iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.20e-19	70.8	31	98
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.60e-09	34.5	131	161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +D++l+v+g+ef++hk vLa++Ss+F+a+f ++l+esk +  v+++ v++ +++ ++ + Ytg l +n+
   Q: 31   TDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESK-QTHVHLRNVDAAALQMIITYAYTGNLAIND 98
           79************************************.*************************99885 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           eNc+ +l+fAdl++c++Lk++a +++++ F+
   Q: 131  ENCVRLLSFADLFSCEELKQSAKRMVEHKFT 161
           9***************************996 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSTQEERQIN TEYAVSLLEQ LKLFYEQQLF TDIVLIVEGT EFPCHKMVLA TCSSYFRAMF 60
MSGLSESKQT HVHLRNVDAA ALQMIITYAY TGNLAINDST VEQLYETACF LQVEDVLQRC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGCTGTGC GTGCGGCCGC GTGAGTGCAG CCCGGCGGAG CGGCGCGGTG AGCTGGGCGG 60
CCGGGGCCGA GGTGAGCCCG GTCGGACGCG AGGTGGGCGG CCTTTGTGGG CCGGGGCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

rno:312372

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001980	Ailuropoda melanoleuca	98.88	0.00e+00	1231.00
IUUC-Apl-003925	Anas platyrhynchos	95.22	2.00e-173	601.00
IUUC-Aca-004617	Anolis carolinensis	91.97	0.00e+00	1134.00
IUUC-Ame-011278	Astyanax mexicanus	78.91	0.00e+00	1022.00
IUUC-Cja-019947	Callithrix jacchus	98.88	0.00e+00	1229.00
IUUC-Cfa-020881	Canis familiaris	98.25	0.00e+00	1224.00
IUUC-Cpo-022211	Cavia porcellus	98.72	0.00e+00	1228.00
IUUC-Csa-023683	Chlorocebus sabaeus	98.72	0.00e+00	1228.00
IUUC-Cho-024791	Choloepus hoffmanni	98.28	0.00e+00	1006.00
IUUC-Dre-028364	Danio rerio	78.75	0.00e+00	1030.00
IUUC-Dno-028875	Dasypus novemcinctus	98.88	0.00e+00	1268.00
IUUC-Dor-030193	Dipodomys ordii	96.64	0.00e+00	1021.00
IUUC-Ete-033079	Echinops telfairi	96.91	0.00e+00	989.00
IUUC-Eca-033435	Equus caballus	98.88	0.00e+00	1230.00
IUUC-Eeu-035017	Erinaceus europaeus	86.36	0.00e+00	1127.00
IUUC-Fca-036446	Felis catus	98.56	0.00e+00	1226.00
IUUC-Fal-037576	Ficedula albicollis	94.38	0.00e+00	1158.00
IUUC-Gmo-038975	Gadus morhua	78.85	0.00e+00	1060.00
IUUC-Gga-041077	Gallus gallus	94.06	0.00e+00	1183.00
IUUC-Gac-041424	Gasterosteus aculeatus	80.38	0.00e+00	1086.00
IUUC-Ggo-045425	Gorilla gorilla	90.69	0.00e+00	1112.00
IUUC-Hsa-046816	Homo sapiens	98.72	0.00e+00	1228.00
IUUC-Itr-048782	Ictidomys tridecemlineatus	98.72	0.00e+00	1226.00
IUUC-Lch-049911	Latimeria chalumnae	88.28	0.00e+00	1130.00
IUUC-Loc-051799	Lepisosteus oculatus	81.28	0.00e+00	1076.00
IUUC-Laf-054074	Loxodonta africana	99.36	0.00e+00	1230.00
IUUC-Mga-059314	Meleagris gallopavo	93.90	0.00e+00	1181.00
IUUC-Mmr-061398	Microcebus murinus	98.77	2.00e-180	624.00
IUUC-Mdo-062664	Monodelphis domestica	94.38	0.00e+00	1181.00
IUUC-Mmu-064390	Mus musculus	99.68	0.00e+00	1238.00
IUUC-Mpu-065709	Mustela putorius furo	99.04	0.00e+00	1231.00
IUUC-Mlu-067793	Myotis lucifugus	97.24	0.00e+00	1180.00
IUUC-Nle-070079	Nomascus leucogenys	98.72	0.00e+00	1228.00
IUUC-Opr-070899	Ochotona princeps	99.20	0.00e+00	1233.00
IUUC-Ont-071857	Oreochromis niloticus	80.38	0.00e+00	1065.00
IUUC-Oan-073592	Ornithorhynchus anatinus	86.49	0.00e+00	1067.00
IUUC-Ocu-073873	Oryctolagus cuniculus	98.54	0.00e+00	783.00
IUUC-Ola-087086	Oryzias latipes	80.06	0.00e+00	1072.00
IUUC-Oga-088930	Otolemur garnettii	98.56	0.00e+00	1226.00
IUUC-Oar-089834	Ovis aries	98.56	0.00e+00	1228.00
IUUC-Ptr-090654	Pan troglodytes	98.56	0.00e+00	1226.00
IUUC-Pan-092621	Papio anubis	98.72	0.00e+00	1228.00
IUUC-Psi-093224	Pelodiscus sinensis	93.74	0.00e+00	1192.00
IUUC-Pfo-096292	Poecilia formosa	80.70	0.00e+00	1088.00
IUUC-Pab-098136	Pongo abelii	97.59	0.00e+00	1213.00
IUUC-Pca-100915	Procavia capensis	96.87	0.00e+00	733.00
IUUC-Pva-102336	Pteropus vampyrus	98.39	0.00e+00	1223.00
IUUC-Sha-107251	Sarcophilus harrisii	94.06	0.00e+00	1177.00
IUUC-Sar-113206	Sorex araneus	96.79	0.00e+00	1197.00
IUUC-Ssc-115475	Sus scrofa	98.24	0.00e+00	1221.00
IUUC-Tru-118290	Takifugu rubripes	80.06	0.00e+00	1057.00
IUUC-Tsy-119202	Tarsius syrichta	97.87	2.00e-148	519.00
IUUC-Tni-119756	Tetraodon nigroviridis	79.74	0.00e+00	1049.00
IUUC-Tbe-127231	Tupaia belangeri	95.83	0.00e+00	1179.00
IUUC-Ttr-128297	Tursiops truncatus	98.56	0.00e+00	1228.00
IUUC-Vpa-130190	Vicugna pacos	93.68	0.00e+00	778.00
IUUC-Xtr-132385	Xenopus tropicalis	84.91	0.00e+00	1082.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence