iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091230

Ensembl Protein ID

ENSPTRP00000031176.5

UniProt Accession

H2QT49; H2QT49_PANTR

Genbank Protein ID

JAA00621.1; JAA14135.1; JAA27890.1; JAA43233.1

Protein Name

CD2-associated protein

Genbank Nucleotide ID

AACZ03047802; GABF01008010; GABD01005210; GABE01001506

Gene Name

CD2AP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000018244.5	ENSPTRT00000033733.5	ENSPTRP00000031176.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.40e-67	222.8	270	329

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +ke++++l+ ye++n+deLt+k+G+++++i+ke+ ++gW+kg  el+gk+G+fP+nF ++++
   Q: 270  AKEYCRTLFAYEGTNEDELTFKEGEIIHLISKETGEAGWWKG--ELNGKEGVFPDNFAVQIN 329
           689***************************************..9**************997 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MVDYIVEYDY DAVHDDELTI RVGEIIRNVK KLQEEGWLEG ELNGRRGMFP DNFVKEIKRE 60
TEFKDDSLPI KRERHGNVAS LVQRISTYGL PAGGIQPHPQ TKNIKKKTKK RQCKVLFEYI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAGGAGCAG ACGTCGGCTT CTCCCCGCGG GAGCCCCCAG CATGGGTAAG AGACTCGGGC 60
GCTTCCCGCC GCCCGTCCGG ACCTTCCAGA CCCGGGGAGG CTGTGCCCTT TCTCGGCCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028445--CD2AP
IPR001452--SH3_domain

PROSITE

PS50002--SH3

Pfam

PF00018--SH3_1
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005911--C:cell-cell junction
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0031941--C:filamentous actin
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0032911--P:negative regulation of transforming growth factor beta1 production
GO:1900182--P:positive regulation of protein localization to nucleus
GO:2000249--P:regulation of actin cytoskeleton reorganization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001574	Ailuropoda melanoleuca	89.24	0.00e+00	971.00
IUUC-Apl-003573	Anas platyrhynchos	63.66	7.00e-161	560.00
IUUC-Aca-005118	Anolis carolinensis	64.62	9.00e-168	583.00
IUUC-Ame-010657	Astyanax mexicanus	53.26	2.00e-90	326.00
IUUC-Bta-012577	Bos taurus	86.63	0.00e+00	875.00
IUUC-Cja-020010	Callithrix jacchus	94.05	0.00e+00	1005.00
IUUC-Cfa-020040	Canis familiaris	91.69	0.00e+00	961.00
IUUC-Cpo-021906	Cavia porcellus	83.54	0.00e+00	819.00
IUUC-Csa-024008	Chlorocebus sabaeus	96.56	0.00e+00	983.00
IUUC-Cho-024359	Choloepus hoffmanni	73.21	7.00e-61	228.00
IUUC-Cin-025154	Ciona intestinalis	59.26	2.00e-13	67.00
IUUC-Csv-026228	Ciona savignyi	40.37	2.00e-24	104.00
IUUC-Dre-027661	Danio rerio	54.47	1.00e-91	330.00
IUUC-Dno-029568	Dasypus novemcinctus	87.99	0.00e+00	883.00
IUUC-Dor-030286	Dipodomys ordii	78.21	0.00e+00	733.00
IUUC-Dme-032184	Drosophila melanogaster	39.02	2.00e-25	111.00
IUUC-Ete-032576	Echinops telfairi	67.70	0.00e+00	629.00
IUUC-Eca-033438	Equus caballus	90.45	0.00e+00	991.00
IUUC-Eeu-034588	Erinaceus europaeus	73.21	1.00e-153	536.00
IUUC-Fca-036597	Felis catus	91.26	0.00e+00	999.00
IUUC-Fal-037305	Ficedula albicollis	63.74	5.00e-167	580.00
IUUC-Gmo-039516	Gadus morhua	45.75	1.00e-66	247.00
IUUC-Gga-040979	Gallus gallus	66.00	2.00e-180	625.00
IUUC-Gac-041945	Gasterosteus aculeatus	52.03	7.00e-80	291.00
IUUC-Ggo-044488	Gorilla gorilla	99.69	0.00e+00	1050.00
IUUC-Hsa-045909	Homo sapiens	99.37	0.00e+00	1048.00
IUUC-Itr-049058	Ictidomys tridecemlineatus	91.87	1.00e-126	446.00
IUUC-Lch-049481	Latimeria chalumnae	55.66	6.00e-156	544.00
IUUC-Loc-052715	Lepisosteus oculatus	52.50	2.00e-143	502.00
IUUC-Laf-053444	Loxodonta africana	86.74	0.00e+00	921.00
IUUC-Mcc-054844	Macaca mulatta	96.71	0.00e+00	984.00
IUUC-Meu-056491	Macropus eugenii	65.78	0.00e+00	639.00
IUUC-Mga-060154	Meleagris gallopavo	66.36	3.00e-180	625.00
IUUC-Mmr-061099	Microcebus murinus	91.24	0.00e+00	926.00
IUUC-Mdo-062769	Monodelphis domestica	71.49	0.00e+00	775.00
IUUC-Mmu-063136	Mus musculus	86.23	0.00e+00	807.00
IUUC-Mpu-066509	Mustela putorius furo	90.71	0.00e+00	899.00
IUUC-Mlu-067174	Myotis lucifugus	87.05	0.00e+00	896.00
IUUC-Nle-070147	Nomascus leucogenys	98.59	0.00e+00	1045.00
IUUC-Opr-070752	Ochotona princeps	84.48	1.00e-175	609.00
IUUC-Ont-071810	Oreochromis niloticus	55.94	6.00e-101	361.00
IUUC-Oan-072731	Ornithorhynchus anatinus	73.53	6.00e-170	590.00
IUUC-Ocu-074331	Oryctolagus cuniculus	91.12	0.00e+00	919.00
IUUC-Ola-086404	Oryzias latipes	46.90	2.00e-92	333.00
IUUC-Oga-088200	Otolemur garnettii	91.24	0.00e+00	1012.00
IUUC-Oar-090423	Ovis aries	85.38	0.00e+00	844.00
IUUC-Pan-091823	Papio anubis	96.56	0.00e+00	982.00
IUUC-Psi-093127	Pelodiscus sinensis	63.74	2.00e-165	575.00
IUUC-Pma-094757	Petromyzon marinus	62.50	1.00e-20	92.80
IUUC-Pfo-096539	Poecilia formosa	49.26	2.00e-88	320.00
IUUC-Pab-097666	Pongo abelii	98.75	0.00e+00	1030.00
IUUC-Pca-100812	Procavia capensis	82.42	2.00e-133	469.00
IUUC-Pva-102260	Pteropus vampyrus	83.56	0.00e+00	781.00
IUUC-Rno-106038	Rattus norvegicus	85.13	0.00e+00	832.00
IUUC-Sha-106975	Sarcophilus harrisii	72.90	0.00e+00	741.00
IUUC-Sar-113386	Sorex araneus	87.80	2.00e-109	389.00
IUUC-Ssc-115569	Sus scrofa	91.09	2.00e-113	401.00
IUUC-Tgu-117104	Taeniopygia guttata	64.72	1.00e-180	626.00
IUUC-Tru-117649	Takifugu rubripes	52.45	1.00e-96	347.00
IUUC-Tsy-119258	Tarsius syrichta	83.07	0.00e+00	851.00
IUUC-Tni-120755	Tetraodon nigroviridis	45.36	6.00e-124	437.00
IUUC-Tbe-127842	Tupaia belangeri	72.06	0.00e+00	670.00
IUUC-Ttr-129205	Tursiops truncatus	89.90	0.00e+00	821.00
IUUC-Vpa-130434	Vicugna pacos	86.64	0.00e+00	791.00
IUUC-Xtr-132766	Xenopus tropicalis	57.76	4.00e-87	315.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence