iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036589

Ensembl Protein ID

ENSFCAP00000005399.3

UniProt Accession

M3W4R5; M3W4R5_FELCA

Genbank Protein ID

ENSFCAP00000005399

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02132901

Gene Name

SOCS7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000005815.3	ENSFCAT00000005816.3	ENSFCAP00000005399.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.10e-14	54.0	391	438

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
           +++ +++s++ SLqhLCR++Ir++++++++   + LPLPk L++Y++++ y
   Q: 391  LYPVSRFSNVKSLQHLCRFRIRQLVRIDHI---PDLPLPKPLISYIRKFYY 438
           567899*********************998...*************99976 PP

Organism

Felis catus

Protein Sequence
(Fasta)

XDALLVLEGL ESEAESLETN SCSEEELSSP GRGGGGGGRL LLQPPGPELP PVPFPMQDLV 60
PPGRFSRGEQ QQPPPPPPPP GPLRPLAGPS RKGSLKIRLS RLFRTKSCNG GSGGGDGAGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNGC GACGCGCTGC TGGTCTTGGA GGGCTTGGAG TCGGAGGCCG 60
AGAGCCTGGA GACGAACAGC TGCTCGGAAG AGGAGCTCAG CAGCCCGGGC CGCGGAGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028423--SOCS7
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0045444--P:fat cell differentiation
GO:0008286--P:insulin receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0021819--P:layer formation in cerebral cortex
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0016567--P:protein ubiquitination
GO:0021942--P:radial glia guided migration of Purkinje cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001668	Ailuropoda melanoleuca	91.74	0.00e+00	654.00
IUUC-Apl-003277	Anas platyrhynchos	91.78	7.00e-73	265.00
IUUC-Aca-004639	Anolis carolinensis	97.83	1.00e-108	384.00
IUUC-Ame-011301	Astyanax mexicanus	69.74	2.00e-131	462.00
IUUC-Bta-013483	Bos taurus	97.33	0.00e+00	675.00
IUUC-Cja-019765	Callithrix jacchus	99.69	1.00e-163	568.00
IUUC-Cfa-020109	Canis familiaris	98.31	0.00e+00	655.00
IUUC-Cpo-021555	Cavia porcellus	95.07	5.00e-179	620.00
IUUC-Csa-023580	Chlorocebus sabaeus	95.89	0.00e+00	655.00
IUUC-Cho-024431	Choloepus hoffmanni	98.43	1.00e-71	263.00
IUUC-Dre-028183	Danio rerio	71.97	3.00e-140	492.00
IUUC-Dno-028858	Dasypus novemcinctus	94.43	0.00e+00	659.00
IUUC-Dor-031071	Dipodomys ordii	79.25	3.00e-114	404.00
IUUC-Dme-031876	Drosophila melanogaster	43.65	3.00e-43	170.00
IUUC-Ete-032928	Echinops telfairi	71.47	6.00e-102	364.00
IUUC-Eca-033250	Equus caballus	93.92	1.00e-177	615.00
IUUC-Eeu-034946	Erinaceus europaeus	88.94	1.00e-52	200.00
IUUC-Fal-037316	Ficedula albicollis	93.07	2.00e-112	398.00
IUUC-Gmo-038552	Gadus morhua	91.26	1.00e-53	201.00
IUUC-Gga-041248	Gallus gallus	97.30	2.00e-108	384.00
IUUC-Gac-041469	Gasterosteus aculeatus	83.47	6.00e-57	212.00
IUUC-Ggo-045282	Gorilla gorilla	99.37	9.00e-163	565.00
IUUC-Hsa-045926	Homo sapiens	95.65	0.00e+00	654.00
IUUC-Itr-048411	Ictidomys tridecemlineatus	95.45	7.00e-146	510.00
IUUC-Lch-049768	Latimeria chalumnae	71.49	8.00e-152	530.00
IUUC-Loc-051949	Lepisosteus oculatus	75.06	1.00e-129	457.00
IUUC-Laf-053410	Loxodonta africana	98.14	0.00e+00	654.00
IUUC-Mcc-054605	Macaca mulatta	86.71	0.00e+00	632.00
IUUC-Meu-056773	Macropus eugenii	79.87	1.00e-106	379.00
IUUC-Mvi-060489	Microbotryum violaceum	24.37	7.60e+00	25.00
IUUC-Mmr-060927	Microcebus murinus	97.80	0.00e+00	659.00
IUUC-Mdo-061892	Monodelphis domestica	89.60	5.00e-176	610.00
IUUC-Mmu-064246	Mus musculus	96.59	0.00e+00	653.00
IUUC-Mpu-065995	Mustela putorius furo	98.55	0.00e+00	638.00
IUUC-Mlu-067526	Myotis lucifugus	96.37	0.00e+00	671.00
IUUC-Nle-069317	Nomascus leucogenys	97.92	9.00e-165	573.00
IUUC-Ont-072258	Oreochromis niloticus	65.97	5.00e-118	418.00
IUUC-Oan-073703	Ornithorhynchus anatinus	80.49	1.00e-36	143.00
IUUC-Ocu-074577	Oryctolagus cuniculus	91.17	0.00e+00	666.00
IUUC-Oga-088426	Otolemur garnettii	94.16	0.00e+00	649.00
IUUC-Oar-089407	Ovis aries	97.35	0.00e+00	661.00
IUUC-Ptr-091327	Pan troglodytes	98.67	0.00e+00	635.00
IUUC-Pan-092064	Papio anubis	98.93	0.00e+00	648.00
IUUC-Psi-093834	Pelodiscus sinensis	94.67	8.00e-155	539.00
IUUC-Pfo-097100	Poecilia formosa	63.50	3.00e-117	416.00
IUUC-Pab-097695	Pongo abelii	98.67	0.00e+00	630.00
IUUC-Pca-100569	Procavia capensis	90.67	5.00e-171	594.00
IUUC-Pva-102784	Pteropus vampyrus	94.90	0.00e+00	644.00
IUUC-Ptt-103775	Puccinia triticina	38.46	1.00e+00	28.90
IUUC-Rno-105485	Rattus norvegicus	96.67	0.00e+00	655.00
IUUC-Sha-106720	Sarcophilus harrisii	93.93	1.00e-173	602.00
IUUC-Sar-112975	Sorex araneus	84.28	4.00e-128	450.00
IUUC-Ssc-116369	Sus scrofa	95.69	0.00e+00	652.00
IUUC-Tgu-116867	Taeniopygia guttata	87.15	2.00e-125	441.00
IUUC-Tru-117562	Takifugu rubripes	78.85	4.00e-101	361.00
IUUC-Tsy-118999	Tarsius syrichta	93.40	3.00e-146	510.00
IUUC-Tni-120793	Tetraodon nigroviridis	68.88	1.00e-129	456.00
IUUC-Tbe-127671	Tupaia belangeri	98.61	3.00e-128	451.00
IUUC-Ttr-128491	Tursiops truncatus	85.19	6.00e-134	470.00
IUUC-Vpa-130104	Vicugna pacos	91.75	4.00e-178	617.00
IUUC-Xtr-132507	Xenopus tropicalis	80.58	9.00e-146	509.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence