iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067536

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02007721

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000016977.2	ENSMLUT00000016982.2	ENSMLUP00000015480.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.00e-17	64.3	66	131
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-09	36.8	165	196

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+vLa   ++F+a+fl+e+ e k +  +ei+d + ++ ++l+kF+Y+++l++
   Q: 66   CDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAK-QTVIEIRDFDGDAIEDLVKFVYSSRLTL 131
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a+ +++ hF+
   Q: 165  PSNCLAVRAFAESHNRIDLMDMADQYACEHFT 196
           89*****************************7 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MASDSMNTKY PRNHFTKGKR QQHQQTKTRS SISDGDGDDS FIFEAQEAWK DFHGSLLRFY 60
ENGELCDVTL KVGSKLISCH KLVLACVIPY FRAMFLSEMA EAKQTVIEIR DFDGDAIEDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTTCAG ATTCTATGAA TACAAAATAC CCTAGGAATC ACTTCACTAA GGGGAAAAGG 60
CAGCAGCACC AGCAAACAAA GACTAGGTCT TCCATCAGTG ATGGCGATGG CGACGACTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	96.25	0.00e+00	1213.00
IUUC-Atr-002726	Amborella trichopoda	35.48	2.00e-42	167.00
IUUC-Apl-003978	Anas platyrhynchos	87.97	0.00e+00	1129.00
IUUC-Aca-004958	Anolis carolinensis	84.55	0.00e+00	1062.00
IUUC-Ame-011139	Astyanax mexicanus	80.94	0.00e+00	1047.00
IUUC-Bta-013142	Bos taurus	94.79	0.00e+00	1193.00
IUUC-Cel-018551	Caenorhabditis elegans	41.07	5.00e-130	458.00
IUUC-Cja-019650	Callithrix jacchus	95.77	0.00e+00	1229.00
IUUC-Cfa-021046	Canis familiaris	96.74	0.00e+00	1213.00
IUUC-Cpo-022445	Cavia porcellus	93.00	0.00e+00	1147.00
IUUC-Csa-023642	Chlorocebus sabaeus	96.91	0.00e+00	1243.00
IUUC-Cho-025012	Choloepus hoffmanni	78.50	0.00e+00	872.00
IUUC-Dre-027723	Danio rerio	81.96	0.00e+00	1048.00
IUUC-Dno-028964	Dasypus novemcinctus	94.14	0.00e+00	1006.00
IUUC-Dor-030899	Dipodomys ordii	82.15	1.00e-130	460.00
IUUC-Dse-031158	Dothistroma septosporum	31.08	1.00e-04	40.00
IUUC-Ete-032815	Echinops telfairi	91.69	0.00e+00	1183.00
IUUC-Eca-034162	Equus caballus	96.09	0.00e+00	1189.00
IUUC-Eeu-034660	Erinaceus europaeus	93.49	0.00e+00	1176.00
IUUC-Fca-035659	Felis catus	96.58	0.00e+00	1217.00
IUUC-Fal-037619	Ficedula albicollis	89.09	0.00e+00	1146.00
IUUC-Fox-037999	Fusarium oxysporum	32.47	2.00e-08	52.80
IUUC-Gmo-038546	Gadus morhua	84.11	0.00e+00	1031.00
IUUC-Ggr-040041	Gaeumannomyces graminis	31.29	2.00e-06	46.60
IUUC-Gga-040770	Gallus gallus	88.94	0.00e+00	1110.00
IUUC-Gac-042557	Gasterosteus aculeatus	79.97	0.00e+00	1024.00
IUUC-Ggo-044741	Gorilla gorilla	96.75	0.00e+00	1241.00
IUUC-Hsa-046025	Homo sapiens	96.59	0.00e+00	1239.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	97.24	0.00e+00	1084.00
IUUC-Loc-052834	Lepisosteus oculatus	86.04	0.00e+00	994.00
IUUC-Laf-054513	Loxodonta africana	95.28	0.00e+00	1202.00
IUUC-Mcc-054707	Macaca mulatta	96.75	0.00e+00	1239.00
IUUC-Meu-056779	Macropus eugenii	88.98	0.00e+00	1135.00
IUUC-Mtr-058180	Medicago truncatula	31.15	5.00e-35	142.00
IUUC-Mga-059676	Meleagris gallopavo	88.62	0.00e+00	1107.00
IUUC-Mmr-061359	Microcebus murinus	94.96	0.00e+00	1186.00
IUUC-Mdo-062527	Monodelphis domestica	88.03	0.00e+00	1133.00
IUUC-Mmu-063112	Mus musculus	91.35	0.00e+00	1183.00
IUUC-Mac-064682	Musa acuminata	35.50	3.00e-40	159.00
IUUC-Mpu-065800	Mustela putorius furo	95.77	0.00e+00	1207.00
IUUC-Nle-069397	Nomascus leucogenys	96.75	0.00e+00	1240.00
IUUC-Opr-070599	Ochotona princeps	94.13	0.00e+00	1011.00
IUUC-Ont-072580	Oreochromis niloticus	81.14	0.00e+00	1035.00
IUUC-Oan-073180	Ornithorhynchus anatinus	89.90	0.00e+00	1145.00
IUUC-Ocu-074026	Oryctolagus cuniculus	95.11	0.00e+00	1179.00
IUUC-Ola-086776	Oryzias latipes	80.00	0.00e+00	1002.00
IUUC-Oga-088651	Otolemur garnettii	95.78	0.00e+00	1195.00
IUUC-Oar-089567	Ovis aries	93.65	0.00e+00	1169.00
IUUC-Ptr-091564	Pan troglodytes	96.75	0.00e+00	1241.00
IUUC-Pan-092578	Papio anubis	96.91	0.00e+00	1243.00
IUUC-Psi-093635	Pelodiscus sinensis	87.58	0.00e+00	1087.00
IUUC-Pma-094660	Petromyzon marinus	61.70	0.00e+00	745.00
IUUC-Pfo-097507	Poecilia formosa	80.71	0.00e+00	974.00
IUUC-Pab-098025	Pongo abelii	96.75	0.00e+00	1241.00
IUUC-Pca-101046	Procavia capensis	86.11	2.00e-176	612.00
IUUC-Ppe-101154	Prunus persica	31.87	1.00e-37	151.00
IUUC-Pva-102359	Pteropus vampyrus	97.50	0.00e+00	897.00
IUUC-Rno-105750	Rattus norvegicus	92.21	0.00e+00	1165.00
IUUC-Sha-107513	Sarcophilus harrisii	90.24	0.00e+00	1165.00
IUUC-Sly-111482	Solanum lycopersicum	31.47	1.00e-40	160.00
IUUC-Stu-112032	Solanum tuberosum	32.67	6.00e-42	165.00
IUUC-Sar-113616	Sorex araneus	70.65	1.00e-117	416.00
IUUC-Ssc-116205	Sus scrofa	94.92	0.00e+00	1018.00
IUUC-Tgu-117435	Taeniopygia guttata	89.09	0.00e+00	1139.00
IUUC-Tru-118709	Takifugu rubripes	80.43	0.00e+00	1033.00
IUUC-Tsy-119466	Tarsius syrichta	97.97	0.00e+00	1085.00
IUUC-Tni-119988	Tetraodon nigroviridis	80.30	0.00e+00	1027.00
IUUC-Tbe-127704	Tupaia belangeri	95.95	0.00e+00	1044.00
IUUC-Ttr-128892	Tursiops truncatus	97.38	0.00e+00	907.00
IUUC-Vpa-130545	Vicugna pacos	95.50	0.00e+00	1026.00
IUUC-Xtr-132289	Xenopus tropicalis	82.96	0.00e+00	1022.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence