iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062804

UUCD1 version

UUC-MoD-01032

Ensembl Protein ID

ENSMODP00000004515.1

UniProt Accession

F7FAJ7; F7FAJ7_MONDO

Protein Name

Uncharacterized protein

Gene Name

UBE2R2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000003686.1	ENSMODT00000004614.1	ENSMODP00000004515.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.60e-49	166.7	13	153

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 2    lkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk... 87
           l+ elk+l+++p+eg+++++vdesdl++wev+i+Gp++t Yegg+Fk++i+fp dYP++PP+++fltk++hPn+yenG+vC+sil+   
   Q: 13   LMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNTLYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHppv 101
           678**********************************************************************************9999 PP
   S: 88   ........eeekWspalsvesvllsiqsllaepnpesplneeaaellkknre 131
                   ++e+W+p+++v+++lls++sll+epn+ sp+n++a+ +++k+r 
   Q: 102  ddpqsgelPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKWRD 153
           99999*9*************************************99998875 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAQQQMTSSQ KALMLELKSL QEEPVEGFRI TLVDESDLYN WEVAIFGPPN TLYEGGYFKA 60
HIKFPIDYPY SPPTFRFLTK MWHPNIYENG DVCISILHPP VDDPQSGELP SERWNPTQNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCGCCGCCGC CGCCGCCTCC GCCGCCGCCG CTGCCATGGC CCAGCAGCAG ATGACCAGCT 60
CGCAGAAAGC CCTGATGCTG GAGCTCAAAT CCCTACAGGA GGAGCCGGTG GAGGGCTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0006513--P:protein monoubiquitination

KEGG

mdo:100011407

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003563	Anas platyrhynchos	98.64	4.00e-85	306.00
IUUC-Aca-004589	Anolis carolinensis	97.54	6.00e-118	416.00
IUUC-Ate-010563	Aspergillus terreus	45.16	5.00e-37	147.00
IUUC-Ame-011300	Astyanax mexicanus	95.48	5.00e-114	403.00
IUUC-Bta-012968	Bos taurus	99.47	9.00e-112	395.00
IUUC-Cel-018460	Caenorhabditis elegans	66.84	3.00e-74	271.00
IUUC-Cja-018764	Callithrix jacchus	99.51	8.00e-120	422.00
IUUC-Cfa-020955	Canis familiaris	99.51	8.00e-120	422.00
IUUC-Cpo-021451	Cavia porcellus	99.51	8.00e-120	422.00
IUUC-Csa-024239	Chlorocebus sabaeus	99.51	8.00e-120	422.00
IUUC-Cho-024999	Choloepus hoffmanni	81.67	4.00e-26	111.00
IUUC-Cin-025344	Ciona intestinalis	70.20	3.00e-85	307.00
IUUC-Csv-025954	Ciona savignyi	71.94	2.00e-87	315.00
IUUC-Dre-028153	Danio rerio	94.09	2.00e-114	404.00
IUUC-Dno-029368	Dasypus novemcinctus	99.47	9.00e-112	395.00
IUUC-Dor-030686	Dipodomys ordii	99.51	8.00e-120	422.00
IUUC-Dme-032106	Drosophila melanogaster	74.61	5.00e-89	320.00
IUUC-Ete-033001	Echinops telfairi	99.13	6.00e-64	235.00
IUUC-Eca-034221	Equus caballus	98.63	4.00e-84	303.00
IUUC-Fca-036381	Felis catus	97.97	9.00e-85	305.00
IUUC-Fal-037135	Ficedula albicollis	99.51	5.00e-115	406.00
IUUC-Gmo-039565	Gadus morhua	93.43	2.00e-111	394.00
IUUC-Gga-040477	Gallus gallus	99.51	4.00e-115	407.00
IUUC-Gac-041909	Gasterosteus aculeatus	92.42	6.00e-111	392.00
IUUC-Ggo-045150	Gorilla gorilla	99.01	7.00e-119	419.00
IUUC-Hsa-046611	Homo sapiens	99.51	8.00e-120	422.00
IUUC-Itr-047984	Ictidomys tridecemlineatus	92.12	5.00e-106	376.00
IUUC-Lch-050173	Latimeria chalumnae	99.51	5.00e-120	422.00
IUUC-Loc-051916	Lepisosteus oculatus	97.01	4.00e-114	404.00
IUUC-Laf-053860	Loxodonta africana	99.51	8.00e-120	422.00
IUUC-Mcc-054820	Macaca mulatta	99.51	8.00e-120	422.00
IUUC-Meu-056681	Macropus eugenii	94.58	3.00e-113	400.00
IUUC-Mmr-060666	Microcebus murinus	99.51	8.00e-120	422.00
IUUC-Mmu-063472	Mus musculus	99.51	8.00e-120	422.00
IUUC-Mlu-067397	Myotis lucifugus	94.92	6.00e-110	389.00
IUUC-Nle-070152	Nomascus leucogenys	99.08	4.00e-63	232.00
IUUC-Ont-071627	Oreochromis niloticus	92.50	4.00e-112	397.00
IUUC-Ocu-074229	Oryctolagus cuniculus	99.48	3.00e-112	397.00
IUUC-Ola-086587	Oryzias latipes	91.92	5.00e-111	393.00
IUUC-Oga-089161	Otolemur garnettii	99.47	9.00e-112	395.00
IUUC-Oar-089383	Ovis aries	99.51	8.00e-120	422.00
IUUC-Ptr-091096	Pan troglodytes	99.51	8.00e-120	422.00
IUUC-Pan-092560	Papio anubis	99.47	9.00e-112	395.00
IUUC-Psi-093263	Pelodiscus sinensis	99.32	8.00e-85	305.00
IUUC-Pma-094368	Petromyzon marinus	87.50	2.00e-75	273.00
IUUC-Pfo-096974	Poecilia formosa	92.93	2.00e-111	395.00
IUUC-Pab-098344	Pongo abelii	99.51	8.00e-120	422.00
IUUC-Rno-105821	Rattus norvegicus	99.51	8.00e-120	422.00
IUUC-Sha-107364	Sarcophilus harrisii	100.00	2.00e-120	424.00
IUUC-Sar-112992	Sorex araneus	95.52	3.00e-109	387.00
IUUC-Tgu-117074	Taeniopygia guttata	99.51	5.00e-115	406.00
IUUC-Tru-118641	Takifugu rubripes	91.88	7.00e-110	389.00
IUUC-Tsy-118797	Tarsius syrichta	96.38	5.00e-77	279.00
IUUC-Tni-119817	Tetraodon nigroviridis	91.92	2.00e-110	391.00
IUUC-Tbe-128014	Tupaia belangeri	99.51	8.00e-120	422.00
IUUC-Ttr-129037	Tursiops truncatus	98.92	7.00e-107	379.00
IUUC-Vpa-130680	Vicugna pacos	99.31	3.00e-83	300.00
IUUC-Xtr-131819	Xenopus tropicalis	99.46	1.00e-108	385.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence