iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cne-026847

Ensembl Protein ID

AAW43634

UniProt Accession

P0CS26; Q55S12; Q5KGG4; VPS27_CRYNJ

Genbank Protein ID

AAW43634.1

Protein Name

Vacuolar protein sorting-associated protein 27

Genbank Nucleotide ID

AE017345

Gene Name

VPS27; CNE03710

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CNE03710	AAW43634	AAW43634

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UIM	31.56	1.00e-36	151.00	IUUC-Bta-012506
UBD/Alpha-Helix/UIM	38.91	2.00e-39	161.00	IUUC-Dme-031952
UBD/Alpha-Helix/DUIM	31.89	6.00e-37	153.00	IUUC-Hsa-046009
UBD/Alpha-Helix/VHS	31.89	6.00e-37	153.00	IUUC-Hsa-046009
UBD/Alpha-Helix/UIM	35.09	7.00e-37	153.00	IUUC-Mmu-063952
UBD/Alpha-Helix/VHS	32.11	5.00e-37	153.00	IUUC-Rno-105125
UBD/Alpha-Helix/UIM	32.20	1.00e-54	209.00	IUUC-Sce-106192
UBD/Alpha-Helix/UIM	35.68	3.00e-65	244.00	IUUC-Spo-108220

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cryptococcus neoformans

Functional Description
(View)

Component of the ESCRT-0 complex which is the sorting receptor for ubiquitinated cargo proteins at the multivesicular body (MVB) and recruits ESCRT-I to the MVB outer membrane.

Protein Sequence
(Fasta)

MSWLWGSTTN PQFEELAEKA CSPLNLPYPQ SEDIATALEV ADMIRSKAIQ PKMAMQSLKK 60
RIASKNGRVQ MYAIGLTDTC IKNGGDHFLL EVASKEFVDE LSNLIKATTT SPEVKQMLIK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCGTCTGC TGCCAGCCTC TTGCTTCCAT ACGGCACTCC ACCCCGCCCA TATCCGCTGT 60
CTCCATTGCC CGCCACCGCC CTTCTCCTAG TCCCAACAAT TTGCTTCCGC GCCGAGAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0967--Endosome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF02809--UIM
PF00790--VHS

SMART

SM00064--FYVE
SM00726--UIM
SM00288--VHS

Gene Ontology

GO:0010008--C:endosome membrane
GO:0046872--F:metal ion binding
GO:0006886--P:intracellular protein transport

KEGG

cne:CNE03710

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	34.22	7.00e-37	147.00
IUUC-Atr-002790	Amborella trichopoda	49.12	3.00e-11	62.80
IUUC-Apl-003662	Anas platyrhynchos	33.85	2.00e-32	132.00
IUUC-Aca-004940	Anolis carolinensis	35.65	2.00e-38	152.00
IUUC-Ago-007931	Ashbya gossypii	33.25	8.00e-50	189.00
IUUC-Acl-008274	Aspergillus clavatus	36.56	2.00e-76	278.00
IUUC-Afl-008521	Aspergillus flavus	39.43	2.00e-81	294.00
IUUC-Afu-008774	Aspergillus fumigatus	37.33	6.00e-77	280.00
IUUC-Ani-009445	Aspergillus nidulans	37.02	2.00e-78	285.00
IUUC-Ang-009863	Aspergillus niger	37.28	7.00e-76	276.00
IUUC-Ate-010444	Aspergillus terreus	38.57	3.00e-76	277.00
IUUC-Ame-011111	Astyanax mexicanus	34.32	1.00e-39	156.00
IUUC-Bgr-012087	Blumeria graminis	36.28	1.00e-71	262.00
IUUC-Bta-012506	Bos taurus	35.09	1.00e-38	152.00
IUUC-Bci-013782	Botrytis cinerea	36.81	8.00e-74	269.00
IUUC-Cel-018493	Caenorhabditis elegans	35.81	2.00e-37	149.00
IUUC-Cja-019998	Callithrix jacchus	34.06	3.00e-35	141.00
IUUC-Cfa-020615	Canis familiaris	34.68	3.00e-38	151.00
IUUC-Cpo-022019	Cavia porcellus	35.06	5.00e-39	154.00
IUUC-Cre-022770	Chlamydomonas reinhardtii	44.62	8.00e-09	53.90
IUUC-Csa-023596	Chlorocebus sabaeus	35.53	6.00e-39	154.00
IUUC-Cin-025488	Ciona intestinalis	34.84	4.00e-40	157.00
IUUC-Csv-025802	Ciona savignyi	30.84	5.00e-32	130.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	38.70	3.00e-80	291.00
IUUC-Dre-028353	Danio rerio	35.44	3.00e-39	154.00
IUUC-Dno-029005	Dasypus novemcinctus	35.65	9.00e-40	156.00
IUUC-Dor-030280	Dipodomys ordii	34.65	4.00e-38	151.00
IUUC-Dse-031238	Dothistroma septosporum	37.93	5.00e-74	270.00
IUUC-Dme-031952	Drosophila melanogaster	38.91	2.00e-40	159.00
IUUC-Ete-032235	Echinops telfairi	35.19	2.00e-37	148.00
IUUC-Eca-033873	Equus caballus	34.51	3.00e-37	148.00
IUUC-Eeu-034652	Erinaceus europaeus	32.40	1.00e-22	100.00
IUUC-Fca-036563	Felis catus	34.73	3.00e-39	155.00
IUUC-Fal-036649	Ficedula albicollis	34.95	2.00e-34	138.00
IUUC-Fox-037962	Fusarium oxysporum	35.76	4.00e-70	257.00
IUUC-Fso-038396	Fusarium solani	38.84	4.00e-76	277.00
IUUC-Gmo-039510	Gadus morhua	35.62	2.00e-40	159.00
IUUC-Ggr-039938	Gaeumannomyces graminis	37.18	2.00e-76	278.00
IUUC-Gga-040201	Gallus gallus	35.19	2.00e-38	152.00
IUUC-Gac-041459	Gasterosteus aculeatus	36.48	3.00e-40	158.00
IUUC-Ggo-044573	Gorilla gorilla	35.53	3.00e-39	155.00
IUUC-Hsa-046009	Homo sapiens	35.53	2.00e-39	155.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	34.68	8.00e-39	153.00
IUUC-Kpa-049327	Komagataella pastoris	32.48	3.00e-54	204.00
IUUC-Lch-050236	Latimeria chalumnae	30.41	2.00e-23	100.00
IUUC-Loc-051850	Lepisosteus oculatus	35.65	6.00e-36	144.00
IUUC-Lma-053252	Leptosphaeria maculans	36.63	4.00e-71	261.00
IUUC-Laf-053346	Loxodonta africana	35.68	7.00e-39	153.00
IUUC-Mcc-055789	Macaca mulatta	35.53	5.00e-39	154.00
IUUC-Meu-056329	Macropus eugenii	30.30	6.00e-28	117.00
IUUC-Mor-057205	Magnaporthe oryzae	36.36	5.00e-78	283.00
IUUC-Mpo-057295	Magnaporthe poae	36.85	5.00e-78	283.00
IUUC-Mla-058849	Melampsora laricipopulina	36.75	1.00e-56	213.00
IUUC-Mga-059361	Meleagris gallopavo	34.69	2.00e-36	145.00
IUUC-Mvi-060561	Microbotryum violaceum	36.38	4.00e-72	264.00
IUUC-Mmr-061122	Microcebus murinus	35.09	2.00e-38	151.00
IUUC-Mdo-062171	Monodelphis domestica	36.11	1.00e-38	153.00
IUUC-Mmu-063952	Mus musculus	35.09	6.00e-39	154.00
IUUC-Mpu-065852	Mustela putorius furo	35.09	2.00e-38	152.00
IUUC-Mlu-067475	Myotis lucifugus	38.10	8.00e-17	79.30
IUUC-Nfi-068539	Neosartorya fischeri	37.78	1.00e-77	282.00
IUUC-Ncr-068726	Neurospora crassa	37.80	4.00e-80	290.00
IUUC-Nle-070148	Nomascus leucogenys	32.02	7.00e-30	124.00
IUUC-Opr-070833	Ochotona princeps	35.94	6.00e-21	94.00
IUUC-Ont-071261	Oreochromis niloticus	36.11	7.00e-36	144.00
IUUC-Ocu-073922	Oryctolagus cuniculus	38.10	2.00e-16	78.60
IUUC-Opu-083654	Oryza punctata	47.22	1.00e-04	38.50
IUUC-Ola-087570	Oryzias latipes	33.19	4.00e-32	131.00
IUUC-Oga-089087	Otolemur garnettii	35.59	4.00e-33	134.00
IUUC-Oar-089534	Ovis aries	35.09	2.00e-38	152.00
IUUC-Ptr-091654	Pan troglodytes	32.89	1.00e-31	129.00
IUUC-Pan-092652	Papio anubis	35.53	3.00e-39	154.00
IUUC-Psi-093744	Pelodiscus sinensis	36.51	1.00e-17	82.80
IUUC-Pma-094312	Petromyzon marinus	34.56	4.00e-16	77.00
IUUC-Pno-095125	Phaeosphaeria nodorum	45.83	6.00e-68	249.00
IUUC-Pfo-096757	Poecilia formosa	36.68	5.00e-37	147.00
IUUC-Pab-097788	Pongo abelii	35.53	4.00e-39	154.00
IUUC-Pca-100145	Procavia capensis	31.14	4.00e-27	114.00
IUUC-Pva-102965	Pteropus vampyrus	35.06	6.00e-40	157.00
IUUC-Pgr-103609	Puccinia graminis	34.26	4.00e-60	223.00
IUUC-Ptt-103940	Puccinia triticina	37.82	1.00e-56	212.00
IUUC-Pte-104095	Pyrenophora teres	37.42	2.00e-74	271.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	37.42	2.00e-74	271.00
IUUC-Rno-105125	Rattus norvegicus	35.09	1.00e-38	153.00
IUUC-Sce-106192	Saccharomyces cerevisiae	32.45	3.00e-55	207.00
IUUC-Sha-107066	Sarcophilus harrisii	36.11	2.00e-38	152.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	41.74	1.00e-57	215.00
IUUC-Spo-108220	Schizosaccharomyces pombe	35.68	2.00e-66	244.00
IUUC-Ssl-108413	Sclerotinia sclerotiorum	41.46	7.00e-31	124.00
IUUC-Stu-112464	Solanum tuberosum	47.37	7.00e-12	64.70
IUUC-Sar-113393	Sorex araneus	30.60	5.00e-24	103.00
IUUC-Sre-114986	Sporisorium reilianum	48.52	7.00e-61	226.00
IUUC-Ssc-115258	Sus scrofa	50.00	1.00e-14	73.60
IUUC-Tgu-117505	Taeniopygia guttata	34.60	3.00e-36	144.00
IUUC-Tru-118494	Takifugu rubripes	34.93	2.00e-38	152.00
IUUC-Tni-120174	Tetraodon nigroviridis	36.09	2.00e-40	159.00
IUUC-Tca-121260	Theobroma cacao	29.75	2.00e-14	72.00
IUUC-Tre-122191	Trichoderma reesei	37.69	5.00e-76	276.00
IUUC-Tvi-122318	Trichoderma virens	37.34	2.00e-78	285.00
IUUC-Tme-126914	Tuber melanosporum	36.95	4.00e-77	280.00
IUUC-Tbe-127233	Tupaia belangeri	32.35	2.00e-12	65.50
IUUC-Ttr-129095	Tursiops truncatus	35.09	1.00e-38	153.00
IUUC-Uma-129475	Ustilago maydis	37.25	1.00e-74	272.00
IUUC-Vda-129908	Verticillium dahliae	44.29	6.00e-60	223.00
IUUC-Xtr-131900	Xenopus tropicalis	35.50	7.00e-40	157.00
IUUC-Xma-133124	Xiphophorus maculatus	37.12	8.00e-38	150.00
IUUC-Yli-134682	Yarrowia lipolytica	36.55	2.00e-68	251.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence