iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000026098.2	ENSXETT00000039466.3	ENSXETP00000039466.3
ENSXETG00000026098.2	ENSXETT00000060923.1	ENSXETP00000058508.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	4.50e-61	202.9	1154	1206

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+++ydy a+n+deL + kG  + v+  ++ d +W++g  e +g  GlfP+n+v+ 
   Q: 1154 QVIAMYDYIANNEDELHFGKGQLINVL--NKDDVDWWQG--EINGVTGLFPSNYVKM 1206
           6899***********************..78899*****..9*************85 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

LCLYAVFAGG PSMWAITTEE RAKHDKQFAS LKPINGLISG DQARSFFIQS GLPSSVLAEI 60
WALSDLNKDG KMDQLEFSIA MKLIKLKLQG QSLPLVLPPV MKQPPVFSPL TSSRYGRLEG 120

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Nucleotide Sequence
(Fasta)

ATGCTGCGGA ACACGATTTC TCACTTTCCC ACGGCCATGA ATGGTAAGTA CCGTTTGTAT 60
GCTCCCCCCC AGGAGAAGAA TGCAGAGTTC CAAGTATTGC ACTGTGTGGC ATTTGTTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR027029--Intersectin-2
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50002--SH3

Pfam

PF12763--EF-hand_4
PF00018--SH3_1
PF07653--SH3_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00054--EFh
SM00027--EH
SM00326--SH3

Gene Ontology

GO:0005509--F:calcium ion binding
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0006897--P:endocytosis
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008379	Aspergillus clavatus	45.83	2.00e-10	62.00
IUUC-Cne-027039	Cryptococcus neoformans	44.05	4.00e-15	77.80
IUUC-Kpa-049215	Komagataella pastoris	37.59	2.00e-14	73.90
IUUC-Laf-053798	Loxodonta africana	59.20	0.00e+00	855.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence