iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042004

UUCD1 version

UUC-GaA-00918

Ensembl Protein ID

ENSGACP00000023219.2

UniProt Accession

G3Q029; G3Q029_GASAC

Protein Name

Katanin p80 WD40 repeat-containing subunit B1; p80 katanin

Gene Name

katnb1; KATNB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000017570.2	ENSGACT00000023264.2	ENSGACP00000023219.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-44	147.8	145	180
UBD/Beta-Prp	3.70e-61	207.3	16	262

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gHt+ v++laf +d + l+s+sdD t+k+WDl++g+
   Q: 145  GHTEAVRSLAFsPDgKWLASASDDSTVKLWDLTQGK 180
           8***********999******************997 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkf.spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
           +++h+s ++c++    +++llatg+ d ++ +w v++ +++ sl gh+++v +v+f+ +++  v gs+ + i+vwdl++ k+++tl gh
   Q: 16   FEAHSSSVSCLALgRSSGRLLATGGGDCRVNIWAVSKANCIMSLTGHKNPVECVQFNTSEEQVVAGSQSGSIRVWDLEAAKILRTLMGH 104
           577888888898889************************************************************************** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtds 182
           ++s++sl f+p gd+l+s s d  i++wd++ +  +    +gh+++v++++++pdg+ l+s+s+D+tv+lWdl +gk+++++++ ht +
   Q: 105  KSSITSLGFHPFGDFLASSSMDTNIKLWDVRRRGYVF-RYKGHTEAVRSLAFSPDGKWLASASDDSTVKLWDLTQGKMITEFKS-HTAP 191
           ******************************9866655.6********************************************9.**** PP
   S: 183  vyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsg 254
           v+ ++f++n   l+sgs d+t+klwdl++ +++ +l+g t++v+sv fs+++  l+sg+ D  +ri+  + +
   Q: 192  VNIIQFHPNEYLLASGSSDRTIKLWDLEKFTMIGSLEGDTTPVRSVFFSSDGSCLYSGATDS-LRIFGWEPD 262
           **********************************************************9875.444333444 PP

Organism

Gasterosteus aculeatus

Functional Description
(View)

Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.

Protein Sequence
(Fasta)

MAVANTTKIS WRLQEFEAHS SSVSCLALGR SSGRLLATGG GDCRVNIWAV SKANCIMSLT 60
GHKNPVECVQ FNTSEEQVVA GSQSGSIRVW DLEAAKILRT LMGHKSSITS LGFHPFGDFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGTGG CCAACACCAC CAAGATCTCA TGGAGACTGC GTAGGTTTTA TGTTCAGATT 60
GAGTTGTAAT TTGTTGTCCC TCCTGTGTCT CACAGAACTA ACTTTGTCCC CTCTGTGTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR003143--Cyt_cd1_C
IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0000922--C:spindle pole
GO:0051301--P:cell division
GO:0051013--P:microtubule severing
GO:0007067--P:mitotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000954	Aegilops tauschii	47.00	1.00e-80	295.00
IUUC-Aml-002187	Ailuropoda melanoleuca	55.43	0.00e+00	731.00
IUUC-Atr-002899	Amborella trichopoda	51.37	3.00e-95	343.00
IUUC-Apl-003305	Anas platyrhynchos	57.89	0.00e+00	768.00
IUUC-Aca-004635	Anolis carolinensis	61.43	0.00e+00	737.00
IUUC-Aly-005711	Arabidopsis lyrata	52.16	1.00e-97	351.00
IUUC-Ath-007606	Arabidopsis thaliana	52.16	9.00e-98	351.00
IUUC-Ame-010870	Astyanax mexicanus	60.00	2.00e-103	368.00
IUUC-Bta-012527	Bos taurus	57.99	0.00e+00	783.00
IUUC-Bdi-014652	Brachypodium distachyon	51.97	2.00e-98	353.00
IUUC-Bol-015242	Brassica oleracea	49.23	2.00e-96	347.00
IUUC-Bra-017390	Brassica rapa	50.79	2.00e-96	347.00
IUUC-Cja-019706	Callithrix jacchus	61.65	0.00e+00	751.00
IUUC-Cfa-020139	Canis familiaris	51.77	7.00e-139	487.00
IUUC-Cpo-021710	Cavia porcellus	61.39	0.00e+00	776.00
IUUC-Cre-022746	Chlamydomonas reinhardtii	40.00	3.00e-68	253.00
IUUC-Csa-023546	Chlorocebus sabaeus	61.54	0.00e+00	723.00
IUUC-Cin-025156	Ciona intestinalis	37.28	4.00e-134	471.00
IUUC-Csv-025962	Ciona savignyi	44.79	5.00e-80	290.00
IUUC-Dre-028215	Danio rerio	66.33	0.00e+00	888.00
IUUC-Dno-029314	Dasypus novemcinctus	61.24	0.00e+00	762.00
IUUC-Dor-030482	Dipodomys ordii	61.99	0.00e+00	790.00
IUUC-Dme-032188	Drosophila melanogaster	37.75	8.00e-60	225.00
IUUC-Eca-034143	Equus caballus	61.09	0.00e+00	770.00
IUUC-Fca-035924	Felis catus	61.99	0.00e+00	783.00
IUUC-Fal-037387	Ficedula albicollis	61.46	0.00e+00	794.00
IUUC-Gmo-038692	Gadus morhua	65.96	0.00e+00	839.00
IUUC-Gga-040597	Gallus gallus	60.57	0.00e+00	806.00
IUUC-Gma-044322	Glycine max	53.49	6.00e-98	352.00
IUUC-Ggo-044761	Gorilla gorilla	62.14	0.00e+00	748.00
IUUC-Hsa-045698	Homo sapiens	62.14	0.00e+00	766.00
IUUC-Hvu-047649	Hordeum vulgare	51.32	7.00e-98	352.00
IUUC-Itr-048697	Ictidomys tridecemlineatus	61.39	0.00e+00	763.00
IUUC-Lch-049674	Latimeria chalumnae	58.40	0.00e+00	817.00
IUUC-Lpe-051554	Leersia perrieri	50.00	2.00e-99	357.00
IUUC-Loc-052623	Lepisosteus oculatus	66.91	0.00e+00	902.00
IUUC-Laf-054587	Loxodonta africana	60.21	0.00e+00	800.00
IUUC-Mcc-055851	Macaca mulatta	62.14	0.00e+00	748.00
IUUC-Meu-056704	Macropus eugenii	61.54	0.00e+00	827.00
IUUC-Mtr-058053	Medicago truncatula	53.49	6.00e-102	365.00
IUUC-Mga-059608	Meleagris gallopavo	60.09	0.00e+00	796.00
IUUC-Mmr-061154	Microcebus murinus	61.84	0.00e+00	765.00
IUUC-Mdo-062365	Monodelphis domestica	59.34	0.00e+00	779.00
IUUC-Mmu-063754	Mus musculus	60.84	0.00e+00	775.00
IUUC-Mac-065100	Musa acuminata	52.38	1.00e-96	347.00
IUUC-Mpu-066245	Mustela putorius furo	61.99	0.00e+00	759.00
IUUC-Mlu-067692	Myotis lucifugus	61.28	0.00e+00	766.00
IUUC-Nle-070051	Nomascus leucogenys	59.91	0.00e+00	736.00
IUUC-Opr-070855	Ochotona princeps	61.54	0.00e+00	771.00
IUUC-Ont-071883	Oreochromis niloticus	78.27	0.00e+00	1071.00
IUUC-Oan-073293	Ornithorhynchus anatinus	60.67	0.00e+00	720.00
IUUC-Ocu-074644	Oryctolagus cuniculus	61.99	0.00e+00	782.00
IUUC-Oba-075448	Oryza barthii	52.30	1.00e-99	357.00
IUUC-Obr-076385	Oryza brachyantha	49.39	8.00e-99	355.00
IUUC-Ogl-077427	Oryza glaberrima	50.00	1.00e-99	358.00
IUUC-Ogu-078062	Oryza glumaepatula	47.16	1.00e-90	328.00
IUUC-Oin-079811	Oryza indica	50.47	3.00e-97	349.00
IUUC-Olo-080245	Oryza longistaminata	50.47	3.00e-97	349.00
IUUC-Ome-081239	Oryza meridionalis	50.62	4.00e-97	349.00
IUUC-Oni-082640	Oryza nivara	52.30	1.00e-99	357.00
IUUC-Opu-083748	Oryza punctata	52.30	1.00e-99	357.00
IUUC-Oru-084609	Oryza rufipogon	52.30	1.00e-99	357.00
IUUC-Osa-085801	Oryza sativa	47.99	6.00e-92	332.00
IUUC-Ola-087483	Oryzias latipes	68.73	0.00e+00	804.00
IUUC-Oga-087964	Otolemur garnettii	61.69	0.00e+00	791.00
IUUC-Oar-089483	Ovis aries	59.76	0.00e+00	752.00
IUUC-Ptr-091387	Pan troglodytes	62.14	0.00e+00	767.00
IUUC-Pan-092623	Papio anubis	62.14	0.00e+00	748.00
IUUC-Psi-093830	Pelodiscus sinensis	60.65	0.00e+00	794.00
IUUC-Pma-094135	Petromyzon marinus	42.08	1.00e-34	139.00
IUUC-Ppa-095379	Physcomitrella patens	52.36	2.00e-91	330.00
IUUC-Pfo-096755	Poecilia formosa	73.32	0.00e+00	1044.00
IUUC-Pab-097564	Pongo abelii	60.91	0.00e+00	658.00
IUUC-Pop-099149	Populus trichocarpa	52.82	3.00e-100	359.00
IUUC-Pca-100357	Procavia capensis	72.86	2.00e-94	339.00
IUUC-Ppe-101237	Prunus persica	53.16	1.00e-100	361.00
IUUC-Pva-102397	Pteropus vampyrus	58.67	0.00e+00	712.00
IUUC-Rno-105349	Rattus norvegicus	61.84	0.00e+00	790.00
IUUC-Smo-109379	Selaginella moellendorffii	51.20	1.00e-92	334.00
IUUC-Sit-110360	Setaria italica	48.55	8.00e-100	358.00
IUUC-Sly-111307	Solanum lycopersicum	51.50	3.00e-94	339.00
IUUC-Stu-112053	Solanum tuberosum	51.18	4.00e-96	345.00
IUUC-Sar-112953	Sorex araneus	60.09	1.00e-79	290.00
IUUC-Sbi-114389	Sorghum bicolor	46.64	6.00e-90	325.00
IUUC-Ssc-115949	Sus scrofa	56.85	3.00e-158	551.00
IUUC-Tgu-117461	Taeniopygia guttata	60.03	0.00e+00	806.00
IUUC-Tru-117865	Takifugu rubripes	74.32	0.00e+00	1043.00
IUUC-Tsy-119036	Tarsius syrichta	69.29	6.00e-49	188.00
IUUC-Tni-120903	Tetraodon nigroviridis	76.66	0.00e+00	1028.00
IUUC-Tca-121185	Theobroma cacao	51.50	2.00e-97	351.00
IUUC-Tae-125307	Triticum aestivum	51.97	1.00e-98	354.00
IUUC-Tur-126181	Triticum urartu	46.78	2.00e-88	320.00
IUUC-Tbe-127518	Tupaia belangeri	50.22	3.00e-111	395.00
IUUC-Ttr-128172	Tursiops truncatus	61.24	0.00e+00	757.00
IUUC-Vvi-131489	Vitis vinifera	52.26	4.00e-100	358.00
IUUC-Xtr-132915	Xenopus tropicalis	60.82	0.00e+00	797.00
IUUC-Xma-134133	Xiphophorus maculatus	73.03	0.00e+00	1034.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence