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Tag Content
UUCD2 ID IUUC-Oan-073417
UUCD1 version UUC-OrA-00838
Ensembl Protein ID ENSOANP00000017660.2
UniProt Accession F7D679; F7D679_ORNAN
Protein Name Ubiquitinyl hydrolase 1
Gene Name USP3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOANG00000011148.2 ENSOANT00000017663.2 ENSOANP00000017660.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 3.10e-100 335.9 159 510
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalk 78
           tGl+NlgNtC+mN++LQ+Lsni+++ ++++e             +++ + +++ +++ +l+++++k + +lw+++++a+sp++l+ +++
   Q: 159  TGLRNLGNTCFMNAILQSLSNIQQFCCYFKElpavelrngktAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVW 247
           7******************************888888777765555555555688889******************************* PP
   S: 79   keaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           k+ ++f+gy+qqDa+Ef+++lld+l+ el+   n    +   +++s ls + ++   +  +++++ +F+g l++++ cl c+++s +++
   Q: 248  KIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSVILQENSGLSAS-NKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFD 335
           *****************************7755555555555555555554.688899999**************************** PP
   S: 168  pfldlslpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksre 247
           pfldlsl++p++  +k +         sl+dcL+sft  eel++ + y c kckkkq+++kk++++klP+vL+lhLkRf+++   + r+
   Q: 336  PFLDLSLDIPSQFRNKRSknqengpmcSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTA--YLRN 422
           **********66655444667899999****************************************************7755..799* PP
   S: 248  kinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlf 334
           k++++vefpl+ Ld++ ++ +pe++  e++ Y+L avvvH+G +++sGHY+ay+ + +g+W++f+Ds+Vt ++ee+v++   ++aY+lf
   Q: 423  KVDTYVEFPLRgLDMKCYLLEPENSGPESCLYDLAAVVVHHGsGVGSGHYTAYATH-EGRWFHFNDSTVTLTDEETVVK---AKAYILF 507
           ********************************************************.9*********************...******* PP
   S: 335  Ykr 337
           Y +
   Q: 508  YVE 510
           *76 PP
   
Organism Ornithorhynchus anatinus
Protein Sequence
(Fasta)
MECPHLGSSV CIAPDSAKFP HGSPSSWCCS VCRSNKSPWV CLTCSSVHCG RYVNGHAKKH 60
YEDAQIPLNN HKKTEKQEKV QHTVCMDCSS YSTYCLDCQF FKTNINKIFQ VLTIRSQLEG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oan-073417|DUB,USP|Ornithorhynchus anatinus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGCCGCCCTT CTTTTTTAAC GCGATGGGCG CGGGGGCGGC GCGCCGGCCG CTGGAGCGCT 60
GAGCGAGCGG GAGCGGGAGC GGGAGTCGCC CGCAGCAGCA GCAGCAGCAG CAGCAGCAGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oan-073417|DUB,USP|Ornithorhynchus anatinus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0070938--C:contractile ring
GO:0000790--C:nuclear chromatin
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair
GO:0016578--P:histone deubiquitination
GO:0000278--P:mitotic cell cycle
GO:0031647--P:regulation of protein stability
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001537 Ailuropoda melanoleuca 89.81 0.00e+00 877.00
IUUC-Apl-003358 Anas platyrhynchos 91.22 0.00e+00 840.00
IUUC-Aca-004454 Anolis carolinensis 87.30 0.00e+00 771.00
IUUC-Ame-011544 Astyanax mexicanus 72.92 0.00e+00 689.00
IUUC-Bta-012738 Bos taurus 90.21 0.00e+00 860.00
IUUC-Cel-018186 Caenorhabditis elegans 37.29 6.00e-56 211.00
IUUC-Cja-018893 Callithrix jacchus 89.81 0.00e+00 863.00
IUUC-Cfa-020607 Canis familiaris 90.38 0.00e+00 864.00
IUUC-Cpo-021828 Cavia porcellus 88.46 0.00e+00 844.00
IUUC-Csa-023884 Chlorocebus sabaeus 90.54 0.00e+00 701.00
IUUC-Cho-024863 Choloepus hoffmanni 80.38 0.00e+00 740.00
IUUC-Dre-028452 Danio rerio 69.66 0.00e+00 696.00
IUUC-Dno-029531 Dasypus novemcinctus 89.80 0.00e+00 801.00
IUUC-Dor-030913 Dipodomys ordii 81.74 2.00e-160 558.00
IUUC-Ete-032611 Echinops telfairi 84.62 0.00e+00 808.00
IUUC-Eca-033622 Equus caballus 90.20 0.00e+00 803.00
IUUC-Eeu-035268 Erinaceus europaeus 85.07 0.00e+00 729.00
IUUC-Fca-035801 Felis catus 90.00 0.00e+00 828.00
IUUC-Fal-036749 Ficedula albicollis 90.02 0.00e+00 800.00
IUUC-Gmo-039598 Gadus morhua 72.41 0.00e+00 719.00
IUUC-Gga-040883 Gallus gallus 91.43 0.00e+00 814.00
IUUC-Gac-042235 Gasterosteus aculeatus 71.59 0.00e+00 686.00
IUUC-Ggo-044767 Gorilla gorilla 84.52 0.00e+00 759.00
IUUC-Hsa-046581 Homo sapiens 90.38 0.00e+00 893.00
IUUC-Itr-047898 Ictidomys tridecemlineatus 90.38 0.00e+00 864.00
IUUC-Lch-049732 Latimeria chalumnae 85.77 0.00e+00 852.00
IUUC-Loc-052371 Lepisosteus oculatus 84.62 0.00e+00 840.00
IUUC-Laf-054565 Loxodonta africana 90.19 0.00e+00 864.00
IUUC-Mcc-055522 Macaca mulatta 90.38 0.00e+00 894.00
IUUC-Meu-056754 Macropus eugenii 81.69 3.00e-168 584.00
IUUC-Mga-060095 Meleagris gallopavo 87.24 5.00e-168 582.00
IUUC-Mmr-060839 Microcebus murinus 90.58 0.00e+00 865.00
IUUC-Mdo-062339 Monodelphis domestica 91.26 0.00e+00 701.00
IUUC-Mmu-063638 Mus musculus 89.04 0.00e+00 831.00
IUUC-Mpu-066647 Mustela putorius furo 90.11 0.00e+00 694.00
IUUC-Mlu-067921 Myotis lucifugus 88.57 0.00e+00 815.00
IUUC-Nle-069752 Nomascus leucogenys 90.77 0.00e+00 896.00
IUUC-Opr-070636 Ochotona princeps 75.96 0.00e+00 661.00
IUUC-Ont-071638 Oreochromis niloticus 72.84 0.00e+00 649.00
IUUC-Ocu-074620 Oryctolagus cuniculus 88.65 0.00e+00 850.00
IUUC-Ola-087281 Oryzias latipes 74.42 1.00e-166 578.00
IUUC-Olu-087697 Ostreococcus lucimarinus 40.72 6.00e-49 187.00
IUUC-Oga-088448 Otolemur garnettii 90.00 0.00e+00 885.00
IUUC-Oar-090132 Ovis aries 90.19 0.00e+00 863.00
IUUC-Ptr-090696 Pan troglodytes 90.02 0.00e+00 832.00
IUUC-Pan-092124 Papio anubis 90.00 0.00e+00 888.00
IUUC-Psi-093801 Pelodiscus sinensis 90.80 0.00e+00 699.00
IUUC-Pma-094300 Petromyzon marinus 70.79 8.00e-99 352.00
IUUC-Pfo-096330 Poecilia formosa 73.13 0.00e+00 718.00
IUUC-Pab-098191 Pongo abelii 90.58 0.00e+00 895.00
IUUC-Pca-100341 Procavia capensis 86.27 0.00e+00 650.00
IUUC-Pva-103177 Pteropus vampyrus 89.81 0.00e+00 851.00
IUUC-Rno-105048 Rattus norvegicus 87.74 0.00e+00 816.00
IUUC-Sha-107429 Sarcophilus harrisii 91.15 0.00e+00 816.00
IUUC-Sar-113024 Sorex araneus 88.06 0.00e+00 743.00
IUUC-Ssc-115749 Sus scrofa 83.63 3.00e-130 456.00
IUUC-Tgu-117277 Taeniopygia guttata 89.80 0.00e+00 825.00
IUUC-Tru-117844 Takifugu rubripes 73.51 0.00e+00 715.00
IUUC-Tsy-119456 Tarsius syrichta 87.32 0.00e+00 791.00
IUUC-Tni-120251 Tetraodon nigroviridis 70.31 0.00e+00 735.00
IUUC-Tbe-127423 Tupaia belangeri 83.85 0.00e+00 781.00
IUUC-Ttr-128401 Tursiops truncatus 83.84 0.00e+00 722.00
IUUC-Vpa-130549 Vicugna pacos 77.84 2.00e-143 501.00
IUUC-Xtr-131892 Xenopus tropicalis 77.88 0.00e+00 739.00
Created Date 25-Jun-2017

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