iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062046

UUCD1 version

UUC-MoD-00925

Ensembl Protein ID

ENSMODP00000013602.2

UniProt Accession

F7FW88; F7FW88_MONDO

Protein Name

Uncharacterized protein

Gene Name

RNF125

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000010864.2	ENSMODT00000013851.2	ENSMODP00000013602.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	2.80e-08	33.9	35	94
E3 activity/RING/RING	9.20e-08	32.7	38	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrl 64
            f C++ le+ ++P  + +G+++ rs+I   l++++ tcP +r+ l +e +     ++++
   Q: 35   SFDCSVCLEVLHQPLRTRCGHVFCRSCISTSLRNSKWTCPYCRAYLPSEGVPATDIMKKM 94
           79**********************************9********988877666666665 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C++Cle + + pl ++CgHvf+++C+         + + +++CP+Cr
   Q: 38   CSVCLEVLHQ-PLRTRCGHVFCRSCIsTS------LRNSKWTCPYCR 77
           ********99.888***********9444......4**********8 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MGSALSSDSG RAAPASRATP SSLPRRSEVE LPITSFDCSV CLEVLHQPLR TRCGHVFCRS 60
CISTSLRNSK WTCPYCRAYL PSEGVPATDI MKKMKAVYQN CTECNTQVCL SEMRAHIRTC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTGTACATT AGTTTTTGGA ATTAGTGGGT TTATTAAGAA CTGTATTATT TGACTAGACC 60
TTAATCTCAG TTGCAGTCTA TTCTCATATC TATCTGAACT TTAAATATTT AACATTTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008598--Di19_Zn_binding_dom
IPR034734--ZF_C2HC_RNF
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51803--ZF_C2HC_RNF
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF05605--zf-Di19

SMART

SM00184--RING

Gene Ontology

GO:0000139--C:Golgi membrane
GO:0005622--C:intracellular
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

mdo:100023988

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001992	Ailuropoda melanoleuca	76.82	2.00e-107	381.00
IUUC-Aca-004839	Anolis carolinensis	63.84	1.00e-65	241.00
IUUC-Bta-012827	Bos taurus	74.25	1.00e-104	372.00
IUUC-Cja-018794	Callithrix jacchus	76.39	6.00e-106	376.00
IUUC-Cfa-021234	Canis familiaris	78.20	7.00e-99	352.00
IUUC-Cpo-022412	Cavia porcellus	72.96	6.00e-96	343.00
IUUC-Csa-023406	Chlorocebus sabaeus	76.82	6.00e-107	379.00
IUUC-Cho-024427	Choloepus hoffmanni	63.84	2.00e-63	234.00
IUUC-Dno-030085	Dasypus novemcinctus	76.82	4.00e-107	380.00
IUUC-Dor-030911	Dipodomys ordii	58.37	3.00e-60	224.00
IUUC-Ete-032469	Echinops telfairi	75.86	5.00e-106	376.00
IUUC-Eca-034352	Equus caballus	78.54	4.00e-109	386.00
IUUC-Eeu-034889	Erinaceus europaeus	69.96	4.00e-92	330.00
IUUC-Fca-036116	Felis catus	75.97	2.00e-99	355.00
IUUC-Hsa-046518	Homo sapiens	76.39	5.00e-106	376.00
IUUC-Itr-048344	Ictidomys tridecemlineatus	79.66	1.00e-83	301.00
IUUC-Laf-053363	Loxodonta africana	79.15	2.00e-110	391.00
IUUC-Meu-056101	Macropus eugenii	91.38	1.00e-112	398.00
IUUC-Mmu-063184	Mus musculus	70.71	3.00e-47	180.00
IUUC-Mpu-065708	Mustela putorius furo	75.54	2.00e-105	374.00
IUUC-Mlu-067561	Myotis lucifugus	74.01	2.00e-78	283.00
IUUC-Nle-069665	Nomascus leucogenys	75.81	3.00e-96	343.00
IUUC-Opr-070301	Ochotona princeps	65.24	3.00e-87	314.00
IUUC-Ocu-074562	Oryctolagus cuniculus	77.78	6.00e-56	208.00
IUUC-Oga-088958	Otolemur garnettii	78.11	4.00e-108	383.00
IUUC-Oar-089541	Ovis aries	75.14	9.00e-81	291.00
IUUC-Ptr-090989	Pan troglodytes	76.82	4.00e-107	380.00
IUUC-Pan-092372	Papio anubis	77.25	2.00e-107	381.00
IUUC-Pab-098718	Pongo abelii	67.81	3.00e-88	317.00
IUUC-Pca-100453	Procavia capensis	78.45	4.00e-108	383.00
IUUC-Pva-102931	Pteropus vampyrus	78.11	8.00e-103	365.00
IUUC-Rno-105771	Rattus norvegicus	76.42	7.00e-86	309.00
IUUC-Sha-107557	Sarcophilus harrisii	89.70	2.00e-124	437.00
IUUC-Sar-113435	Sorex araneus	77.78	1.00e-55	207.00
IUUC-Ssc-116388	Sus scrofa	77.25	1.00e-107	381.00
IUUC-Tsy-119439	Tarsius syrichta	77.40	1.00e-81	294.00
IUUC-Tbe-127417	Tupaia belangeri	55.12	5.00e-55	207.00
IUUC-Ttr-129212	Tursiops truncatus	77.25	6.00e-108	383.00
IUUC-Vpa-130153	Vicugna pacos	76.39	2.00e-105	374.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence