iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091407

UUCD1 version

UUC-PaT-00083

Ensembl Protein ID

ENSPTRP00000000457.4

UniProt Accession

H2PY68; H2PY68_PANTR

Genbank Protein ID

JAA32788.1; JAA43557.1

Protein Name

Ubiquitin protein ligase E3 component n-recognin 4

Genbank Nucleotide ID

AACZ03008262; GABE01001182

Gene Name

UBR4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000000257.6	ENSPTRT00000000526.4	ENSPTRP00000000457.4

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/N-recognin/UBR-box	99.90	0.00e+00	9784.00	IUUC-Hsa-046955

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MATSGGEEAA AAAPAPGTPA TGADTTPGWE VAVRPLLSAS YSAFEMKELP QLVASVIESE 60
SEILHHEKQY EPFYSSFVAL STHYITTVCS LIPRNQLQSV AAACKVLIEF SLLRLENPDE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGATGGCG ACGAGCGGCG GCGAAGAGGC GGCGGCAGCG GCTCCGGCGC CCGGGACCCC 60
GGCAACGGGG GCGGACACGA CCCCGGGCTG GGAGGTGGCT GTGCGGCCCC TGCTGTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025704--E3_Ub_ligase_UBR4
IPR017986--WD40_repeat_dom
IPR003126--Znf_UBR

PROSITE

PS51157--ZF_UBR

Pfam

PF13764--E3_UbLigase_R4
PF02207--zf-UBR

SMART

SM00396--ZnF_UBR1

Gene Ontology

GO:0005813--C:centrosome
GO:0005829--C:cytosol
GO:0016020--C:membrane
GO:0005654--C:nucleoplasm
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000915	Aegilops tauschii	31.66	0.00e+00	974.00
IUUC-Aml-001346	Ailuropoda melanoleuca	98.06	0.00e+00	9624.00
IUUC-Atr-002587	Amborella trichopoda	35.17	2.00e-147	518.00
IUUC-Apl-003678	Anas platyrhynchos	91.68	0.00e+00	5670.00
IUUC-Aca-004517	Anolis carolinensis	91.54	0.00e+00	932.00
IUUC-Aly-006117	Arabidopsis lyrata	32.33	0.00e+00	899.00
IUUC-Ath-007289	Arabidopsis thaliana	31.66	0.00e+00	900.00
IUUC-Ame-011965	Astyanax mexicanus	82.75	0.00e+00	4742.00
IUUC-Bta-012498	Bos taurus	96.88	0.00e+00	9498.00
IUUC-Bdi-014555	Brachypodium distachyon	30.82	0.00e+00	974.00
IUUC-Bol-015522	Brassica oleracea	31.50	0.00e+00	923.00
IUUC-Bra-017090	Brassica rapa	31.51	0.00e+00	856.00
IUUC-Cel-018504	Caenorhabditis elegans	25.51	2.00e-161	564.00
IUUC-Cja-018983	Callithrix jacchus	99.44	0.00e+00	9755.00
IUUC-Cfa-020612	Canis familiaris	98.18	0.00e+00	9665.00
IUUC-Cpo-021700	Cavia porcellus	97.87	0.00e+00	9648.00
IUUC-Csa-023771	Chlorocebus sabaeus	99.67	0.00e+00	9728.00
IUUC-Cho-024474	Choloepus hoffmanni	91.21	0.00e+00	4825.00
IUUC-Cin-025247	Ciona intestinalis	58.16	0.00e+00	1038.00
IUUC-Csv-026255	Ciona savignyi	58.13	0.00e+00	1063.00
IUUC-Dre-028796	Danio rerio	84.87	0.00e+00	5117.00
IUUC-Dno-030056	Dasypus novemcinctus	97.75	0.00e+00	9621.00
IUUC-Dor-030711	Dipodomys ordii	94.60	0.00e+00	6918.00
IUUC-Dme-032113	Drosophila melanogaster	44.44	0.00e+00	1959.00
IUUC-Ete-032334	Echinops telfairi	89.34	0.00e+00	4781.00
IUUC-Eca-033327	Equus caballus	98.29	0.00e+00	9685.00
IUUC-Eeu-034698	Erinaceus europaeus	85.75	0.00e+00	1220.00
IUUC-Fca-035430	Felis catus	97.48	0.00e+00	9512.00
IUUC-Fal-037566	Ficedula albicollis	91.14	0.00e+00	5615.00
IUUC-Gmo-038674	Gadus morhua	83.72	0.00e+00	8058.00
IUUC-Ggr-039732	Gaeumannomyces graminis	42.86	2.40e-01	30.00
IUUC-Gga-040641	Gallus gallus	92.78	0.00e+00	9249.00
IUUC-Gac-041870	Gasterosteus aculeatus	84.25	0.00e+00	8362.00
IUUC-Gma-042722	Glycine max	31.36	0.00e+00	948.00
IUUC-Ggo-045360	Gorilla gorilla	99.59	0.00e+00	9784.00
IUUC-Hsa-046955	Homo sapiens	99.90	0.00e+00	9784.00
IUUC-Hvu-047255	Hordeum vulgare	31.52	0.00e+00	967.00
IUUC-Itr-048714	Ictidomys tridecemlineatus	95.81	0.00e+00	3932.00
IUUC-Lch-049893	Latimeria chalumnae	81.25	0.00e+00	5002.00
IUUC-Lpe-050948	Leersia perrieri	31.40	0.00e+00	895.00
IUUC-Loc-052019	Lepisosteus oculatus	83.80	0.00e+00	8200.00
IUUC-Laf-054238	Loxodonta africana	97.48	0.00e+00	9550.00
IUUC-Mcc-054905	Macaca mulatta	99.65	0.00e+00	9760.00
IUUC-Meu-056297	Macropus eugenii	87.45	0.00e+00	8469.00
IUUC-Mtr-058169	Medicago truncatula	32.19	0.00e+00	943.00
IUUC-Mga-059621	Meleagris gallopavo	92.15	0.00e+00	9210.00
IUUC-Mmr-061395	Microcebus murinus	99.40	0.00e+00	3004.00
IUUC-Mdo-063037	Monodelphis domestica	92.29	0.00e+00	4633.00
IUUC-Mmu-063200	Mus musculus	96.96	0.00e+00	9461.00
IUUC-Mac-065267	Musa acuminata	31.10	0.00e+00	883.00
IUUC-Mpu-066639	Mustela putorius furo	98.29	0.00e+00	9642.00
IUUC-Mlu-067172	Myotis lucifugus	97.33	0.00e+00	9639.00
IUUC-Nle-069162	Nomascus leucogenys	99.64	0.00e+00	8513.00
IUUC-Opr-070567	Ochotona princeps	94.33	0.00e+00	3532.00
IUUC-Ont-072364	Oreochromis niloticus	82.56	0.00e+00	4999.00
IUUC-Oan-072804	Ornithorhynchus anatinus	84.05	0.00e+00	2016.00
IUUC-Ocu-074637	Oryctolagus cuniculus	97.80	0.00e+00	9626.00
IUUC-Oba-075215	Oryza barthii	34.25	0.00e+00	828.00
IUUC-Obr-076704	Oryza brachyantha	31.89	0.00e+00	946.00
IUUC-Ogl-077593	Oryza glaberrima	36.08	0.00e+00	651.00
IUUC-Ogu-078732	Oryza glumaepatula	31.47	0.00e+00	896.00
IUUC-Oin-079805	Oryza indica	32.74	0.00e+00	739.00
IUUC-Olo-080261	Oryza longistaminata	34.30	0.00e+00	833.00
IUUC-Ome-081392	Oryza meridionalis	33.91	0.00e+00	870.00
IUUC-Oni-082086	Oryza nivara	34.02	0.00e+00	833.00
IUUC-Opu-083535	Oryza punctata	34.08	0.00e+00	837.00
IUUC-Oru-084735	Oryza rufipogon	34.02	0.00e+00	832.00
IUUC-Ola-086799	Oryzias latipes	84.11	0.00e+00	8252.00
IUUC-Olu-087777	Ostreococcus lucimarinus	27.28	1.00e-85	313.00
IUUC-Oga-088126	Otolemur garnettii	95.60	0.00e+00	1554.00
IUUC-Oar-090428	Ovis aries	95.59	0.00e+00	9305.00
IUUC-Pan-091777	Papio anubis	99.19	0.00e+00	9748.00
IUUC-Psi-093587	Pelodiscus sinensis	92.41	0.00e+00	9284.00
IUUC-Ppa-095781	Physcomitrella patens	32.25	0.00e+00	983.00
IUUC-Pfo-097449	Poecilia formosa	84.31	0.00e+00	8370.00
IUUC-Pab-098450	Pongo abelii	98.45	0.00e+00	9626.00
IUUC-Pop-100041	Populus trichocarpa	32.12	0.00e+00	913.00
IUUC-Pca-100663	Procavia capensis	90.73	0.00e+00	2871.00
IUUC-Ppe-101386	Prunus persica	32.41	0.00e+00	829.00
IUUC-Pva-102701	Pteropus vampyrus	98.11	0.00e+00	4099.00
IUUC-Ptt-103987	Puccinia triticina	23.66	6.00e-03	33.90
IUUC-Rno-105367	Rattus norvegicus	96.18	0.00e+00	5809.00
IUUC-Sha-107490	Sarcophilus harrisii	92.73	0.00e+00	5708.00
IUUC-Smo-109103	Selaginella moellendorffii	33.26	0.00e+00	911.00
IUUC-Sit-110670	Setaria italica	31.77	0.00e+00	958.00
IUUC-Sly-110952	Solanum lycopersicum	32.26	0.00e+00	901.00
IUUC-Stu-112624	Solanum tuberosum	31.68	2.00e-157	550.00
IUUC-Sar-113180	Sorex araneus	90.93	0.00e+00	4269.00
IUUC-Sbi-114596	Sorghum bicolor	31.93	0.00e+00	939.00
IUUC-Ssc-115377	Sus scrofa	99.26	0.00e+00	3002.00
IUUC-Tgu-117330	Taeniopygia guttata	90.25	0.00e+00	5595.00
IUUC-Tru-117635	Takifugu rubripes	83.55	0.00e+00	8289.00
IUUC-Tsy-119551	Tarsius syrichta	90.69	0.00e+00	4617.00
IUUC-Tni-119727	Tetraodon nigroviridis	83.32	0.00e+00	8265.00
IUUC-Tca-121017	Theobroma cacao	31.88	0.00e+00	943.00
IUUC-Tae-122892	Triticum aestivum	35.37	2.00e-25	109.00
IUUC-Tur-126292	Triticum urartu	32.68	0.00e+00	968.00
IUUC-Ttr-128332	Tursiops truncatus	96.77	0.00e+00	8479.00
IUUC-Vpa-130615	Vicugna pacos	91.92	0.00e+00	2622.00
IUUC-Vvi-131435	Vitis vinifera	34.16	0.00e+00	822.00
IUUC-Xtr-132130	Xenopus tropicalis	90.36	0.00e+00	2113.00
IUUC-Xma-133859	Xiphophorus maculatus	82.42	0.00e+00	5072.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence