEEVEMLVCGIPELDMSALQKAAQYE-GYGKTETTVRCFWDVVLAF 612
           ********************************************************************5.5****************** PP
   S: 257  sseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
             e +k++L+F+Tgs+r+P+gG+a+l+   f i+k d  +d+lP s+TCfn+++LP+Y  ke lk+kL++Ai++++gF+l+
   Q: 613  PLELQKKLLHFATGSDRVPVGGMADLN---FKISKiDVPTDWLPISHTCFNQICLPPYRRKE-LKQKLTIAISNAEGFGLE 689
           ***************************...8999988899******************9876.9**************985 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

RELPPICSDV RQKHRLSIDT LPPEVKAPFP SDPILPPRTK TTKEFQEDME RAVQSGDWRE 60
VREFYLTTFD SFIEINAAFK DTQREANGSF NTIDDSGVNA KFVNAVYDAL LSTPQDIQKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGGAGCTCC CTCCCATCTG CAGCGACGTG CGACAAAAGC ATCGGCTCTC CATTGACACT 60
CTTCCCCCGG AGGTCAAAGC TCCGTTCCCC TCGGACCCCA TCCTCCCCCC GCGCACCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	76.48	0.00e+00	1129.00
IUUC-Apl-003589	Anas platyrhynchos	77.25	0.00e+00	1104.00
IUUC-Aca-004350	Anolis carolinensis	73.62	0.00e+00	1067.00
IUUC-Ago-007908	Ashbya gossypii	35.80	1.00e-82	301.00
IUUC-Acl-008288	Aspergillus clavatus	33.88	1.00e-88	321.00
IUUC-Afl-008402	Aspergillus flavus	33.28	1.00e-83	303.00
IUUC-Afu-008762	Aspergillus fumigatus	32.84	2.00e-86	314.00
IUUC-Ani-009176	Aspergillus nidulans	33.83	2.00e-85	311.00
IUUC-Ang-009791	Aspergillus niger	34.36	4.00e-87	316.00
IUUC-Aor-009921	Aspergillus oryzae	33.11	1.00e-82	301.00
IUUC-Ate-010295	Aspergillus terreus	34.99	8.00e-93	335.00
IUUC-Ame-010660	Astyanax mexicanus	83.61	8.00e-154	536.00
IUUC-Bgr-011981	Blumeria graminis	39.12	2.00e-85	311.00
IUUC-Bta-012945	Bos taurus	75.65	0.00e+00	1090.00
IUUC-Bci-013697	Botrytis cinerea	37.09	1.00e-75	278.00
IUUC-Cja-019263	Callithrix jacchus	74.89	0.00e+00	1083.00
IUUC-Cfa-020486	Canis familiaris	77.47	0.00e+00	1072.00
IUUC-Cpo-021755	Cavia porcellus	76.97	0.00e+00	1122.00
IUUC-Csa-023814	Chlorocebus sabaeus	75.42	0.00e+00	1026.00
IUUC-Cho-024980	Choloepus hoffmanni	61.88	0.00e+00	848.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	40.00	6.00e-91	329.00
IUUC-Dre-028551	Danio rerio	81.88	0.00e+00	1157.00
IUUC-Dno-029497	Dasypus novemcinctus	73.59	0.00e+00	1032.00
IUUC-Dor-030867	Dipodomys ordii	65.36	0.00e+00	905.00
IUUC-Dse-031239	Dothistroma septosporum	35.17	5.00e-83	303.00
IUUC-Ete-032902	Echinops telfairi	73.31	0.00e+00	905.00
IUUC-Eca-033678	Equus caballus	76.23	0.00e+00	1107.00
IUUC-Eeu-035262	Erinaceus europaeus	63.48	0.00e+00	879.00
IUUC-Fca-035590	Felis catus	76.23	0.00e+00	1122.00
IUUC-Fal-037123	Ficedula albicollis	73.96	0.00e+00	1043.00
IUUC-Fox-037941	Fusarium oxysporum	38.88	1.00e-96	348.00
IUUC-Fso-038388	Fusarium solani	39.88	1.00e-98	355.00
IUUC-Gmo-039553	Gadus morhua	74.22	0.00e+00	943.00
IUUC-Ggr-040110	Gaeumannomyces graminis	39.01	6.00e-91	329.00
IUUC-Gga-040406	Gallus gallus	77.68	0.00e+00	1132.00
IUUC-Ggo-045504	Gorilla gorilla	75.04	0.00e+00	1087.00
IUUC-Hsa-045786	Homo sapiens	75.22	0.00e+00	1084.00
IUUC-Itr-048050	Ictidomys tridecemlineatus	70.95	0.00e+00	1008.00
IUUC-Kpa-049152	Komagataella pastoris	31.27	2.00e-72	267.00
IUUC-Lch-049824	Latimeria chalumnae	77.57	0.00e+00	986.00
IUUC-Loc-052173	Lepisosteus oculatus	79.71	0.00e+00	1134.00
IUUC-Laf-054017	Loxodonta africana	76.23	0.00e+00	1104.00
IUUC-Mcc-055713	Macaca mulatta	75.18	0.00e+00	1090.00
IUUC-Meu-056212	Macropus eugenii	62.04	4.00e-100	358.00
IUUC-Mor-057045	Magnaporthe oryzae	38.22	1.00e-84	308.00
IUUC-Mla-059187	Melampsora laricipopulina	39.36	9.00e-78	283.00
IUUC-Mga-059884	Meleagris gallopavo	70.66	0.00e+00	997.00
IUUC-Mmr-061344	Microcebus murinus	75.22	0.00e+00	1109.00
IUUC-Mdo-062653	Monodelphis domestica	75.25	0.00e+00	1090.00
IUUC-Mmu-063775	Mus musculus	74.24	0.00e+00	1036.00
IUUC-Mpu-066069	Mustela putorius furo	76.28	0.00e+00	1084.00
IUUC-Mlu-067925	Myotis lucifugus	76.38	0.00e+00	1106.00
IUUC-Nfi-068439	Neosartorya fischeri	32.84	2.00e-85	310.00
IUUC-Ncr-068903	Neurospora crassa	37.88	4.00e-90	326.00
IUUC-Nle-070046	Nomascus leucogenys	75.18	0.00e+00	1106.00
IUUC-Opr-071085	Ochotona princeps	63.42	3.00e-109	389.00
IUUC-Ont-072126	Oreochromis niloticus	94.78	0.00e+00	1353.00
IUUC-Oan-072933	Ornithorhynchus anatinus	76.23	0.00e+00	1035.00
IUUC-Ocu-073800	Oryctolagus cuniculus	75.98	0.00e+00	1064.00
IUUC-Ola-086988	Oryzias latipes	92.47	0.00e+00	1326.00
IUUC-Oga-088117	Otolemur garnettii	77.41	0.00e+00	946.00
IUUC-Oar-089371	Ovis aries	75.51	0.00e+00	1076.00
IUUC-Ptr-090551	Pan troglodytes	75.04	0.00e+00	1086.00
IUUC-Pan-092067	Papio anubis	75.36	0.00e+00	1089.00
IUUC-Psi-092963	Pelodiscus sinensis	75.80	0.00e+00	1070.00
IUUC-Pfo-096562	Poecilia formosa	91.74	0.00e+00	1308.00
IUUC-Pab-098680	Pongo abelii	75.07	0.00e+00	1082.00
IUUC-Pca-100986	Procavia capensis	61.26	0.00e+00	734.00
IUUC-Pva-102219	Pteropus vampyrus	68.71	0.00e+00	848.00
IUUC-Pgr-103315	Puccinia graminis	35.30	4.00e-89	323.00
IUUC-Ptt-103736	Puccinia triticina	38.72	2.00e-87	317.00
IUUC-Rno-105270	Rattus norvegicus	74.78	0.00e+00	1045.00
IUUC-Sce-106306	Saccharomyces cerevisiae	32.45	4.00e-72	266.00
IUUC-Sha-106819	Sarcophilus harrisii	76.27	0.00e+00	1119.00
IUUC-Spo-108271	Schizosaccharomyces pombe	33.09	2.00e-84	306.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	37.50	5.00e-78	286.00
IUUC-Sar-113134	Sorex araneus	68.99	0.00e+00	963.00
IUUC-Ssc-115441	Sus scrofa	75.83	0.00e+00	1091.00
IUUC-Tgu-117166	Taeniopygia guttata	75.80	0.00e+00	1055.00
IUUC-Tsy-118898	Tarsius syrichta	66.23	0.00e+00	867.00
IUUC-Tre-122108	Trichoderma reesei	37.00	1.00e-84	308.00
IUUC-Tvi-122644	Trichoderma virens	36.93	8.00e-89	322.00
IUUC-Tme-127004	Tuber melanosporum	34.20	7.00e-99	356.00
IUUC-Tbe-127292	Tupaia belangeri	62.03	0.00e+00	848.00
IUUC-Ttr-128352	Tursiops truncatus	73.04	0.00e+00	1040.00
IUUC-Vda-129969	Verticillium dahliae	39.56	7.00e-90	325.00
IUUC-Vpa-130218	Vicugna pacos	74.15	0.00e+00	768.00
IUUC-Xtr-132594	Xenopus tropicalis	71.86	0.00e+00	1003.00
IUUC-Xma-134157	Xiphophorus maculatus	91.86	0.00e+00	1234.00
IUUC-Yli-134470	Yarrowia lipolytica	31.29	4.00e-73	270.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence