iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036642

Ensembl Protein ID

ENSFALP00000011185.1

UniProt Accession

U3K831; U3K831_FICAL

Genbank Protein ID

ENSFALP00000011185

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01020296

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000010719.1	ENSFALT00000011230.1	ENSFALP00000011185.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.40e-12	46.9	152	195

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 5    wllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           ++l ++ +SLqh CR+aI++++ +     i++LPLP +Lk+YL++++yq
   Q: 152  KPLYTSAPSLQHRCRIAINKSTNQ-----IWELPLPTRLKEYLKEYQYQ 195
           5678999***************99.....8****************986 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

PPPPPPPPPP PPPPPPPPPP PPPPPPPPPP QDAGLACGRS FQTTKEMGWY WGNMTVAEAK 60
ERLQDAPEGT FLVRDSSHSE YLLTISVKTS AGPTNLRIEY QDGKFRLDSI TCVRSRLKQF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC 60
CCCCCCCCCC CCCCCCCCCC CCCCCCCCCG CAGGACGCGG GGCTTGCTTG CGGGCGGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	72.84	2.00e-69	254.00
IUUC-Apl-003484	Anas platyrhynchos	96.64	7.00e-85	305.00
IUUC-Aca-004253	Anolis carolinensis	78.75	2.00e-74	270.00
IUUC-Ame-011267	Astyanax mexicanus	59.30	6.00e-55	206.00
IUUC-Bta-013183	Bos taurus	77.63	8.00e-70	255.00
IUUC-Cja-018862	Callithrix jacchus	77.92	1.00e-70	258.00
IUUC-Cfa-020226	Canis familiaris	78.81	1.00e-69	254.00
IUUC-Cpo-022414	Cavia porcellus	78.95	2.00e-70	258.00
IUUC-Csa-023758	Chlorocebus sabaeus	77.27	5.00e-70	256.00
IUUC-Cho-024471	Choloepus hoffmanni	71.71	2.00e-57	214.00
IUUC-Dre-028288	Danio rerio	64.56	2.00e-57	214.00
IUUC-Dno-029565	Dasypus novemcinctus	75.16	9.00e-71	259.00
IUUC-Dor-030447	Dipodomys ordii	78.15	3.00e-69	253.00
IUUC-Ete-033023	Echinops telfairi	75.16	5.00e-71	259.00
IUUC-Fca-036469	Felis catus	77.27	5.00e-70	256.00
IUUC-Gmo-039331	Gadus morhua	61.36	1.00e-30	124.00
IUUC-Gga-040809	Gallus gallus	95.39	2.00e-85	307.00
IUUC-Gac-041398	Gasterosteus aculeatus	58.39	6.00e-54	202.00
IUUC-Ggo-045341	Gorilla gorilla	77.92	2.00e-70	258.00
IUUC-Hsa-046557	Homo sapiens	73.37	5.00e-71	259.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	77.56	1.00e-70	258.00
IUUC-Lch-050160	Latimeria chalumnae	65.22	5.00e-49	186.00
IUUC-Loc-051825	Lepisosteus oculatus	62.82	2.00e-57	214.00
IUUC-Laf-053560	Loxodonta africana	77.92	2.00e-70	257.00
IUUC-Mcc-055890	Macaca mulatta	76.62	2.00e-69	254.00
IUUC-Meu-056218	Macropus eugenii	79.87	6.00e-73	266.00
IUUC-Mla-059173	Melampsora laricipopulina	29.31	4.60e+00	24.60
IUUC-Mga-059755	Meleagris gallopavo	97.32	3.00e-85	306.00
IUUC-Mmr-061387	Microcebus murinus	77.27	5.00e-70	256.00
IUUC-Mdo-062383	Monodelphis domestica	81.17	1.00e-73	268.00
IUUC-Mmu-063443	Mus musculus	77.27	7.00e-70	256.00
IUUC-Mpu-066459	Mustela putorius furo	75.32	6.00e-68	249.00
IUUC-Mlu-068040	Myotis lucifugus	73.46	3.00e-70	257.00
IUUC-Nle-069016	Nomascus leucogenys	78.21	6.00e-71	259.00
IUUC-Opr-071087	Ochotona princeps	76.32	1.00e-68	251.00
IUUC-Ont-072340	Oreochromis niloticus	58.64	6.00e-54	202.00
IUUC-Oan-073443	Ornithorhynchus anatinus	76.33	1.00e-74	271.00
IUUC-Ocu-074539	Oryctolagus cuniculus	77.12	6.00e-69	253.00
IUUC-Ola-087004	Oryzias latipes	58.23	2.00e-52	197.00
IUUC-Oga-088438	Otolemur garnettii	76.62	1.00e-69	255.00
IUUC-Oar-089932	Ovis aries	78.95	1.00e-70	258.00
IUUC-Ptr-091037	Pan troglodytes	77.92	2.00e-70	258.00
IUUC-Pan-092767	Papio anubis	77.27	6.00e-70	256.00
IUUC-Psi-093099	Pelodiscus sinensis	87.10	3.00e-77	280.00
IUUC-Pma-094671	Petromyzon marinus	44.08	7.00e-36	143.00
IUUC-Pfo-097073	Poecilia formosa	53.50	5.00e-49	186.00
IUUC-Pab-098319	Pongo abelii	74.53	1.00e-70	258.00
IUUC-Pca-101117	Procavia capensis	77.92	2.00e-70	258.00
IUUC-Pva-102117	Pteropus vampyrus	77.63	3.00e-69	253.00
IUUC-Rno-105913	Rattus norvegicus	75.97	2.00e-68	251.00
IUUC-Sha-106500	Sarcophilus harrisii	75.15	2.00e-72	264.00
IUUC-Ssc-115252	Sus scrofa	78.29	7.00e-70	256.00
IUUC-Tgu-117524	Taeniopygia guttata	96.71	5.00e-86	309.00
IUUC-Tsy-119335	Tarsius syrichta	76.82	5.00e-68	249.00
IUUC-Tni-120263	Tetraodon nigroviridis	55.56	2.00e-50	191.00
IUUC-Tbe-127915	Tupaia belangeri	77.27	8.00e-70	255.00
IUUC-Ttr-128372	Tursiops truncatus	78.29	8.00e-70	255.00
IUUC-Vpa-130422	Vicugna pacos	78.15	4.00e-69	253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence