iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133060

Ensembl Protein ID

ENSXMAP00000016470.1

UniProt Accession

M4APS5; M4APS5_XIPMA

Genbank Protein ID

ENSXMAP00000016470

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AGAJ01002407

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000016422.1	ENSXMAT00000016494.1	ENSXMAP00000016470.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	8.50e-31	106.0	391	440

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrsk 54
           k+C  C+++ged+ ++++C+ C++ +H  Cl+++  ++lp++  w C++Cr +
   Q: 391  KICQTCKNPGEDT-KMLVCDMCDKGYHTFCLQPA-IDSLPTNG-WRCKNCRVC 440
           79*********87.6*******************.99*****8.******965 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MSSEDKTVET SDQGPSPSSS SVGTTSTGSP ANADKRPRGR PRKDAAAAAV LPQLPPLSTA 60
KSKKKGRTRG RVVVDEEDSM DGTEITETTD PQDAETQIQP VETVEVETTE APEEEKRSSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGCCACCGT TATAGAGTAC ACCGAAGCGT CATCTTCAAC TTGGTTTTGT CATGTTTATT 60
GCTGATATTT CTACTCGGTC CGTGGGGCAG ACTGAGTGTC ATTTTTAGGG AAGCCAATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR000637--HMGI/Y_DNA-bd_CS
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS00354--HMGI_Y
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00184--RING
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0018024--F:histone-lysine N-methyltransferase activity
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002314	Ailuropoda melanoleuca	46.20	0.00e+00	1335.00
IUUC-Apl-003311	Anas platyrhynchos	45.53	0.00e+00	1667.00
IUUC-Aca-004705	Anolis carolinensis	46.70	0.00e+00	2579.00
IUUC-Bta-012322	Bos taurus	46.94	0.00e+00	1341.00
IUUC-Cja-019983	Callithrix jacchus	46.28	0.00e+00	1355.00
IUUC-Cfa-020903	Canis familiaris	47.45	0.00e+00	1412.00
IUUC-Cpo-021732	Cavia porcellus	45.34	0.00e+00	1328.00
IUUC-Csa-023083	Chlorocebus sabaeus	55.98	0.00e+00	1543.00
IUUC-Cho-024469	Choloepus hoffmanni	39.16	0.00e+00	692.00
IUUC-Dre-027995	Danio rerio	53.67	0.00e+00	4067.00
IUUC-Dor-030569	Dipodomys ordii	59.04	0.00e+00	972.00
IUUC-Eca-033945	Equus caballus	45.25	0.00e+00	1325.00
IUUC-Fca-035922	Felis catus	45.35	0.00e+00	1332.00
IUUC-Gmo-039403	Gadus morhua	69.54	0.00e+00	2804.00
IUUC-Gac-041896	Gasterosteus aculeatus	73.91	0.00e+00	4568.00
IUUC-Ggo-044812	Gorilla gorilla	46.38	0.00e+00	1265.00
IUUC-Hsa-046595	Homo sapiens	47.82	0.00e+00	1359.00
IUUC-Itr-048303	Ictidomys tridecemlineatus	46.21	0.00e+00	1374.00
IUUC-Lch-050086	Latimeria chalumnae	46.06	0.00e+00	1317.00
IUUC-Loc-052891	Lepisosteus oculatus	57.35	0.00e+00	4333.00
IUUC-Laf-054348	Loxodonta africana	43.53	0.00e+00	1154.00
IUUC-Mcc-054868	Macaca mulatta	47.07	0.00e+00	1351.00
IUUC-Mga-059541	Meleagris gallopavo	47.70	0.00e+00	1400.00
IUUC-Mmr-061092	Microcebus murinus	49.95	0.00e+00	2883.00
IUUC-Mdo-062610	Monodelphis domestica	63.81	0.00e+00	806.00
IUUC-Mmu-063666	Mus musculus	45.69	0.00e+00	1280.00
IUUC-Mpu-066366	Mustela putorius furo	46.53	0.00e+00	1353.00
IUUC-Mlu-068201	Myotis lucifugus	47.22	0.00e+00	1308.00
IUUC-Nle-069232	Nomascus leucogenys	49.38	0.00e+00	2801.00
IUUC-Ont-072401	Oreochromis niloticus	76.01	0.00e+00	3700.00
IUUC-Oan-072945	Ornithorhynchus anatinus	56.13	0.00e+00	1548.00
IUUC-Ocu-074920	Oryctolagus cuniculus	55.51	0.00e+00	1534.00
IUUC-Ola-086436	Oryzias latipes	73.02	0.00e+00	4627.00
IUUC-Oga-088637	Otolemur garnettii	46.75	0.00e+00	1336.00
IUUC-Oar-089363	Ovis aries	46.85	0.00e+00	1358.00
IUUC-Ptr-091527	Pan troglodytes	45.52	0.00e+00	1654.00
IUUC-Pan-092102	Papio anubis	46.11	0.00e+00	1303.00
IUUC-Pfo-096288	Poecilia formosa	97.25	0.00e+00	7619.00
IUUC-Pab-098241	Pongo abelii	60.88	0.00e+00	1123.00
IUUC-Pca-100103	Procavia capensis	63.25	0.00e+00	929.00
IUUC-Pva-102238	Pteropus vampyrus	57.02	0.00e+00	1022.00
IUUC-Sha-106550	Sarcophilus harrisii	46.55	0.00e+00	1351.00
IUUC-Sar-113183	Sorex araneus	67.38	1.00e-105	380.00
IUUC-Tgu-116677	Taeniopygia guttata	47.44	0.00e+00	1372.00
IUUC-Tru-118037	Takifugu rubripes	74.53	0.00e+00	2958.00
IUUC-Tsy-118932	Tarsius syrichta	61.24	0.00e+00	1169.00
IUUC-Tni-119970	Tetraodon nigroviridis	72.34	0.00e+00	3301.00
IUUC-Ttr-129051	Tursiops truncatus	45.80	0.00e+00	1293.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence