iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022436

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02012242

Gene Name

KLHL40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000015231.3	ENSCPOT00000015378.2	ENSCPOP00000016355.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	6.60e-15	55.2	34	97
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.60e-06	26.3	131	161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           D+++  g++ef++h++vLaa+S++F++ fl e e+    ++v +++v+p+v+ ++l++lYt+++ ++
   Q: 34   DCVVRAGEREFPCHRLVLAACSPYFRSRFLAEPES---AGEVRLEEVSPDVVAQVLHYLYTSEIALD 97
           99999************************998776...579*********************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
            Ncl+++r++ l+dc +L+ aa+dfi+  F+
   Q: 131  ANCLAVFRLGLLLDCARLAVAARDFICARFP 161
           6***************************995 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MALGLEQAEE QRLYQQTLLQ DGLKDMLDHG KFLDCVVRAG EREFPCHRLV LAACSPYFRS 60
RFLAEPESAG EVRLEEVSPD VVAQVLHYLY TSEIALDEAS VQDLFAAAHR FQIPSIFTIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCTGG GCTTGGAGCA GGCGGAGGAG CAGCGGCTGT ACCAGCAGAC GCTGCTGCAG 60
GACGGGCTCA AGGACATGCT GGACCACGGC AAGTTTCTGG ACTGTGTGGT GCGCGCGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030607--KLHL40
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031397--P:negative regulation of protein ubiquitination
GO:0048741--P:skeletal muscle fiber development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001792	Ailuropoda melanoleuca	83.65	0.00e+00	1045.00
IUUC-Apl-003748	Anas platyrhynchos	68.97	0.00e+00	893.00
IUUC-Aca-005275	Anolis carolinensis	62.38	0.00e+00	813.00
IUUC-Acl-008133	Aspergillus clavatus	32.26	7.00e-04	38.90
IUUC-Ame-011294	Astyanax mexicanus	54.91	0.00e+00	716.00
IUUC-Bta-012801	Bos taurus	87.98	0.00e+00	1131.00
IUUC-Cja-019795	Callithrix jacchus	88.85	0.00e+00	1010.00
IUUC-Cfa-021245	Canis familiaris	87.22	0.00e+00	786.00
IUUC-Csa-023105	Chlorocebus sabaeus	89.37	0.00e+00	1122.00
IUUC-Dre-028603	Danio rerio	58.63	0.00e+00	759.00
IUUC-Dno-030015	Dasypus novemcinctus	76.51	0.00e+00	645.00
IUUC-Dse-031465	Dothistroma septosporum	29.55	4.00e-05	42.40
IUUC-Eca-034393	Equus caballus	88.57	0.00e+00	1053.00
IUUC-Fca-035823	Felis catus	77.50	0.00e+00	966.00
IUUC-Fal-037632	Ficedula albicollis	70.05	0.00e+00	872.00
IUUC-Gmo-039697	Gadus morhua	56.87	0.00e+00	737.00
IUUC-Gga-040525	Gallus gallus	69.45	0.00e+00	895.00
IUUC-Gac-042421	Gasterosteus aculeatus	59.90	0.00e+00	773.00
IUUC-Ggo-045596	Gorilla gorilla	89.37	0.00e+00	1122.00
IUUC-Hsa-046235	Homo sapiens	89.05	0.00e+00	1119.00
IUUC-Itr-048612	Ictidomys tridecemlineatus	89.89	0.00e+00	1148.00
IUUC-Lch-050123	Latimeria chalumnae	65.50	0.00e+00	865.00
IUUC-Loc-051824	Lepisosteus oculatus	61.46	0.00e+00	810.00
IUUC-Laf-053485	Loxodonta africana	84.76	0.00e+00	720.00
IUUC-Mcc-054909	Macaca mulatta	89.05	0.00e+00	1120.00
IUUC-Meu-055972	Macropus eugenii	74.20	0.00e+00	965.00
IUUC-Mga-059451	Meleagris gallopavo	69.77	0.00e+00	901.00
IUUC-Mmr-060736	Microcebus murinus	89.98	0.00e+00	1145.00
IUUC-Mdo-062563	Monodelphis domestica	74.68	0.00e+00	747.00
IUUC-Mmu-063549	Mus musculus	89.37	0.00e+00	1138.00
IUUC-Mpu-066262	Mustela putorius furo	88.94	0.00e+00	1140.00
IUUC-Mlu-067210	Myotis lucifugus	88.44	0.00e+00	1131.00
IUUC-Nle-069300	Nomascus leucogenys	88.58	0.00e+00	785.00
IUUC-Opr-070384	Ochotona princeps	83.81	0.00e+00	1028.00
IUUC-Ont-071273	Oreochromis niloticus	58.48	0.00e+00	751.00
IUUC-Ocu-074499	Oryctolagus cuniculus	89.47	0.00e+00	1123.00
IUUC-Ola-087175	Oryzias latipes	58.83	0.00e+00	747.00
IUUC-Oga-088855	Otolemur garnettii	88.85	0.00e+00	1131.00
IUUC-Oar-089342	Ovis aries	75.16	0.00e+00	897.00
IUUC-Ptr-091028	Pan troglodytes	88.79	0.00e+00	782.00
IUUC-Pan-091827	Papio anubis	89.37	0.00e+00	1122.00
IUUC-Psi-092998	Pelodiscus sinensis	69.45	0.00e+00	901.00
IUUC-Pma-094586	Petromyzon marinus	61.60	9.00e-95	339.00
IUUC-Pfo-096216	Poecilia formosa	57.79	0.00e+00	761.00
IUUC-Pab-097656	Pongo abelii	87.86	0.00e+00	686.00
IUUC-Pva-102331	Pteropus vampyrus	80.29	0.00e+00	996.00
IUUC-Pyt-104655	Pyrenophora triticirepentis	33.82	9.00e-05	41.20
IUUC-Rno-105613	Rattus norvegicus	87.30	0.00e+00	1000.00
IUUC-Sha-107091	Sarcophilus harrisii	75.75	0.00e+00	1002.00
IUUC-Sar-112941	Sorex araneus	83.15	0.00e+00	770.00
IUUC-Ssc-116276	Sus scrofa	88.94	0.00e+00	1140.00
IUUC-Tgu-116494	Taeniopygia guttata	69.77	0.00e+00	905.00
IUUC-Tru-118614	Takifugu rubripes	59.38	0.00e+00	766.00
IUUC-Tsy-119499	Tarsius syrichta	86.58	0.00e+00	654.00
IUUC-Tni-119776	Tetraodon nigroviridis	59.45	0.00e+00	770.00
IUUC-Tbe-127806	Tupaia belangeri	81.51	0.00e+00	1029.00
IUUC-Ttr-128813	Tursiops truncatus	88.12	0.00e+00	1127.00
IUUC-Vpa-130127	Vicugna pacos	87.56	0.00e+00	678.00
IUUC-Xtr-132942	Xenopus tropicalis	65.70	0.00e+00	852.00
IUUC-Xma-133573	Xiphophorus maculatus	58.25	0.00e+00	734.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence