iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-035570

Ensembl Protein ID

ENSFCAP00000018080.1

UniProt Accession

M3WUP3; M3WUP3_FELCA

Genbank Protein ID

ENSFCAP00000018080

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02185612

Gene Name

UHRF2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000026987.1	ENSFCAT00000028702.1	ENSFCAP00000018080.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.20e-08	34.2	347	394
ULD/UDP/UBQ/UBQ_PIM	1.30e-17	63.6	1	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C++Cg ++e + + + C++C+ ++H  Cl+++  +++p++e+w+Cp+C+
   Q: 347  SCHICGGKQEPN-MQLLCDECNMAYHIYCLNPP-LDKVPEEEYWYCPSCK 394
           6*****999977.7889****************.***************8 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgke..fel.evseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           m+++v+t +g++    + +vs++ t+eel+e++++ ++v pe+q+L y Gk+L++  tL ++++  ++++ l+v++++
   Q: 1    MWIQVRTIDGSQtrT-IeDVSRKATIEELRERVWALFDVRPECQRLFYRGKQLENGYTLFDYDVGLNDIIQLLVRPDP 77
           89********99744.45********************************************************9876 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MWIQVRTIDG SQTRTIEDVS RKATIEELRE RVWALFDVRP ECQRLFYRGK QLENGYTLFD 60
YDVGLNDIIQ LLVRPDPDLP STSKQTDVQA KPCSNSPPKV KKTPRVGLSG QPSTSTCDFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGGATCC AGGTTCGCAC CATCGACGGC TCTCAGACGC GCACCATTGA GGACGTGTCT 60
CGCAAAGCCA CAATTGAGGA GCTGCGCGAA CGGGTGTGGG CGCTCTTCGA CGTGCGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR015947--PUA-like_domain
IPR014722--Rib_L2_dom2
IPR003105--SRA_YDG
IPR021991--TTD_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50053--UBIQUITIN_2
PS51015--YDG
PS50016--ZF_PHD_2

Pfam

PF00628--PHD
PF02182--SAD_SRA
PF12148--TTD
PF00240--ubiquitin

SMART

SM00249--PHD
SM00466--SRA
SM00213--UBQ

Gene Ontology

GO:0005720--C:nuclear heterochromatin
GO:0005654--C:nucleoplasm
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0030154--P:cell differentiation
GO:0008283--P:cell proliferation
GO:0010216--P:maintenance of DNA methylation
GO:0071158--P:positive regulation of cell cycle arrest
GO:0051865--P:protein autoubiquitination
GO:0016567--P:protein ubiquitination
GO:0090308--P:regulation of methylation-dependent chromatin silencing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000242	Aegilops tauschii	35.58	4.00e-43	169.00
IUUC-Aml-001401	Ailuropoda melanoleuca	98.54	0.00e+00	1481.00
IUUC-Aca-005287	Anolis carolinensis	68.52	0.00e+00	1082.00
IUUC-Aly-006276	Arabidopsis lyrata	34.58	1.00e-45	177.00
IUUC-Ath-007096	Arabidopsis thaliana	34.19	8.00e-44	171.00
IUUC-Ame-010777	Astyanax mexicanus	62.45	0.00e+00	857.00
IUUC-Bta-012710	Bos taurus	94.61	0.00e+00	1348.00
IUUC-Bdi-014586	Brachypodium distachyon	35.54	2.00e-44	174.00
IUUC-Bol-015235	Brassica oleracea	34.82	1.00e-43	171.00
IUUC-Bra-017592	Brassica rapa	35.54	5.00e-43	169.00
IUUC-Cja-019807	Callithrix jacchus	91.40	0.00e+00	1369.00
IUUC-Cfa-021096	Canis familiaris	98.54	0.00e+00	1455.00
IUUC-Cpo-022368	Cavia porcellus	92.19	0.00e+00	1400.00
IUUC-Csa-023951	Chlorocebus sabaeus	91.53	0.00e+00	1373.00
IUUC-Cho-024857	Choloepus hoffmanni	91.96	0.00e+00	991.00
IUUC-Dno-029950	Dasypus novemcinctus	92.33	0.00e+00	1367.00
IUUC-Ete-032375	Echinops telfairi	87.89	1.00e-148	520.00
IUUC-Eca-033272	Equus caballus	96.88	0.00e+00	1414.00
IUUC-Eeu-035077	Erinaceus europaeus	69.93	7.00e-122	430.00
IUUC-Fal-037082	Ficedula albicollis	69.08	0.00e+00	1068.00
IUUC-Gmo-038826	Gadus morhua	60.45	0.00e+00	878.00
IUUC-Gga-041062	Gallus gallus	68.78	0.00e+00	1077.00
IUUC-Gac-041859	Gasterosteus aculeatus	62.30	0.00e+00	942.00
IUUC-Gma-042831	Glycine max	35.21	8.00e-46	178.00
IUUC-Ggo-045639	Gorilla gorilla	91.27	0.00e+00	1378.00
IUUC-Hsa-046422	Homo sapiens	91.14	0.00e+00	1377.00
IUUC-Hvu-047471	Hordeum vulgare	36.50	2.00e-44	174.00
IUUC-Itr-048532	Ictidomys tridecemlineatus	93.28	0.00e+00	940.00
IUUC-Lch-050162	Latimeria chalumnae	52.33	0.00e+00	776.00
IUUC-Lpe-050756	Leersia perrieri	34.01	2.00e-42	167.00
IUUC-Loc-052318	Lepisosteus oculatus	63.26	0.00e+00	989.00
IUUC-Laf-053529	Loxodonta africana	93.25	0.00e+00	1413.00
IUUC-Mcc-055815	Macaca mulatta	91.53	0.00e+00	1376.00
IUUC-Meu-056189	Macropus eugenii	64.43	1.00e-145	510.00
IUUC-Mtr-057930	Medicago truncatula	33.05	6.00e-44	172.00
IUUC-Mmr-060646	Microcebus murinus	91.27	0.00e+00	1368.00
IUUC-Mdo-062659	Monodelphis domestica	69.91	0.00e+00	1092.00
IUUC-Mmu-064198	Mus musculus	90.33	0.00e+00	1391.00
IUUC-Mpu-065861	Mustela putorius furo	97.94	0.00e+00	794.00
IUUC-Mlu-067256	Myotis lucifugus	81.16	0.00e+00	1180.00
IUUC-Nle-069901	Nomascus leucogenys	91.06	0.00e+00	1273.00
IUUC-Opr-070219	Ochotona princeps	87.83	1.00e-135	476.00
IUUC-Ont-072019	Oreochromis niloticus	55.84	0.00e+00	913.00
IUUC-Oan-073109	Ornithorhynchus anatinus	76.76	0.00e+00	640.00
IUUC-Ocu-074748	Oryctolagus cuniculus	89.22	0.00e+00	1228.00
IUUC-Oba-075108	Oryza barthii	33.52	2.00e-42	167.00
IUUC-Obr-076572	Oryza brachyantha	33.81	9.00e-43	168.00
IUUC-Ogl-077177	Oryza glaberrima	33.24	2.00e-42	167.00
IUUC-Ogu-078298	Oryza glumaepatula	33.24	2.00e-42	167.00
IUUC-Oin-079911	Oryza indica	33.24	2.00e-42	167.00
IUUC-Oni-082620	Oryza nivara	33.24	2.00e-42	167.00
IUUC-Opu-083974	Oryza punctata	33.81	1.00e-42	167.00
IUUC-Oru-084976	Oryza rufipogon	33.24	2.00e-42	167.00
IUUC-Osa-085339	Oryza sativa	33.24	2.00e-42	167.00
IUUC-Ola-086706	Oryzias latipes	62.37	0.00e+00	913.00
IUUC-Oga-088218	Otolemur garnettii	92.06	0.00e+00	1393.00
IUUC-Oar-090189	Ovis aries	94.97	0.00e+00	1454.00
IUUC-Ptr-091290	Pan troglodytes	91.14	0.00e+00	1377.00
IUUC-Pan-092391	Papio anubis	87.86	0.00e+00	1303.00
IUUC-Psi-093033	Pelodiscus sinensis	69.21	0.00e+00	1025.00
IUUC-Pfo-097186	Poecilia formosa	59.03	0.00e+00	830.00
IUUC-Pab-098211	Pongo abelii	91.40	0.00e+00	1374.00
IUUC-Pop-099357	Populus trichocarpa	33.33	5.00e-45	175.00
IUUC-Pca-100531	Procavia capensis	86.69	0.00e+00	1212.00
IUUC-Pva-102266	Pteropus vampyrus	97.09	0.00e+00	1472.00
IUUC-Pyt-104740	Pyrenophora triticirepentis	28.85	4.00e-11	63.50
IUUC-Rno-105552	Rattus norvegicus	90.33	0.00e+00	1367.00
IUUC-Sha-106687	Sarcophilus harrisii	70.08	0.00e+00	999.00
IUUC-Sit-110588	Setaria italica	34.19	5.00e-42	166.00
IUUC-Sly-111415	Solanum lycopersicum	33.90	5.00e-44	172.00
IUUC-Stu-112842	Solanum tuberosum	32.31	2.00e-43	170.00
IUUC-Sar-113546	Sorex araneus	90.88	3.00e-141	495.00
IUUC-Sbi-114726	Sorghum bicolor	34.66	4.00e-42	166.00
IUUC-Tgu-116945	Taeniopygia guttata	68.23	0.00e+00	1009.00
IUUC-Tru-118292	Takifugu rubripes	61.81	0.00e+00	937.00
IUUC-Tsy-119249	Tarsius syrichta	90.21	0.00e+00	1263.00
IUUC-Tni-120750	Tetraodon nigroviridis	60.39	0.00e+00	896.00
IUUC-Tae-125473	Triticum aestivum	35.89	2.00e-43	170.00
IUUC-Tbe-127823	Tupaia belangeri	83.12	0.00e+00	886.00
IUUC-Ttr-128215	Tursiops truncatus	87.38	0.00e+00	1296.00
IUUC-Vpa-130073	Vicugna pacos	94.17	0.00e+00	1426.00
IUUC-Xtr-132771	Xenopus tropicalis	63.65	0.00e+00	988.00
IUUC-Xma-133888	Xiphophorus maculatus	63.47	0.00e+00	843.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence