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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063483
UUCD1 version UUC-MuM-00402
Ensembl Protein ID ENSMUSP00000071245.6
UniProt Accession Q3UK78; B2RTD3; B7ZP23; Q9D3E5; Q9DCW8; PCGF5_MOUSE
Genbank Protein ID BAB22061.1; BAB31023.1; BAE26924.1; AAI39259.1; AAI39260.1; AAI45591.1
Protein Name Polycomb group RING finger protein 5; RING finger protein 159
Genbank Nucleotide ID AK002387; AK017984; AK146133; BC139258; BC139259; BC145590
Gene Name Pcgf5; Rnf159
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000024805.15 ENSMUST00000071267.12 ENSMUSP00000071245.6
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
miRNAMapRAID2
Protein-protein Interaction
IIDPINAHINT
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTM
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
ULD/UDP/UFD/RAWUL 1.30e-32 113.3 139 230
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   ULD/UDP/UFD/RAWUL
   S: 1    islsLeplesnkakddsk...lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwk....kegpLv 82
           i+++L++l++n++++d++   l+kk++rcs+r+tV+++kkfl++klkl+ssye+d+lc++e++++++t+e+i y+++w+    +++p+v
   Q: 139  IAICLDCLRNNGQSGDNVvkgLMKKFIRCSTRVTVGTIKKFLSLKLKLPSSYELDVLCNGEIMGKDHTMEFI-YMTRWRlrgeNSYPMV 226
           79**********************************************************************.*********9****** PP
   S: 83   LqYr 86
           LqYr
   Q: 227  LQYR 230
           ***9 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).
 Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).
Protein Sequence
(Fasta)
MATQRKHLVK DFNPYITCYI CKGYLIKPTT VTECLHTFCK TCIVQHFEDS NDCPRCGNQV 60
HETNPLEMLR LDNTLEEIIF KLVPGLREQE LQRELEFWKK NKPQENGQDD ISKVDKSKAD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063483|ULD,RAWUL|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTCGGGGCTT CTGGACATGG GGACCAGGAT GCCCCAGACT ATGTCCCATC CCATCGTGCA 60
TCTCACTAGT ACTGTGACCT TGAACAAAAA AACGTGAGTT CAGTTTCTTC TGCAAACTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063483|ULD,RAWUL|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF16207--RAWUL
SMART

SM00184--RING
Gene Ontology

GO:0005813--C:centrosome
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0031519--C:PcG protein complex
GO:0008270--F:zinc ion binding
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated
KEGG mmu:76073
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002093 Ailuropoda melanoleuca 89.19 2.00e-123 434.00
IUUC-Apl-003757 Anas platyrhynchos 87.89 3.00e-115 407.00
IUUC-Aca-005032 Anolis carolinensis 82.03 8.00e-106 376.00
IUUC-Ame-011418 Astyanax mexicanus 74.90 2.00e-99 354.00
IUUC-Bta-013081 Bos taurus 89.84 2.00e-123 434.00
IUUC-Cja-019296 Callithrix jacchus 88.67 7.00e-121 426.00
IUUC-Cfa-020437 Canis familiaris 89.45 1.00e-123 435.00
IUUC-Cpo-022107 Cavia porcellus 89.92 3.00e-124 437.00
IUUC-Csa-023103 Chlorocebus sabaeus 89.45 2.00e-116 411.00
IUUC-Cho-025053 Choloepus hoffmanni 54.69 2.00e-58 219.00
IUUC-Dre-028409 Danio rerio 77.97 2.00e-103 368.00
IUUC-Dno-030077 Dasypus novemcinctus 90.23 6.00e-125 439.00
IUUC-Dor-030893 Dipodomys ordii 88.53 5.00e-101 360.00
IUUC-Ete-033131 Echinops telfairi 71.88 1.00e-90 325.00
IUUC-Eca-034226 Equus caballus 86.72 2.00e-119 421.00
IUUC-Eeu-034466 Erinaceus europaeus 73.44 3.00e-93 334.00
IUUC-Fca-035545 Felis catus 90.23 4.00e-125 440.00
IUUC-Fal-037615 Ficedula albicollis 87.89 3.00e-115 407.00
IUUC-Gmo-038871 Gadus morhua 68.65 3.00e-81 294.00
IUUC-Gga-040926 Gallus gallus 87.11 2.00e-114 405.00
IUUC-Gac-042006 Gasterosteus aculeatus 75.00 3.00e-96 344.00
IUUC-Ggo-045087 Gorilla gorilla 89.45 2.00e-116 411.00
IUUC-Hsa-046738 Homo sapiens 89.45 2.00e-116 411.00
IUUC-Itr-048443 Ictidomys tridecemlineatus 87.30 1.00e-82 298.00
IUUC-Lch-050434 Latimeria chalumnae 81.64 7.00e-109 386.00
IUUC-Loc-052649 Lepisosteus oculatus 77.82 3.00e-108 384.00
IUUC-Laf-053509 Loxodonta africana 90.23 5.00e-125 439.00
IUUC-Mcc-055709 Macaca mulatta 89.45 2.00e-116 411.00
IUUC-Meu-056663 Macropus eugenii 72.66 9.00e-93 332.00
IUUC-Mga-059573 Meleagris gallopavo 87.01 4.00e-113 400.00
IUUC-Mmr-060776 Microcebus murinus 89.45 1.00e-122 432.00
IUUC-Mdo-061959 Monodelphis domestica 88.67 7.00e-122 429.00
IUUC-Mpu-066861 Mustela putorius furo 90.23 4.00e-125 440.00
IUUC-Mlu-067880 Myotis lucifugus 90.23 5.00e-125 439.00
IUUC-Nle-069264 Nomascus leucogenys 89.45 2.00e-116 411.00
IUUC-Opr-070746 Ochotona princeps 64.45 7.00e-75 273.00
IUUC-Ont-071361 Oreochromis niloticus 74.13 4.00e-101 360.00
IUUC-Oan-073482 Ornithorhynchus anatinus 81.17 7.00e-95 339.00
IUUC-Ocu-073885 Oryctolagus cuniculus 90.23 6.00e-125 439.00
IUUC-Ola-086999 Oryzias latipes 73.33 2.00e-99 354.00
IUUC-Oga-088504 Otolemur garnettii 89.45 2.00e-124 438.00
IUUC-Oar-089963 Ovis aries 90.23 2.00e-125 441.00
IUUC-Ptr-090820 Pan troglodytes 88.67 1.00e-115 408.00
IUUC-Pan-092600 Papio anubis 89.45 2.00e-116 411.00
IUUC-Psi-093699 Pelodiscus sinensis 87.89 1.00e-122 432.00
IUUC-Pma-094238 Petromyzon marinus 62.60 1.00e-85 309.00
IUUC-Pfo-096402 Poecilia formosa 78.57 3.00e-100 357.00
IUUC-Pab-097621 Pongo abelii 89.45 2.00e-116 411.00
IUUC-Pca-100342 Procavia capensis 89.06 5.00e-116 410.00
IUUC-Pva-103118 Pteropus vampyrus 90.23 5.00e-119 420.00
IUUC-Rno-105427 Rattus norvegicus 98.64 1.00e-113 402.00
IUUC-Sha-107627 Sarcophilus harrisii 84.13 2.00e-78 284.00
IUUC-Sar-113005 Sorex araneus 76.95 2.00e-110 391.00
IUUC-Ssc-116448 Sus scrofa 79.25 2.00e-81 295.00
IUUC-Tgu-117081 Taeniopygia guttata 87.89 3.00e-115 407.00
IUUC-Tru-117696 Takifugu rubripes 68.80 1.00e-92 332.00
IUUC-Tsy-119052 Tarsius syrichta 73.39 2.00e-86 311.00
IUUC-Tni-120530 Tetraodon nigroviridis 73.23 1.00e-92 332.00
IUUC-Tbe-127914 Tupaia belangeri 71.88 6.00e-91 327.00
IUUC-Ttr-128739 Tursiops truncatus 75.39 7.00e-96 343.00
IUUC-Vpa-130189 Vicugna pacos 89.45 3.00e-122 430.00
IUUC-Xtr-131995 Xenopus tropicalis 85.07 2.00e-99 354.00
IUUC-Xma-133038 Xiphophorus maculatus 74.48 9.00e-91 326.00
Created Date 25-Jun-2017

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