iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-117820

Ensembl Protein ID

ENSTRUP00000020873.1

UniProt Accession

H2T883; H2T883_TAKRU

Protein Name

Uncharacterized protein

Gene Name

mdm2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000008338.1	ENSTRUT00000020960.1	ENSTRUP00000020873.1
ENSTRUG00000008338.1	ENSTRUT00000020961.1	ENSTRUP00000020874.1
ENSTRUG00000008338.1	ENSTRUT00000020962.1	ENSTRUP00000020875.1
ENSTRUG00000008338.1	ENSTRUT00000020963.1	ENSTRUP00000020876.1
ENSTRUG00000008338.1	ENSTRUT00000020964.1	ENSTRUP00000020877.1
ENSTRUG00000008338.1	ENSTRUT00000020965.1	ENSTRUP00000020878.1
ENSTRUG00000008338.1	ENSTRUT00000020966.1	ENSTRUP00000020879.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	40.23	9.00e-71	265.00	IUUC-Hsa-046376

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

IVYSSQVCGQ ILFRTTDSII VSSRAASCLD LQVRPNVEFH RLLQDAGAIK DVFTMKEVMF 60
YLGQYIIQKQ LYDQKQQHIV HCSHDELGRV LGVDSFSVKE PRVLFAMIMK NLVAVKNPES 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGTGTATT CTTCCCAAGT TTGTGGGCAG ATTTTATTCA GAACTGTGAC TTTTAGACGC 60
TCGTTTGTTT GTGTTGGAAC AGTCAGGCAG CTGCTGCAGC TCTGGCTCGT GGAGGCCGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR015459--MDM2_E3_ligase
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002039	Ailuropoda melanoleuca	40.12	2.00e-79	290.00
IUUC-Apl-003193	Anas platyrhynchos	42.97	2.00e-90	325.00
IUUC-Aca-004305	Anolis carolinensis	43.40	1.00e-74	274.00
IUUC-Ame-010675	Astyanax mexicanus	59.20	8.00e-71	261.00
IUUC-Bta-013270	Bos taurus	40.79	2.00e-78	286.00
IUUC-Cja-019744	Callithrix jacchus	40.12	1.00e-80	293.00
IUUC-Cfa-020807	Canis familiaris	40.40	2.00e-72	266.00
IUUC-Cpo-022182	Cavia porcellus	39.77	5.00e-80	291.00
IUUC-Csa-023541	Chlorocebus sabaeus	42.09	9.00e-81	294.00
IUUC-Cho-024831	Choloepus hoffmanni	54.90	1.00e-23	103.00
IUUC-Cin-025448	Ciona intestinalis	29.02	4.00e-16	77.80
IUUC-Dre-028419	Danio rerio	50.30	3.00e-99	355.00
IUUC-Dno-028950	Dasypus novemcinctus	40.20	1.00e-78	287.00
IUUC-Dor-031048	Dipodomys ordii	42.23	3.00e-39	155.00
IUUC-Ete-032264	Echinops telfairi	41.48	2.00e-44	173.00
IUUC-Eca-033301	Equus caballus	41.78	2.00e-83	302.00
IUUC-Eeu-035005	Erinaceus europaeus	36.47	1.00e-62	234.00
IUUC-Fca-035454	Felis catus	39.69	2.00e-78	286.00
IUUC-Fal-036720	Ficedula albicollis	46.31	4.00e-40	158.00
IUUC-Gmo-039296	Gadus morhua	49.35	2.00e-56	212.00
IUUC-Gga-040251	Gallus gallus	44.97	4.00e-85	308.00
IUUC-Gac-041528	Gasterosteus aculeatus	63.99	2.00e-55	209.00
IUUC-Ggo-044948	Gorilla gorilla	41.72	8.00e-53	201.00
IUUC-Hsa-046376	Homo sapiens	42.19	2.00e-82	299.00
IUUC-Itr-048328	Ictidomys tridecemlineatus	41.30	4.00e-80	291.00
IUUC-Lch-050037	Latimeria chalumnae	46.55	8.00e-81	294.00
IUUC-Loc-051837	Lepisosteus oculatus	49.39	2.00e-107	382.00
IUUC-Laf-053483	Loxodonta africana	41.04	8.00e-83	300.00
IUUC-Mcc-055294	Macaca mulatta	42.19	2.00e-82	299.00
IUUC-Mga-060007	Meleagris gallopavo	45.06	2.00e-84	306.00
IUUC-Mmr-060673	Microcebus murinus	40.99	1.00e-82	300.00
IUUC-Mdo-063057	Monodelphis domestica	43.49	2.00e-90	326.00
IUUC-Mmu-063207	Mus musculus	41.15	2.00e-69	256.00
IUUC-Mpu-065836	Mustela putorius furo	40.39	2.00e-83	303.00
IUUC-Mlu-068193	Myotis lucifugus	39.29	1.00e-76	280.00
IUUC-Nle-069927	Nomascus leucogenys	41.60	5.00e-82	298.00
IUUC-Opr-070590	Ochotona princeps	38.82	2.00e-71	263.00
IUUC-Ont-071984	Oreochromis niloticus	67.02	2.00e-125	442.00
IUUC-Oan-072744	Ornithorhynchus anatinus	44.44	5.00e-84	304.00
IUUC-Ocu-074071	Oryctolagus cuniculus	40.38	6.00e-78	285.00
IUUC-Ola-087329	Oryzias latipes	65.58	1.00e-82	300.00
IUUC-Oga-088135	Otolemur garnettii	38.54	2.00e-72	266.00
IUUC-Oar-090078	Ovis aries	40.39	1.00e-79	290.00
IUUC-Ptr-091399	Pan troglodytes	41.60	5.00e-82	298.00
IUUC-Pan-092720	Papio anubis	42.19	2.00e-82	299.00
IUUC-Psi-093591	Pelodiscus sinensis	44.01	5.00e-57	215.00
IUUC-Pma-094500	Petromyzon marinus	67.86	2.00e-19	88.60
IUUC-Pfo-096316	Poecilia formosa	65.19	2.00e-125	442.00
IUUC-Pab-097696	Pongo abelii	41.68	2.00e-82	299.00
IUUC-Pca-100974	Procavia capensis	40.54	3.00e-82	298.00
IUUC-Pva-102488	Pteropus vampyrus	37.43	1.00e-60	227.00
IUUC-Rno-105641	Rattus norvegicus	41.47	1.00e-73	270.00
IUUC-Sha-107314	Sarcophilus harrisii	42.66	4.00e-90	325.00
IUUC-Sar-112938	Sorex araneus	38.37	4.00e-71	261.00
IUUC-Ssc-115495	Sus scrofa	40.28	6.00e-79	288.00
IUUC-Tgu-116623	Taeniopygia guttata	42.62	1.00e-85	310.00
IUUC-Tni-119793	Tetraodon nigroviridis	72.24	4.00e-78	285.00
IUUC-Tbe-127816	Tupaia belangeri	36.20	3.00e-46	179.00
IUUC-Ttr-129194	Tursiops truncatus	43.56	1.00e-51	197.00
IUUC-Vpa-130326	Vicugna pacos	37.55	5.00e-67	248.00
IUUC-Xtr-132216	Xenopus tropicalis	42.72	2.00e-85	310.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence