iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053798

Ensembl Protein ID

ENSLAFP00000000522.4

UniProt Accession

G3SM27; G3SM27_LOXAF

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000000620.4	ENSLAFT00000000620.4	ENSLAFP00000000522.4
ENSLAFG00000000620.4	ENSLAFT00000028750.1	ENSLAFP00000020837.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.70e-61	202.7	1098	1150

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy a+n+deL++ kG  + v+  ++ d +W++g  e +g  GlfP+n+v+ 
   Q: 1098 QVIAMYDYVANNEDELNFSKGQLINVL--NKDDPDWWQG--EISGVTGLFPSNYVKM 1150
           6899***********************..8889******..9*************85 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MMAQFPTTMN GGPNMWAITS EERTKHDKQF DNLKPSGGYI TGDQARTFFL QSGLPAPVLA 60
EIWALSDLNK DGKMDQQEFS IAMKLIKLKL QGQQLPVVLP PIMKQPPMFS PLISARFGMG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATGGCTC AGTTTCCCAC AACTATGAAT GGTAAGCAGC TTTGTGCTTG TCACTAGATA 60
AAGAGATTAT GGGGATTTTT TTGTAGAGGT TATAAAATAC TTACATATTT TTCCTTAAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50002--SH3

Pfam

PF12763--EF-hand_4
PF00621--RhoGEF
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00054--EFh
SM00027--EH
SM00326--SH3

Gene Ontology

GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001455	Ailuropoda melanoleuca	87.25	0.00e+00	1392.00
IUUC-Apl-004205	Anas platyrhynchos	76.87	0.00e+00	1774.00
IUUC-Bta-013248	Bos taurus	85.92	0.00e+00	1313.00
IUUC-Cel-018490	Caenorhabditis elegans	33.18	2.00e-55	211.00
IUUC-Cja-019259	Callithrix jacchus	81.21	0.00e+00	1090.00
IUUC-Cfa-020628	Canis familiaris	86.69	0.00e+00	1407.00
IUUC-Cpo-022427	Cavia porcellus	79.27	0.00e+00	1888.00
IUUC-Csa-023122	Chlorocebus sabaeus	85.36	0.00e+00	1381.00
IUUC-Cho-024840	Choloepus hoffmanni	80.77	0.00e+00	739.00
IUUC-Dno-029419	Dasypus novemcinctus	89.08	0.00e+00	1416.00
IUUC-Dme-032099	Drosophila melanogaster	28.65	5.00e-64	239.00
IUUC-Ete-033184	Echinops telfairi	76.66	1.00e-136	481.00
IUUC-Eca-034196	Equus caballus	87.14	0.00e+00	1353.00
IUUC-Eeu-034972	Erinaceus europaeus	76.32	2.00e-167	583.00
IUUC-Fca-035757	Felis catus	86.89	0.00e+00	1405.00
IUUC-Gmo-039079	Gadus morhua	54.92	0.00e+00	649.00
IUUC-Gac-041927	Gasterosteus aculeatus	48.07	0.00e+00	944.00
IUUC-Ggo-045405	Gorilla gorilla	86.11	0.00e+00	1910.00
IUUC-Hsa-046833	Homo sapiens	87.20	0.00e+00	1355.00
IUUC-Itr-048978	Ictidomys tridecemlineatus	84.46	0.00e+00	988.00
IUUC-Mcc-054709	Macaca mulatta	86.74	0.00e+00	1382.00
IUUC-Mmr-060891	Microcebus murinus	86.52	0.00e+00	1412.00
IUUC-Mmu-064226	Mus musculus	87.05	0.00e+00	1416.00
IUUC-Mpu-066431	Mustela putorius furo	85.33	0.00e+00	1390.00
IUUC-Nle-070116	Nomascus leucogenys	85.19	0.00e+00	1357.00
IUUC-Ptr-091667	Pan troglodytes	87.38	0.00e+00	1348.00
IUUC-Pan-091723	Papio anubis	88.03	0.00e+00	1392.00
IUUC-Pab-098755	Pongo abelii	87.31	0.00e+00	1359.00
IUUC-Pva-102433	Pteropus vampyrus	87.25	0.00e+00	1380.00
IUUC-Sha-107396	Sarcophilus harrisii	65.03	0.00e+00	729.00
IUUC-Sar-112978	Sorex araneus	84.59	0.00e+00	1367.00
IUUC-Ssc-115562	Sus scrofa	80.56	0.00e+00	1196.00
IUUC-Tsy-118961	Tarsius syrichta	83.52	0.00e+00	732.00
IUUC-Tbe-127477	Tupaia belangeri	87.70	0.00e+00	666.00
IUUC-Vpa-130035	Vicugna pacos	96.83	5.00e-168	585.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence