iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023217

Ensembl Protein ID

ENSCSAP00000001899.1

UniProt Accession

A0A0D9QZW0; A0A0D9QZW0_CHLSB

Genbank Protein ID

ENSCSAP00000001899

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01117344

Gene Name

TRIM25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000005591.1	ENSCSAT00000003623.1	ENSCSAP00000001899.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	8.70e-09	35.7	13	54

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle+fk+ p+++pCgH f+ +Cl + w     ++    +CP Cr
   Q: 13   CSICLEPFKE-PVTTPCGHNFCGSCLnETW----AVQGAPYLCPQCR 54
           ********99.****************9**....8999999*****8 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MAQLCPLAEE LSCSICLEPF KEPVTTPCGH NFCGSCLNET WAVQGAPYLC PQCRAVYQAR 60
PQLHKNTVLC NVVEQFLQAE LAREPPADGW TPPARASAPS PGAQVACDHC LKEAAVKTCL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGCGAGGC CCGCCCAGTC CTCGCGGCCC GCCCCTCCGC GCCCCACGTG ACTTCCTGAC 60
GGCTGCAGGG ACTGCCTTTC CCGGGCTAGG TTTCGTTTCC TCCGCAGCCT CGGAGCGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005829--C:cytosol
GO:0016604--C:nuclear body
GO:0003723--F:RNA binding
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell
GO:1902187--P:negative regulation of viral release from host cell
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0006513--P:protein monoubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043627--P:response to estrogen

KEGG

csab:103242879

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002424	Ailuropoda melanoleuca	77.69	0.00e+00	981.00
IUUC-Apl-004101	Anas platyrhynchos	49.60	2.00e-168	585.00
IUUC-Aca-005025	Anolis carolinensis	50.08	8.00e-176	610.00
IUUC-Ame-010928	Astyanax mexicanus	27.69	3.00e-57	216.00
IUUC-Bta-012735	Bos taurus	73.70	0.00e+00	947.00
IUUC-Cja-019996	Callithrix jacchus	83.30	0.00e+00	735.00
IUUC-Cfa-020466	Canis familiaris	74.69	0.00e+00	968.00
IUUC-Cpo-021737	Cavia porcellus	70.14	0.00e+00	882.00
IUUC-Cho-024346	Choloepus hoffmanni	50.33	5.00e-71	261.00
IUUC-Dre-028781	Danio rerio	29.52	2.00e-62	233.00
IUUC-Dno-030082	Dasypus novemcinctus	73.86	0.00e+00	949.00
IUUC-Dor-030335	Dipodomys ordii	54.42	2.00e-133	469.00
IUUC-Ete-032923	Echinops telfairi	69.22	0.00e+00	791.00
IUUC-Eca-033411	Equus caballus	74.77	0.00e+00	954.00
IUUC-Eeu-034656	Erinaceus europaeus	72.04	7.00e-161	560.00
IUUC-Fca-035371	Felis catus	76.89	0.00e+00	976.00
IUUC-Fal-037008	Ficedula albicollis	45.60	2.00e-158	552.00
IUUC-Gmo-038668	Gadus morhua	33.76	3.00e-104	372.00
IUUC-Gga-040608	Gallus gallus	48.80	4.00e-163	568.00
IUUC-Gac-041409	Gasterosteus aculeatus	35.75	2.00e-59	224.00
IUUC-Ggo-044518	Gorilla gorilla	93.50	0.00e+00	1126.00
IUUC-Hsa-045828	Homo sapiens	94.29	0.00e+00	1166.00
IUUC-Itr-049070	Ictidomys tridecemlineatus	56.30	0.00e+00	668.00
IUUC-Lch-050478	Latimeria chalumnae	38.16	2.00e-129	456.00
IUUC-Loc-052864	Lepisosteus oculatus	37.21	4.00e-114	405.00
IUUC-Laf-054325	Loxodonta africana	76.90	1.00e-170	592.00
IUUC-Mcc-054920	Macaca mulatta	99.21	0.00e+00	1220.00
IUUC-Meu-056367	Macropus eugenii	72.83	6.00e-75	275.00
IUUC-Mga-059975	Meleagris gallopavo	49.61	2.00e-164	572.00
IUUC-Mmr-060748	Microcebus murinus	81.80	0.00e+00	1004.00
IUUC-Mdo-062904	Monodelphis domestica	57.70	0.00e+00	706.00
IUUC-Mmu-063891	Mus musculus	71.94	0.00e+00	946.00
IUUC-Mpu-066473	Mustela putorius furo	77.02	0.00e+00	993.00
IUUC-Mlu-068185	Myotis lucifugus	74.53	0.00e+00	953.00
IUUC-Nle-070177	Nomascus leucogenys	94.44	0.00e+00	1170.00
IUUC-Opr-070558	Ochotona princeps	61.50	1.00e-152	532.00
IUUC-Ont-071368	Oreochromis niloticus	35.10	9.00e-107	380.00
IUUC-Ocu-074461	Oryctolagus cuniculus	57.43	0.00e+00	664.00
IUUC-Ola-087394	Oryzias latipes	29.56	1.00e-62	234.00
IUUC-Oga-088937	Otolemur garnettii	74.96	0.00e+00	954.00
IUUC-Oar-089781	Ovis aries	74.43	0.00e+00	643.00
IUUC-Ptr-090771	Pan troglodytes	94.29	0.00e+00	1146.00
IUUC-Pan-092830	Papio anubis	98.73	0.00e+00	1213.00
IUUC-Psi-093664	Pelodiscus sinensis	52.31	2.00e-180	625.00
IUUC-Pma-094147	Petromyzon marinus	28.13	8.00e-64	238.00
IUUC-Pfo-096397	Poecilia formosa	28.95	4.00e-55	209.00
IUUC-Pab-097588	Pongo abelii	93.97	0.00e+00	1151.00
IUUC-Pca-100890	Procavia capensis	73.10	0.00e+00	887.00
IUUC-Pva-102314	Pteropus vampyrus	81.04	0.00e+00	968.00
IUUC-Pgr-103377	Puccinia graminis	39.29	2.00e-06	47.40
IUUC-Rno-105234	Rattus norvegicus	70.11	0.00e+00	908.00
IUUC-Sce-106362	Saccharomyces cerevisiae	44.93	5.00e-09	55.50
IUUC-Sha-106807	Sarcophilus harrisii	53.41	0.00e+00	655.00
IUUC-Sar-113283	Sorex araneus	58.37	4.00e-135	474.00
IUUC-Ssc-115878	Sus scrofa	80.00	5.00e-107	380.00
IUUC-Tgu-117026	Taeniopygia guttata	46.15	2.00e-130	459.00
IUUC-Tru-118624	Takifugu rubripes	26.76	1.00e-59	224.00
IUUC-Tni-120550	Tetraodon nigroviridis	26.97	6.00e-65	241.00
IUUC-Tbe-127580	Tupaia belangeri	72.51	8.00e-157	546.00
IUUC-Ttr-128648	Tursiops truncatus	72.38	0.00e+00	655.00
IUUC-Vpa-130254	Vicugna pacos	90.29	3.00e-98	352.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence