iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062729

UUCD1 version

UUC-MoD-01000

Ensembl Protein ID

ENSMODP00000001280.3

UniProt Accession

F7GI05; F7GI05_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000001075.3	ENSMODT00000001307.3	ENSMODP00000001280.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.30e-18	67.3	84	150
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.40e-14	51.4	184	214

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dvil v++++++ah++vLaa+S++F+ +f++++ esk + +ve+kd +p+  ++l++F Yt +++ n
   Q: 84   CDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESK-SFEVELKDAEPDIIEQLVEFAYTARISVN 150
           9*************************************.*************************9876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           +Nclgi  +A+++dcp+Lk  a+dfi++hF+
   Q: 184  SNCLGISVLAECLDCPELKATADDFIHQHFT 214
           8*****************************7 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAASGAEKSN KKKTEKKLAA REEAKLLASF MGVMNNMRKQ IREIKMEPLE GPRTGGEQMK 60
DSEAGDEPRS PKGQKQEGRG KTLCDVILMV QERKIPAHRV VLAAASHFFN LMFTTNMLES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCCCTTTAC TTGCCCCCGA CATTGTACAA GCCATTCACA CCAACATTCA CAAGGGCTGG 60
GAATGCTACT CCTGGTTCCA ACCAGACTAG CTCAGTGATT GATAGTCTAC TGGCAAGTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030599--KLHL7
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001981	Ailuropoda melanoleuca	92.17	0.00e+00	1144.00
IUUC-Apl-003183	Anas platyrhynchos	91.12	0.00e+00	1131.00
IUUC-Aca-004273	Anolis carolinensis	90.45	0.00e+00	1130.00
IUUC-Ame-011343	Astyanax mexicanus	77.69	0.00e+00	947.00
IUUC-Bta-012785	Bos taurus	92.01	0.00e+00	1141.00
IUUC-Cja-019038	Callithrix jacchus	91.85	0.00e+00	1165.00
IUUC-Cfa-020774	Canis familiaris	98.90	0.00e+00	1139.00
IUUC-Cpo-021716	Cavia porcellus	92.01	0.00e+00	1136.00
IUUC-Csa-023029	Chlorocebus sabaeus	92.01	0.00e+00	1142.00
IUUC-Cho-024947	Choloepus hoffmanni	79.45	0.00e+00	829.00
IUUC-Dre-028014	Danio rerio	77.36	0.00e+00	860.00
IUUC-Dno-029946	Dasypus novemcinctus	91.69	0.00e+00	1141.00
IUUC-Dor-030916	Dipodomys ordii	73.95	8.00e-169	587.00
IUUC-Dse-031294	Dothistroma septosporum	32.95	3.00e-06	44.70
IUUC-Ete-032454	Echinops telfairi	92.43	0.00e+00	632.00
IUUC-Eca-034041	Equus caballus	92.01	0.00e+00	1143.00
IUUC-Eeu-034627	Erinaceus europaeus	90.41	0.00e+00	939.00
IUUC-Fca-035854	Felis catus	92.17	0.00e+00	1144.00
IUUC-Fal-036883	Ficedula albicollis	91.36	0.00e+00	1138.00
IUUC-Gmo-038902	Gadus morhua	78.37	0.00e+00	897.00
IUUC-Gga-040866	Gallus gallus	91.12	0.00e+00	1134.00
IUUC-Gac-041428	Gasterosteus aculeatus	72.99	0.00e+00	917.00
IUUC-Ggo-044846	Gorilla gorilla	94.32	0.00e+00	1075.00
IUUC-Hsa-047034	Homo sapiens	92.01	0.00e+00	1142.00
IUUC-Itr-048807	Ictidomys tridecemlineatus	85.20	6.00e-133	466.00
IUUC-Lch-049815	Latimeria chalumnae	83.07	0.00e+00	1034.00
IUUC-Loc-052232	Lepisosteus oculatus	84.48	0.00e+00	908.00
IUUC-Laf-053520	Loxodonta africana	92.17	0.00e+00	1144.00
IUUC-Mcc-055237	Macaca mulatta	91.85	0.00e+00	1142.00
IUUC-Meu-056095	Macropus eugenii	93.55	1.00e-176	612.00
IUUC-Mga-059927	Meleagris gallopavo	91.12	0.00e+00	1134.00
IUUC-Mmr-060974	Microcebus murinus	90.68	0.00e+00	1123.00
IUUC-Mmu-063841	Mus musculus	90.42	0.00e+00	1125.00
IUUC-Mpu-066524	Mustela putorius furo	92.65	0.00e+00	1145.00
IUUC-Mlu-067215	Myotis lucifugus	91.96	0.00e+00	1139.00
IUUC-Nle-069341	Nomascus leucogenys	92.01	0.00e+00	1142.00
IUUC-Opr-070269	Ochotona princeps	91.85	0.00e+00	1140.00
IUUC-Ont-071551	Oreochromis niloticus	74.34	0.00e+00	924.00
IUUC-Oan-072718	Ornithorhynchus anatinus	98.18	0.00e+00	1134.00
IUUC-Ocu-074287	Oryctolagus cuniculus	92.01	0.00e+00	1142.00
IUUC-Ola-086718	Oryzias latipes	73.34	0.00e+00	937.00
IUUC-Oga-088757	Otolemur garnettii	91.85	0.00e+00	1140.00
IUUC-Oar-090309	Ovis aries	92.01	0.00e+00	1141.00
IUUC-Ptr-090509	Pan troglodytes	92.01	0.00e+00	1142.00
IUUC-Pan-092929	Papio anubis	92.01	0.00e+00	1142.00
IUUC-Psi-092941	Pelodiscus sinensis	91.29	0.00e+00	1135.00
IUUC-Pfo-097421	Poecilia formosa	80.22	0.00e+00	915.00
IUUC-Pab-097792	Pongo abelii	92.01	0.00e+00	1142.00
IUUC-Pca-101033	Procavia capensis	82.14	0.00e+00	827.00
IUUC-Pva-102364	Pteropus vampyrus	82.59	0.00e+00	1003.00
IUUC-Rno-105596	Rattus norvegicus	90.58	0.00e+00	1126.00
IUUC-Sha-106815	Sarcophilus harrisii	99.07	0.00e+00	1128.00
IUUC-Smo-109299	Selaginella moellendorffii	28.21	9.00e-16	79.00
IUUC-Sar-113305	Sorex araneus	91.85	0.00e+00	1144.00
IUUC-Ssc-115871	Sus scrofa	95.17	1.00e-167	582.00
IUUC-Tgu-116940	Taeniopygia guttata	91.11	0.00e+00	1131.00
IUUC-Tru-118682	Takifugu rubripes	73.63	0.00e+00	941.00
IUUC-Tsy-118787	Tarsius syrichta	97.37	0.00e+00	793.00
IUUC-Tni-120224	Tetraodon nigroviridis	74.17	0.00e+00	942.00
IUUC-Tbe-127633	Tupaia belangeri	56.43	2.00e-86	312.00
IUUC-Ttr-128500	Tursiops truncatus	98.90	0.00e+00	1141.00
IUUC-Vpa-130512	Vicugna pacos	95.04	0.00e+00	1128.00
IUUC-Xtr-131983	Xenopus tropicalis	89.97	0.00e+00	1123.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence