iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098170

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01266579

Gene Name

SOCS1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000007099.1	ENSPPYT00000008360.1	ENSPPYP00000008028.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.60e-13	50.3	165	212

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
            ++l+++++r+Lq+LCR +I+ ++g+++l    ++PL+++L+dYL+++++q
   Q: 165  GAPLRQRRVRPLQELCRQRIVATVGRENL---ARIPLNPVLRDYLSSFPFQ 212
           6789*************************...***************9986 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MVAHNQVAAD NAVSTAAEPR RRPEPSSSSS SSPAAPARPR PCPAVPVPAL APGDTHFRTF 60
RSHADYRRIT RASALLDACG FYWGPLSVHG AHERLRAEPV GTFLVRDSRQ RNCFFALSVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTAGCAC ACAACCAGGT GGCAGCCGAC AATGCAGTCT CCACAGCAGC AGAGCCCCGA 60
CGGCGGCCAG AGCCTTCCTC CTCTTCCTCC TCCTCGCCTG CGGCCCCCGC GCGCCCGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028411--SOCS1
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0000932--C:P-body
GO:0019210--F:kinase inhibitor activity
GO:0071230--P:cellular response to amino acid stimulus
GO:0019221--P:cytokine-mediated signaling pathway
GO:0045444--P:fat cell differentiation
GO:0007259--P:JAK-STAT cascade
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0042512--P:negative regulation of tyrosine phosphorylation of Stat1 protein
GO:0042518--P:negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0016567--P:protein ubiquitination
GO:0010534--P:regulation of activation of JAK2 kinase activity
GO:0050707--P:regulation of cytokine secretion
GO:0060334--P:regulation of interferon-gamma-mediated signaling pathway

KEGG

pon:100445635

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001204	Ailuropoda melanoleuca	89.16	5.00e-80	289.00
IUUC-Apl-003313	Anas platyrhynchos	61.50	4.00e-74	270.00
IUUC-Aca-005109	Anolis carolinensis	68.35	7.00e-63	233.00
IUUC-Ame-011550	Astyanax mexicanus	50.00	7.00e-49	186.00
IUUC-Bta-013411	Bos taurus	85.65	6.00e-94	336.00
IUUC-Cja-019595	Callithrix jacchus	95.31	1.00e-96	345.00
IUUC-Cfa-020563	Canis familiaris	97.52	3.00e-90	323.00
IUUC-Cpo-021374	Cavia porcellus	93.55	3.00e-95	340.00
IUUC-Csa-023333	Chlorocebus sabaeus	98.12	1.00e-96	345.00
IUUC-Dre-028507	Danio rerio	46.79	2.00e-44	171.00
IUUC-Dno-029406	Dasypus novemcinctus	91.55	9.00e-94	335.00
IUUC-Ete-032399	Echinops telfairi	92.49	4.00e-93	333.00
IUUC-Eca-033519	Equus caballus	82.63	1.00e-89	322.00
IUUC-Fal-036726	Ficedula albicollis	61.50	7.00e-76	276.00
IUUC-Gmo-039667	Gadus morhua	50.44	7.00e-27	113.00
IUUC-Gga-040970	Gallus gallus	61.97	2.00e-74	271.00
IUUC-Gac-041838	Gasterosteus aculeatus	45.00	1.00e-35	142.00
IUUC-Ggo-045569	Gorilla gorilla	84.98	4.00e-96	343.00
IUUC-Hsa-046010	Homo sapiens	97.18	2.00e-94	338.00
IUUC-Itr-047995	Ictidomys tridecemlineatus	100.00	1.00e-92	332.00
IUUC-Lch-050219	Latimeria chalumnae	61.49	1.00e-62	231.00
IUUC-Loc-052494	Lepisosteus oculatus	57.86	6.00e-55	206.00
IUUC-Laf-054219	Loxodonta africana	96.32	5.00e-72	262.00
IUUC-Mcc-054830	Macaca mulatta	97.67	4.00e-95	340.00
IUUC-Meu-056565	Macropus eugenii	69.86	2.00e-80	291.00
IUUC-Mga-060153	Meleagris gallopavo	61.50	2.00e-71	261.00
IUUC-Mmr-061365	Microcebus murinus	89.95	4.00e-93	333.00
IUUC-Mdo-062824	Monodelphis domestica	71.03	5.00e-80	290.00
IUUC-Mmu-064120	Mus musculus	90.14	7.00e-92	329.00
IUUC-Mpu-066839	Mustela putorius furo	90.74	3.00e-95	340.00
IUUC-Mlu-067829	Myotis lucifugus	89.20	2.00e-91	328.00
IUUC-Nle-069592	Nomascus leucogenys	90.14	2.00e-90	324.00
IUUC-Ont-072173	Oreochromis niloticus	45.00	1.00e-37	149.00
IUUC-Oan-073586	Ornithorhynchus anatinus	52.94	1.00e-26	112.00
IUUC-Ocu-073996	Oryctolagus cuniculus	98.76	5.00e-92	329.00
IUUC-Oba-075150	Oryza barthii	30.59	2.90e-02	31.20
IUUC-Ola-087158	Oryzias latipes	46.25	2.00e-39	154.00
IUUC-Oga-088076	Otolemur garnettii	90.65	3.00e-97	347.00
IUUC-Ptr-091241	Pan troglodytes	96.71	7.00e-96	342.00
IUUC-Pan-091836	Papio anubis	87.79	1.00e-95	342.00
IUUC-Psi-093628	Pelodiscus sinensis	64.79	4.00e-75	273.00
IUUC-Pfo-097501	Poecilia formosa	45.28	9.00e-37	146.00
IUUC-Pop-100072	Populus trichocarpa	32.69	1.00e-02	33.90
IUUC-Pva-102796	Pteropus vampyrus	98.12	4.00e-95	340.00
IUUC-Rno-105319	Rattus norvegicus	90.14	7.00e-92	329.00
IUUC-Sha-107201	Sarcophilus harrisii	81.17	3.00e-74	270.00
IUUC-Ssc-116004	Sus scrofa	87.78	2.00e-95	341.00
IUUC-Tgu-116836	Taeniopygia guttata	61.97	1.00e-74	271.00
IUUC-Tru-118090	Takifugu rubripes	43.12	5.00e-36	144.00
IUUC-Tni-120719	Tetraodon nigroviridis	43.75	7.00e-32	130.00
IUUC-Vpa-130235	Vicugna pacos	92.09	5.00e-94	336.00
IUUC-Xtr-132610	Xenopus tropicalis	58.22	4.00e-69	253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence