iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-066942

Ensembl Protein ID

ENSMLUP00000007093.2

UniProt Accession

G1PA07; G1PA07_MYOLU

Genbank Protein ID

ENSMLUP00000007093

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02022543

Gene Name

HCLS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000007751.2	ENSMLUT00000007768.2	ENSMLUP00000007093.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.40e-11	42.1	450	499

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++lydy+++ +de ++   d+++ i  e  degW++g    +g  GlfP+n+v+
   Q: 450  RALYDYQGEGSDEISFDPDDIITDI--EMVDEGWWRG--RCHGHFGLFPANYVN 499
           79**********************9..9*********..8************97 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MWKSVVGHDV SVSVETQGDD WDTDPDFVND ISEKEQRWGA KTIEGSGRTE HINIHQLRNK 60
VSEEHDSLKK KELESGPKAS HGYGGRFGVE RDRMDKSAVG HEYVAEVEKH SSQTDAARGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGAAGT CTGTAGTAGG GCATGATGTA TCTGTTTCCG TGGAGACTCA AGGTGATGAC 60
TGGGACACAG ACCCTGACTT TGTGGTGAGT TTGGAAATAG CTTTGCTTGG ATAATGAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028534--HS1
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005667--C:transcription factor complex
GO:0030041--P:actin filament polymerization
GO:0071345--P:cellular response to cytokine stimulus
GO:0030218--P:erythrocyte differentiation
GO:2000107--P:negative regulation of leukocyte apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0008284--P:positive regulation of cell proliferation
GO:0030854--P:positive regulation of granulocyte differentiation
GO:0045651--P:positive regulation of macrophage differentiation
GO:0033138--P:positive regulation of peptidyl-serine phosphorylation
GO:0014068--P:positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0042531--P:positive regulation of tyrosine phosphorylation of STAT protein
GO:0030833--P:regulation of actin filament polymerization
GO:0009725--P:response to hormone

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001194	Ailuropoda melanoleuca	82.38	0.00e+00	714.00
IUUC-Bta-012591	Bos taurus	81.64	0.00e+00	651.00
IUUC-Cja-019982	Callithrix jacchus	80.04	0.00e+00	651.00
IUUC-Cfa-020262	Canis familiaris	83.30	0.00e+00	654.00
IUUC-Cpo-021362	Cavia porcellus	77.84	1.00e-178	619.00
IUUC-Csa-023911	Chlorocebus sabaeus	87.74	2.00e-163	568.00
IUUC-Dor-030437	Dipodomys ordii	71.26	4.00e-162	564.00
IUUC-Ete-033160	Echinops telfairi	71.31	6.00e-146	510.00
IUUC-Eca-033269	Equus caballus	84.83	0.00e+00	714.00
IUUC-Eeu-035032	Erinaceus europaeus	67.41	2.00e-119	422.00
IUUC-Fca-035999	Felis catus	85.66	0.00e+00	743.00
IUUC-Gga-040335	Gallus gallus	67.84	1.00e-105	377.00
IUUC-Ggo-044505	Gorilla gorilla	78.33	0.00e+00	650.00
IUUC-Hsa-046728	Homo sapiens	86.94	4.00e-161	560.00
IUUC-Itr-048592	Ictidomys tridecemlineatus	63.41	3.00e-158	551.00
IUUC-Laf-054202	Loxodonta africana	81.67	0.00e+00	669.00
IUUC-Mcc-055824	Macaca mulatta	87.50	1.00e-163	568.00
IUUC-Mmr-061281	Microcebus murinus	71.31	4.00e-159	554.00
IUUC-Mdo-062515	Monodelphis domestica	67.33	2.00e-148	518.00
IUUC-Mmu-064341	Mus musculus	81.04	0.00e+00	672.00
IUUC-Mpu-066565	Mustela putorius furo	91.19	8.00e-161	560.00
IUUC-Nle-069436	Nomascus leucogenys	81.35	0.00e+00	663.00
IUUC-Opr-070288	Ochotona princeps	72.46	2.00e-160	558.00
IUUC-Ocu-074686	Oryctolagus cuniculus	78.69	4.00e-170	590.00
IUUC-Ola-086894	Oryzias latipes	60.14	1.00e-94	340.00
IUUC-Oga-088585	Otolemur garnettii	74.31	0.00e+00	639.00
IUUC-Oar-089686	Ovis aries	82.77	0.00e+00	684.00
IUUC-Ptr-090461	Pan troglodytes	87.50	2.00e-162	565.00
IUUC-Pan-091887	Papio anubis	87.78	7.00e-165	573.00
IUUC-Psi-093785	Pelodiscus sinensis	61.88	3.00e-113	402.00
IUUC-Pab-098222	Pongo abelii	86.67	7.00e-161	560.00
IUUC-Pca-100668	Procavia capensis	80.12	0.00e+00	648.00
IUUC-Pva-102767	Pteropus vampyrus	72.17	1.00e-169	589.00
IUUC-Rno-106001	Rattus norvegicus	80.44	0.00e+00	665.00
IUUC-Sar-113338	Sorex araneus	75.16	1.00e-166	578.00
IUUC-Ssc-116027	Sus scrofa	85.03	0.00e+00	705.00
IUUC-Tgu-117472	Taeniopygia guttata	53.83	4.00e-142	497.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence