iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cme-027265

Ensembl Protein ID

CMM271CT

UniProt Accession

M1UTH6; M1UTH6_CYAM1

Genbank Protein ID

BAM81101.1

Protein Name

Ubiquitin-protein isopeptide ligase E3

Genbank Nucleotide ID

AP006495

Gene Name

CYME_CMM271C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CMM271C	CMM271CT	CMM271CT

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	7.90e-104	345.7	542	881

Active Site

Position(s)	Description	Evidence
849	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvg.....EegldlgGvtreflallskelqnpd.lglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfy 97
           s+l+++++v+fv+     E+g+d gGv++ef+++l++  ++p+ +glf+ +++++   +p+++ +  + +hl+ F flGr+lgkal+d  l+dlp++++f+
   Q: 542  SRLRENIRVKFVDeygleEAGVDGGGVFKEFMHQLIRFAFSPThYGLFKATDGGELFPNPASSVI-APSNHLEQFSFLGRILGKALYDAILVDLPIASFFL 641
           67899********9999899*****************9999988****88887766655555443.345******************************** PP
   S: 98   klllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfn 198
           ++llg + +l+dl ++dpel+++lk++++ + ++  +  l+ltf+v ++++ge+ e+eL+pgG++ipVt++N+ eY ++v++yrl+++ik q++af +Gf 
   Q: 642  RKLLGISNDLNDLRSLDPELHRNLKFLRHADPNSFGD--LCLTFTVVDNEFGEAVEKELIPGGSSIPVTWDNRLEYMHRVADYRLNRQIKAQTTAFMSGFF 740
           ****************************997666666..78888888999*************************************************** PP
   S: 199  eviplellslFteeelellicGe..eeidvedlkketkykggytedspaiqwFwevl.eefsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd. 295
           +vi+ e++++F+e el+ li+G+   +id+++l+++ +y ggy+e+s +++ Fw+v+ e++s+ er+a+LqFvT+s+r+Pl Gf++l+p  f+i+k+++d 
   Q: 741  DVIEREWIQMFNEWELRELISGDcsGKIDIDNLRSNVTYSGGYSENSGTVELFWQVVqEDLSDSERAALLQFVTSSPRAPLLGFQYLNPP-FCIQKAGDDa 840
           **********************9999*******************************999****************************98.*****99998 PP
   S: 296  drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           +r+P+++TC+n+LkLP+Ys+ e ++ekL yAi+++ gF+ls
   Q: 841  SRYPTASTCMNLLKLPPYSTREAMREKLKYAITQNFGFDLS 881
           ***********************************999985 PP

Organism

Cyanidioschyzon merolae

Protein Sequence
(Fasta)

MMQSEFSSRR ATASKLFDTG GRSAISLRGA SNVAPSRESI LLKARLERER RAAQRAQERS 60
AVAIQSLARQ YFECRRLSKI IEAELVERVA NLAQSEGPLP YDTHAAVRFV RALCFLVQLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGCAGA GTGAGTTCTC GTCGAGGAGA GCCACTGCTT CGAAGCTGTT TGACACAGGG 60
GGAAGAAGCG CTATCTCGCT CCGTGGCGCA TCTAACGTTG CTCCCTCGAG AGAGAGCATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

cme:CYME_CMM271C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	40.95	8.00e-96	343.00
IUUC-Aml-001355	Ailuropoda melanoleuca	46.62	2.00e-102	364.00
IUUC-Atr-002669	Amborella trichopoda	44.32	2.00e-104	371.00
IUUC-Apl-003731	Anas platyrhynchos	47.34	2.00e-106	378.00
IUUC-Aca-005248	Anolis carolinensis	47.34	3.00e-106	377.00
IUUC-Aly-005768	Arabidopsis lyrata	41.37	3.00e-109	387.00
IUUC-Ath-006576	Arabidopsis thaliana	40.21	4.00e-109	387.00
IUUC-Ago-007748	Ashbya gossypii	41.11	1.00e-78	285.00
IUUC-Acl-008158	Aspergillus clavatus	37.95	2.00e-72	265.00
IUUC-Afl-008398	Aspergillus flavus	36.89	3.00e-75	274.00
IUUC-Afu-008937	Aspergillus fumigatus	39.02	2.00e-75	275.00
IUUC-Ani-009252	Aspergillus nidulans	38.09	2.00e-77	281.00
IUUC-Ang-009773	Aspergillus niger	38.17	6.00e-75	273.00
IUUC-Aor-009940	Aspergillus oryzae	36.89	3.00e-75	274.00
IUUC-Ate-010395	Aspergillus terreus	37.37	2.00e-75	275.00
IUUC-Ame-010769	Astyanax mexicanus	42.13	1.00e-79	289.00
IUUC-Bgr-012269	Blumeria graminis	38.96	2.00e-73	266.00
IUUC-Bta-012841	Bos taurus	47.10	6.00e-104	369.00
IUUC-Bci-013743	Botrytis cinerea	38.33	2.00e-77	282.00
IUUC-Bdi-014123	Brachypodium distachyon	42.40	1.00e-110	392.00
IUUC-Bol-015390	Brassica oleracea	39.86	9.00e-102	362.00
IUUC-Bra-016853	Brassica rapa	40.45	4.00e-108	384.00
IUUC-Cel-018447	Caenorhabditis elegans	33.75	8.00e-82	296.00
IUUC-Cja-019743	Callithrix jacchus	47.16	7.00e-103	366.00
IUUC-Cfa-021031	Canis familiaris	46.62	7.00e-103	366.00
IUUC-Cpo-022401	Cavia porcellus	46.38	9.00e-103	365.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	45.09	1.00e-88	317.00
IUUC-Csa-024107	Chlorocebus sabaeus	46.86	1.00e-103	368.00
IUUC-Cho-024750	Choloepus hoffmanni	48.53	1.00e-90	325.00
IUUC-Cin-025750	Ciona intestinalis	35.44	1.00e-89	322.00
IUUC-Csv-026016	Ciona savignyi	37.06	5.00e-94	337.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	39.74	2.00e-83	301.00
IUUC-Cne-026841	Cryptococcus neoformans	42.22	1.00e-84	305.00
IUUC-Dre-028196	Danio rerio	47.34	8.00e-106	376.00
IUUC-Dno-029024	Dasypus novemcinctus	46.62	3.00e-103	367.00
IUUC-Dor-030938	Dipodomys ordii	35.83	2.00e-90	325.00
IUUC-Dse-031416	Dothistroma septosporum	38.14	1.00e-79	289.00
IUUC-Dme-031946	Drosophila melanogaster	44.34	2.00e-93	335.00
IUUC-Ete-033041	Echinops telfairi	41.39	4.00e-61	227.00
IUUC-Eca-033828	Equus caballus	46.86	1.00e-103	369.00
IUUC-Eeu-035201	Erinaceus europaeus	38.80	2.00e-61	228.00
IUUC-Fca-035907	Felis catus	46.62	2.00e-102	365.00
IUUC-Fal-037389	Ficedula albicollis	47.10	6.00e-106	376.00
IUUC-Fox-037788	Fusarium oxysporum	40.04	7.00e-82	296.00
IUUC-Fso-038088	Fusarium solani	39.86	4.00e-83	300.00
IUUC-Gmo-039412	Gadus morhua	36.01	2.00e-92	331.00
IUUC-Ggr-039941	Gaeumannomyces graminis	37.69	3.00e-81	294.00
IUUC-Gga-040310	Gallus gallus	47.34	7.00e-106	376.00
IUUC-Gac-042088	Gasterosteus aculeatus	36.07	1.00e-94	339.00
IUUC-Gma-042836	Glycine max	41.56	9.00e-103	365.00
IUUC-Ggo-045031	Gorilla gorilla	46.86	1.00e-103	368.00
IUUC-Hsa-045880	Homo sapiens	46.86	2.00e-103	368.00
IUUC-Hvu-047770	Hordeum vulgare	41.86	3.00e-112	397.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	41.81	5.00e-89	318.00
IUUC-Kpa-049307	Komagataella pastoris	38.73	2.00e-77	281.00
IUUC-Lch-050664	Latimeria chalumnae	36.36	3.00e-93	334.00
IUUC-Lpe-051428	Leersia perrieri	39.67	2.00e-96	344.00
IUUC-Loc-052218	Lepisosteus oculatus	47.34	4.00e-104	370.00
IUUC-Lma-053096	Leptosphaeria maculans	41.20	5.00e-84	303.00
IUUC-Laf-053902	Loxodonta africana	37.08	2.00e-95	341.00
IUUC-Mcc-055127	Macaca mulatta	46.86	2.00e-103	368.00
IUUC-Meu-056527	Macropus eugenii	31.96	7.00e-72	263.00
IUUC-Mor-057021	Magnaporthe oryzae	40.39	5.00e-73	267.00
IUUC-Mpo-057570	Magnaporthe poae	39.43	5.00e-81	293.00
IUUC-Mtr-058154	Medicago truncatula	40.93	1.00e-101	362.00
IUUC-Mla-059124	Melampsora laricipopulina	44.21	4.00e-94	335.00
IUUC-Mga-059581	Meleagris gallopavo	47.34	4.00e-106	377.00
IUUC-Mvi-060445	Microbotryum violaceum	36.63	1.00e-89	322.00
IUUC-Mmr-061360	Microcebus murinus	46.38	5.00e-103	367.00
IUUC-Mdo-062194	Monodelphis domestica	46.62	1.00e-103	369.00
IUUC-Mmu-064189	Mus musculus	46.62	2.00e-103	367.00
IUUC-Mac-065275	Musa acuminata	41.67	1.00e-109	388.00
IUUC-Mpu-066439	Mustela putorius furo	46.86	2.00e-103	367.00
IUUC-Mlu-068228	Myotis lucifugus	47.10	6.00e-104	370.00
IUUC-Nfi-068280	Neosartorya fischeri	39.23	5.00e-76	277.00
IUUC-Ncr-068869	Neurospora crassa	40.43	1.00e-84	306.00
IUUC-Nle-069687	Nomascus leucogenys	48.00	2.00e-103	368.00
IUUC-Opr-070554	Ochotona princeps	37.08	7.00e-95	339.00
IUUC-Ont-071836	Oreochromis niloticus	47.58	2.00e-105	375.00
IUUC-Oan-072800	Ornithorhynchus anatinus	47.58	2.00e-106	378.00
IUUC-Ocu-074587	Oryctolagus cuniculus	46.86	2.00e-103	367.00
IUUC-Oba-075006	Oryza barthii	42.14	6.00e-110	389.00
IUUC-Obr-076133	Oryza brachyantha	41.95	3.00e-110	390.00
IUUC-Ogl-077003	Oryza glaberrima	42.14	6.00e-110	389.00
IUUC-Ogu-078947	Oryza glumaepatula	41.88	6.00e-109	386.00
IUUC-Oin-079407	Oryza indica	39.19	1.00e-97	348.00
IUUC-Olo-080475	Oryza longistaminata	42.14	3.00e-110	390.00
IUUC-Ome-081342	Oryza meridionalis	39.18	2.00e-95	341.00
IUUC-Oni-082385	Oryza nivara	41.88	6.00e-109	386.00
IUUC-Opu-083176	Oryza punctata	40.55	7.00e-106	376.00
IUUC-Oru-084554	Oryza rufipogon	39.44	9.00e-97	346.00
IUUC-Osa-085355	Oryza sativa	42.14	3.00e-110	390.00
IUUC-Ola-087209	Oryzias latipes	47.10	8.00e-107	379.00
IUUC-Olu-087699	Ostreococcus lucimarinus	46.63	2.00e-89	320.00
IUUC-Oga-088776	Otolemur garnettii	46.62	1.00e-103	368.00
IUUC-Oar-089441	Ovis aries	47.10	4.00e-104	370.00
IUUC-Ptr-091273	Pan troglodytes	46.86	1.00e-103	369.00
IUUC-Pan-091981	Papio anubis	46.86	2.00e-103	368.00
IUUC-Psi-093251	Pelodiscus sinensis	36.20	3.00e-83	301.00
IUUC-Pma-094738	Petromyzon marinus	43.06	1.00e-103	368.00
IUUC-Pno-095132	Phaeosphaeria nodorum	37.50	1.00e-57	216.00
IUUC-Ppa-095682	Physcomitrella patens	43.85	3.00e-117	414.00
IUUC-Pfo-097511	Poecilia formosa	48.07	1.00e-107	382.00
IUUC-Pab-098634	Pongo abelii	43.88	2.00e-92	331.00
IUUC-Pop-098928	Populus trichocarpa	40.37	4.00e-96	343.00
IUUC-Pca-100987	Procavia capensis	47.30	3.00e-98	350.00
IUUC-Ppe-102040	Prunus persica	40.74	6.00e-98	350.00
IUUC-Pva-102887	Pteropus vampyrus	41.24	3.00e-91	327.00
IUUC-Pgr-103513	Puccinia graminis	47.26	2.00e-97	348.00
IUUC-Ptt-103967	Puccinia triticina	45.27	4.00e-88	317.00
IUUC-Pte-104105	Pyrenophora teres	39.32	2.00e-80	292.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	39.10	3.00e-80	291.00
IUUC-Rno-106028	Rattus norvegicus	34.81	1.00e-79	289.00
IUUC-Sce-106446	Saccharomyces cerevisiae	40.78	2.00e-75	274.00
IUUC-Sha-107108	Sarcophilus harrisii	43.65	2.00e-92	332.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	41.28	1.00e-90	325.00
IUUC-Spo-108097	Schizosaccharomyces pombe	41.09	3.00e-86	311.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	39.61	3.00e-76	278.00
IUUC-Smo-108853	Selaginella moellendorffii	41.96	4.00e-109	387.00
IUUC-Sit-110457	Setaria italica	43.12	2.00e-105	374.00
IUUC-Sly-111362	Solanum lycopersicum	42.22	1.00e-106	379.00
IUUC-Sar-113687	Sorex araneus	44.14	7.00e-65	239.00
IUUC-Sbi-113882	Sorghum bicolor	42.59	8.00e-104	369.00
IUUC-Sre-115038	Sporisorium reilianum	46.62	7.00e-96	343.00
IUUC-Ssc-116103	Sus scrofa	36.72	2.00e-94	338.00
IUUC-Tgu-116729	Taeniopygia guttata	47.10	3.00e-105	374.00
IUUC-Tru-118068	Takifugu rubripes	47.58	2.00e-106	377.00
IUUC-Tsy-118942	Tarsius syrichta	50.58	7.00e-67	246.00
IUUC-Tni-120732	Tetraodon nigroviridis	46.38	9.00e-100	356.00
IUUC-Tca-121737	Theobroma cacao	40.95	7.00e-108	382.00
IUUC-Tre-121892	Trichoderma reesei	40.45	1.00e-82	299.00
IUUC-Tvi-122354	Trichoderma virens	41.07	3.00e-85	308.00
IUUC-Tae-125466	Triticum aestivum	41.86	3.00e-112	397.00
IUUC-Tur-126086	Triticum urartu	40.95	8.00e-96	343.00
IUUC-Tme-127102	Tuber melanosporum	38.46	9.00e-82	296.00
IUUC-Tbe-127351	Tupaia belangeri	45.81	1.00e-86	312.00
IUUC-Ttr-129061	Tursiops truncatus	47.30	8.00e-98	349.00
IUUC-Uma-129343	Ustilago maydis	46.86	9.00e-100	356.00
IUUC-Vda-129748	Verticillium dahliae	39.04	1.00e-76	279.00
IUUC-Vvi-131234	Vitis vinifera	41.85	2.00e-103	368.00
IUUC-Xtr-132094	Xenopus tropicalis	47.58	3.00e-106	377.00
IUUC-Xma-133923	Xiphophorus maculatus	43.58	1.00e-107	382.00
IUUC-Yli-134496	Yarrowia lipolytica	38.02	2.00e-79	288.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence