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Tag Content
UUCD2 ID IUUC-Itr-049041
UUCD1 version UUC-SpT-00729
Ensembl Protein ID ENSSTOP00000012765.2
UniProt Accession I3MMJ9; I3MMJ9_ICTTR
Genbank Protein ID ENSSTOP00000012765
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AGTP01063453
Gene Name USP33
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSTOG00000014241.2 ENSSTOT00000014250.2 ENSSTOP00000012765.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.20e-113 379.7 153 683
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tGlkN+gNtCYmN++LQ+Lsn+p+l++++l+     +   +++++k +++ks+ kl++elw ks+ ++v p++l++ +k++++ f+gy+
   Q: 153  TGLKNIGNTCYMNAALQALSNCPPLTQFFLD-----CGGLARTDKKPAICKSYLKLMTELWhKSRPGSVVPTNLFQGIKTVNPTFRGYS 236
           7******************************.....999999*******************99************************** PP
   S: 89   qqDaqEflaflldqleeelkk........eknkpkeeeeeedkselsde........................................ 129
           qqDaqEfl++l+d l+eelk+         ++ ++ee++ee+ks+++ +                                        
   Q: 237  QQDAQEFLRCLMDLLHEELKEqvmeveedPQTITTEETMEEEKSQSDVDfqscescsssdktenengsrngfsednnettmliqddenn 325
           *******************888998887666666666666666666666999************************************* PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 326  semskdwqkekmcnkinkvnsegeldknrdsvsetldlnnqetvkvqihgrtseyvtdvhlndlstpqslpsnegvnprlsasppksgn 414
           ***************************************************************************************** PP
   S: 130  .................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke................ 185
                            +++k++kk++s+isd+F+g++ s+++cl+cd+vs++ e+f+dlslp+pgke+ +k+                
   Q: 415  lwpglasthkkaqsaspKRKKQHKKYRSVISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLhstshptsivkagscg 503
           *****************9**************************************************99888**************** PP
   S: 186  .................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfse 241
                                            +lqdcL++f++++el+g+n+y+cekckk+++ +k +k++k+Pe+L++hLkRf  ++
   Q: 504  eayapqgwiaffmeyvkrfvvscvpswfwgpvvTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQKFPEILCIHLKRF--RH 590
           *************************************************************************************..99 PP
   S: 242  eqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgs 328
           e ++++ki+++v+fple Ldl+pf+++++ +q   ++Y+L++v++H+G++ssGHY+ay++n+ ++ W++fdD++Vtev+e++v++   +
   Q: 591  ELMFSTKISTHVSFPLEgLDLQPFLAKDSPTQ--IVTYDLLSVICHHGTASSGHYIAYCRNNLNNlWYEFDDQSVTEVSESTVQN---A 674
           99*************************88887..9**************************88889*******************...* PP
   S: 329  taYvlfYkr 337
           +aYvlfY++
   Q: 675  EAYVLFYRK 683
           *******98 PP
   
Organism Ictidomys tridecemlineatus
Protein Sequence
(Fasta)
MSAFRNHCPH LDSVGEITKE DLIQKSHGTC QDCKVRGPNL WACLENRCSY VGCGETQDHS 60
TIHSQETKHY LTVNLTTLRV WCYACSKEVF LDRKLGTQPS LPHGRQPQQT QENSVQDFKI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Itr-049041|DUB,USP|Ictidomys tridecemlineatus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTCAGCTT TTCGAAATCA TTGTCCACAT TTGGATTCAG TTGGTGAAAT AACAAAAGAA 60
GATTTGATAC AAAAATCTCA TGTAAGATGT TAATCTTTCT TAAAAAAAAA TCATACTTGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Itr-049041|DUB,USP|Ictidomys tridecemlineatus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF06337--DUSP
PF00443--UCH
PF02148--zf-UBP
SMART

SM00695--DUSP
SM00290--ZnF_UBP
Gene Ontology

GO:0005776--C:autophagosome
GO:0044297--C:cell body
GO:0005813--C:centrosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0007411--P:axon guidance
GO:0016477--P:cell migration
GO:0009267--P:cellular response to starvation
GO:0051298--P:centrosome duplication
GO:0032091--P:negative regulation of protein binding
GO:0032092--P:positive regulation of protein binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0050821--P:protein stabilization
GO:0010506--P:regulation of autophagy
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001742 Ailuropoda melanoleuca 96.62 0.00e+00 1758.00
IUUC-Apl-003987 Anas platyrhynchos 82.39 0.00e+00 1470.00
IUUC-Aca-004713 Anolis carolinensis 77.35 0.00e+00 1405.00
IUUC-Bta-013132 Bos taurus 96.06 0.00e+00 1749.00
IUUC-Cja-018811 Callithrix jacchus 96.27 0.00e+00 1766.00
IUUC-Cfa-021158 Canis familiaris 96.18 0.00e+00 1748.00
IUUC-Cpo-021910 Cavia porcellus 89.17 0.00e+00 1567.00
IUUC-Csa-023130 Chlorocebus sabaeus 96.82 0.00e+00 1768.00
IUUC-Cho-024383 Choloepus hoffmanni 78.92 0.00e+00 646.00
IUUC-Dre-028639 Danio rerio 70.80 0.00e+00 1249.00
IUUC-Dno-029416 Dasypus novemcinctus 94.09 0.00e+00 1697.00
IUUC-Dme-031837 Drosophila melanogaster 44.67 1.00e-130 460.00
IUUC-Ete-032994 Echinops telfairi 78.94 0.00e+00 835.00
IUUC-Eca-034248 Equus caballus 96.50 0.00e+00 1759.00
IUUC-Eeu-035357 Erinaceus europaeus 77.63 0.00e+00 1292.00
IUUC-Fca-036013 Felis catus 93.88 0.00e+00 1693.00
IUUC-Fal-037509 Ficedula albicollis 81.71 0.00e+00 1470.00
IUUC-Gmo-038944 Gadus morhua 66.20 0.00e+00 1192.00
IUUC-Gga-040647 Gallus gallus 81.40 0.00e+00 1453.00
IUUC-Gac-041752 Gasterosteus aculeatus 69.89 0.00e+00 1256.00
IUUC-Hsa-045694 Homo sapiens 96.27 0.00e+00 1751.00
IUUC-Lch-050400 Latimeria chalumnae 70.37 0.00e+00 1251.00
IUUC-Loc-052616 Lepisosteus oculatus 71.68 0.00e+00 1310.00
IUUC-Laf-053493 Loxodonta africana 95.41 0.00e+00 1743.00
IUUC-Mcc-055542 Macaca mulatta 97.04 0.00e+00 1772.00
IUUC-Meu-056645 Macropus eugenii 73.96 0.00e+00 1292.00
IUUC-Mga-060019 Meleagris gallopavo 82.22 0.00e+00 1255.00
IUUC-Mmr-061241 Microcebus murinus 93.20 0.00e+00 1710.00
IUUC-Mmu-063786 Mus musculus 92.65 0.00e+00 1674.00
IUUC-Mpu-065772 Mustela putorius furo 96.40 0.00e+00 1464.00
IUUC-Mlu-067732 Myotis lucifugus 95.09 0.00e+00 1734.00
IUUC-Nle-069528 Nomascus leucogenys 95.29 0.00e+00 1766.00
IUUC-Opr-070606 Ochotona princeps 90.79 0.00e+00 1565.00
IUUC-Ont-071495 Oreochromis niloticus 70.90 0.00e+00 1263.00
IUUC-Oan-073695 Ornithorhynchus anatinus 85.20 0.00e+00 1034.00
IUUC-Ocu-074457 Oryctolagus cuniculus 92.83 0.00e+00 1707.00
IUUC-Ola-086739 Oryzias latipes 69.01 0.00e+00 1283.00
IUUC-Oga-088720 Otolemur garnettii 95.73 0.00e+00 1755.00
IUUC-Oar-089921 Ovis aries 95.95 0.00e+00 1750.00
IUUC-Ptr-090526 Pan troglodytes 96.38 0.00e+00 1755.00
IUUC-Pan-092396 Papio anubis 96.72 0.00e+00 1763.00
IUUC-Psi-092971 Pelodiscus sinensis 82.95 0.00e+00 1538.00
IUUC-Pma-094389 Petromyzon marinus 59.68 9.00e-86 309.00
IUUC-Pfo-097415 Poecilia formosa 69.97 0.00e+00 1266.00
IUUC-Pab-098740 Pongo abelii 96.60 0.00e+00 1786.00
IUUC-Pca-100598 Procavia capensis 83.46 0.00e+00 904.00
IUUC-Pva-102820 Pteropus vampyrus 91.92 0.00e+00 1462.00
IUUC-Rno-104894 Rattus norvegicus 93.08 0.00e+00 1709.00
IUUC-Sce-106176 Saccharomyces cerevisiae 32.35 2.00e-25 110.00
IUUC-Sha-107244 Sarcophilus harrisii 77.83 0.00e+00 1389.00
IUUC-Sar-113665 Sorex araneus 93.42 0.00e+00 1733.00
IUUC-Ssc-115793 Sus scrofa 93.76 0.00e+00 1678.00
IUUC-Tgu-117487 Taeniopygia guttata 82.94 0.00e+00 1442.00
IUUC-Tru-117694 Takifugu rubripes 68.38 0.00e+00 1273.00
IUUC-Tsy-119598 Tarsius syrichta 83.85 0.00e+00 1452.00
IUUC-Tni-120189 Tetraodon nigroviridis 67.46 0.00e+00 1197.00
IUUC-Tbe-128125 Tupaia belangeri 86.19 1.00e-110 394.00
IUUC-Ttr-128269 Tursiops truncatus 92.65 0.00e+00 1621.00
IUUC-Vpa-130598 Vicugna pacos 94.31 0.00e+00 1708.00
IUUC-Xtr-132044 Xenopus tropicalis 74.32 0.00e+00 1311.00
Created Date 25-Jun-2017

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