iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066719

Ensembl Protein ID

ENSMPUP00000011091.1

UniProt Accession

M3YID4; M3YID4_MUSPF

Genbank Protein ID

ENSMPUP00000011091

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01041164

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000011183.1	ENSMPUT00000011277.1	ENSMPUP00000011091.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.20e-21	76.7	431	477

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g +++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 431  VCLLCGSGNDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 477
           8********988.6*******************.*******7.******5 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MVNKCWXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XSSPWRRRRT 60
AWVAARRRRR KAEKAPGAAV ASTSRICCRR SRVCTRLGPS AARRRAPGAQ PVLTRLRPAV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTCAATA AATGCTGGNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000552	Aegilops tauschii	32.72	2.00e-102	367.00
IUUC-Aml-001963	Ailuropoda melanoleuca	96.74	0.00e+00	2818.00
IUUC-Apl-003770	Anas platyrhynchos	86.40	0.00e+00	2172.00
IUUC-Aca-004867	Anolis carolinensis	79.97	0.00e+00	2481.00
IUUC-Acl-008162	Aspergillus clavatus	31.61	2.00e-114	408.00
IUUC-Bta-012733	Bos taurus	89.68	0.00e+00	2631.00
IUUC-Bdi-014050	Brachypodium distachyon	29.61	6.00e-122	432.00
IUUC-Bol-015336	Brassica oleracea	36.45	3.00e-14	75.50
IUUC-Cja-019050	Callithrix jacchus	93.11	0.00e+00	2900.00
IUUC-Cfa-021015	Canis familiaris	96.54	0.00e+00	2803.00
IUUC-Cpo-022340	Cavia porcellus	93.61	0.00e+00	2695.00
IUUC-Csa-023441	Chlorocebus sabaeus	95.23	0.00e+00	2837.00
IUUC-Cho-024823	Choloepus hoffmanni	96.27	0.00e+00	1751.00
IUUC-Cgl-026613	Colletotrichum gloeosporioides	29.50	1.00e-107	385.00
IUUC-Cne-026851	Cryptococcus neoformans	28.83	9.00e-112	399.00
IUUC-Dre-027707	Danio rerio	60.75	0.00e+00	1836.00
IUUC-Dno-028978	Dasypus novemcinctus	94.35	0.00e+00	2811.00
IUUC-Dor-030854	Dipodomys ordii	83.42	0.00e+00	1876.00
IUUC-Ete-032760	Echinops telfairi	90.31	0.00e+00	1832.00
IUUC-Eca-034370	Equus caballus	94.54	0.00e+00	2679.00
IUUC-Eeu-035012	Erinaceus europaeus	77.11	0.00e+00	1889.00
IUUC-Fca-035494	Felis catus	96.08	0.00e+00	2774.00
IUUC-Fal-037631	Ficedula albicollis	81.69	0.00e+00	2394.00
IUUC-Gmo-039522	Gadus morhua	58.70	0.00e+00	1730.00
IUUC-Gga-040802	Gallus gallus	82.27	0.00e+00	2432.00
IUUC-Gac-041563	Gasterosteus aculeatus	61.92	0.00e+00	1857.00
IUUC-Gma-042675	Glycine max	32.66	7.00e-102	366.00
IUUC-Ggo-044856	Gorilla gorilla	77.29	0.00e+00	2140.00
IUUC-Hsa-045888	Homo sapiens	93.09	0.00e+00	2847.00
IUUC-Hvu-047583	Hordeum vulgare	43.04	1.00e-15	79.00
IUUC-Itr-048297	Ictidomys tridecemlineatus	94.84	0.00e+00	2807.00
IUUC-Lch-050483	Latimeria chalumnae	66.46	0.00e+00	2040.00
IUUC-Lpe-051537	Leersia perrieri	31.68	2.00e-92	335.00
IUUC-Loc-052550	Lepisosteus oculatus	70.55	0.00e+00	2122.00
IUUC-Laf-053761	Loxodonta africana	92.48	0.00e+00	2679.00
IUUC-Mcc-055505	Macaca mulatta	93.22	0.00e+00	2849.00
IUUC-Meu-056467	Macropus eugenii	88.49	0.00e+00	1052.00
IUUC-Mga-059358	Meleagris gallopavo	81.14	0.00e+00	2402.00
IUUC-Mmr-060863	Microcebus murinus	94.72	0.00e+00	2822.00
IUUC-Mdo-061957	Monodelphis domestica	87.67	0.00e+00	2680.00
IUUC-Mmu-063944	Mus musculus	91.63	0.00e+00	2727.00
IUUC-Mac-065069	Musa acuminata	36.04	2.00e-08	55.80
IUUC-Mlu-068086	Myotis lucifugus	85.78	0.00e+00	2511.00
IUUC-Nle-069256	Nomascus leucogenys	92.25	0.00e+00	2808.00
IUUC-Ont-071756	Oreochromis niloticus	62.27	0.00e+00	1894.00
IUUC-Oan-073568	Ornithorhynchus anatinus	87.69	0.00e+00	2665.00
IUUC-Ocu-073961	Oryctolagus cuniculus	91.09	0.00e+00	2729.00
IUUC-Ogl-077886	Oryza glaberrima	38.83	1.00e-16	82.00
IUUC-Olo-080668	Oryza longistaminata	38.83	4.00e-16	81.60
IUUC-Opu-083164	Oryza punctata	32.13	8.00e-89	322.00
IUUC-Osa-085487	Oryza sativa	38.83	1.00e-16	82.00
IUUC-Ola-086448	Oryzias latipes	61.35	0.00e+00	1850.00
IUUC-Oga-088501	Otolemur garnettii	90.06	0.00e+00	2353.00
IUUC-Oar-090162	Ovis aries	88.62	0.00e+00	2605.00
IUUC-Ptr-090816	Pan troglodytes	93.21	0.00e+00	2857.00
IUUC-Pan-092764	Papio anubis	95.33	0.00e+00	2840.00
IUUC-Psi-093918	Pelodiscus sinensis	81.20	0.00e+00	2209.00
IUUC-Pfo-096672	Poecilia formosa	62.07	0.00e+00	1823.00
IUUC-Pab-097854	Pongo abelii	94.11	0.00e+00	2203.00
IUUC-Pca-100241	Procavia capensis	88.47	0.00e+00	1767.00
IUUC-Pva-103035	Pteropus vampyrus	85.57	0.00e+00	2213.00
IUUC-Rno-105574	Rattus norvegicus	90.19	0.00e+00	2658.00
IUUC-Sce-106207	Saccharomyces cerevisiae	35.59	7.00e-74	271.00
IUUC-Sly-111298	Solanum lycopersicum	42.66	1.00e-102	369.00
IUUC-Sar-113477	Sorex araneus	90.90	0.00e+00	2422.00
IUUC-Ssc-116132	Sus scrofa	95.13	0.00e+00	2435.00
IUUC-Tgu-117452	Taeniopygia guttata	82.26	0.00e+00	2396.00
IUUC-Tru-117561	Takifugu rubripes	63.77	0.00e+00	1734.00
IUUC-Tsy-119271	Tarsius syrichta	92.49	0.00e+00	2151.00
IUUC-Tni-119650	Tetraodon nigroviridis	65.16	0.00e+00	1753.00
IUUC-Tur-126632	Triticum urartu	32.72	1.00e-101	365.00
IUUC-Tbe-127890	Tupaia belangeri	87.46	0.00e+00	1523.00
IUUC-Ttr-128546	Tursiops truncatus	90.88	0.00e+00	2016.00
IUUC-Vpa-130432	Vicugna pacos	89.62	0.00e+00	1572.00
IUUC-Xtr-132008	Xenopus tropicalis	70.14	0.00e+00	2118.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence