iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068005

Ensembl Protein ID

ENSMLUP00000016813.1

UniProt Accession

G1PZD1; G1PZD1_MYOLU

Genbank Protein ID

ENSMLUP00000016813

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02050321

Gene Name

TRIM27

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000027520.1	ENSMLUT00000025960.1	ENSMLUP00000016813.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	85.54	0.00e+00	654.00	IUUC-Hsa-046029
E3 activity/RING/RING	84.79	0.00e+00	651.00	IUUC-Mmu-064242

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

PIGVVCDRPA STARRAALEE AVPGFPEQIQ NQLDHLKRVK NLKKRHQAQG EQARAELLSL 60
TQMEREKIIW EFEQLYHSLK EQEYRLLTCL EELDLAIYNS INGATTQFSC SISQLSSLIA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCATCGGCG TGGTGTGCGA CCGCCCCGCG AGCACCGCCC GGCGGGCAGC GCTGGAGGAG 60
GCGGTGCCGG GCTTCCCGGT GAGCGGGGCG GGGGGCAGAG GCCGGAGAGC CTCCGAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom

PROSITE

PS50188--B302_SPRY

Pfam

PF13765--PRY
PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0001650--C:fibrillar center
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0030904--C:retromer complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0034314--P:Arp2/3 complex-mediated actin nucleation
GO:0045087--P:innate immune response
GO:0072643--P:interferon-gamma secretion
GO:0002820--P:negative regulation of adaptive immune response
GO:0090281--P:negative regulation of calcium ion import
GO:0045814--P:negative regulation of gene expression, epigenetic
GO:1900041--P:negative regulation of interleukin-2 secretion
GO:0006469--P:negative regulation of protein kinase activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0032720--P:negative regulation of tumor necrosis factor production
GO:1902187--P:negative regulation of viral release from host cell
GO:0032897--P:negative regulation of viral transcription
GO:0051127--P:positive regulation of actin nucleation
GO:0051091--P:positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070534--P:protein K63-linked ubiquitination
GO:0070206--P:protein trimerization
GO:0042147--P:retrograde transport, endosome to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001890	Ailuropoda melanoleuca	84.79	3.00e-178	618.00
IUUC-Bta-013520	Bos taurus	85.29	2.00e-177	615.00
IUUC-Cja-019557	Callithrix jacchus	85.04	1.00e-176	612.00
IUUC-Cfa-020583	Canis familiaris	85.29	2.00e-176	612.00
IUUC-Cpo-021738	Cavia porcellus	84.04	1.00e-174	606.00
IUUC-Csa-023502	Chlorocebus sabaeus	85.54	1.00e-177	615.00
IUUC-Cho-024563	Choloepus hoffmanni	80.72	5.00e-84	305.00
IUUC-Dno-029747	Dasypus novemcinctus	84.54	3.00e-175	608.00
IUUC-Dor-030243	Dipodomys ordii	83.46	4.00e-167	580.00
IUUC-Ete-032749	Echinops telfairi	71.07	3.00e-150	524.00
IUUC-Eca-034246	Equus caballus	87.94	3.00e-172	597.00
IUUC-Eeu-034481	Erinaceus europaeus	84.75	6.00e-159	553.00
IUUC-Fca-036152	Felis catus	87.67	3.00e-171	594.00
IUUC-Ggo-044987	Gorilla gorilla	73.72	4.00e-145	508.00
IUUC-Hsa-046029	Homo sapiens	85.54	1.00e-177	615.00
IUUC-Itr-048438	Ictidomys tridecemlineatus	85.79	6.00e-171	593.00
IUUC-Laf-054488	Loxodonta africana	85.29	1.00e-176	613.00
IUUC-Mcc-055352	Macaca mulatta	85.54	1.00e-177	615.00
IUUC-Mmr-060883	Microcebus murinus	85.29	5.00e-177	613.00
IUUC-Mmu-064242	Mus musculus	84.79	2.00e-176	611.00
IUUC-Mpu-065958	Mustela putorius furo	84.79	2.00e-176	612.00
IUUC-Nle-069710	Nomascus leucogenys	82.64	5.00e-86	311.00
IUUC-Opr-071200	Ochotona princeps	85.29	3.00e-177	614.00
IUUC-Ocu-074081	Oryctolagus cuniculus	83.38	2.00e-140	492.00
IUUC-Oga-088784	Otolemur garnettii	85.29	3.00e-177	614.00
IUUC-Oar-089433	Ovis aries	85.29	2.00e-177	615.00
IUUC-Ptr-090595	Pan troglodytes	85.54	1.00e-177	615.00
IUUC-Pan-092027	Papio anubis	85.54	1.00e-177	615.00
IUUC-Pab-098331	Pongo abelii	85.54	1.00e-177	615.00
IUUC-Pca-101091	Procavia capensis	85.29	3.00e-177	614.00
IUUC-Pva-103141	Pteropus vampyrus	87.96	2.00e-176	611.00
IUUC-Rno-105507	Rattus norvegicus	84.79	1.00e-176	612.00
IUUC-Sar-113713	Sorex araneus	76.78	3.00e-158	551.00
IUUC-Ssc-115594	Sus scrofa	85.29	2.00e-177	615.00
IUUC-Tsy-119235	Tarsius syrichta	87.43	5.00e-173	600.00
IUUC-Tbe-127796	Tupaia belangeri	85.53	3.00e-116	412.00
IUUC-Ttr-128738	Tursiops truncatus	87.67	4.00e-172	597.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence