iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055324

Ensembl Protein ID

ENSMMUP00000010265.3

UniProt Accession

G7MRS0; F7CP60; G7MRS0_MACMU

Genbank Protein ID

AFE77984.1; EHH18243.1

Protein Name

Protein kinase C and casein kinase substrate in neurons protein 1

Genbank Nucleotide ID

JSUE03030734; CM001256

Gene Name

PACSIN1; EGK_14804

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000007811.3	ENSMMUT00000010941.3	ENSMMUP00000010265.3
ENSMMUG00000007811.3	ENSMMUT00000066414.1	ENSMMUP00000053523.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.20e-15	55.8	389	444

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v++lydy++q++deL++k+Gd ++ +  ee ++gW++g + ++g+ Gl P+n+ve +
   Q: 389  RVRALYDYDGQEQDELSFKAGDELTKL-GEEDEQGWCRG-RLDSGQLGLYPANYVEAI 444
           699************************.***********.59*************975 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MSGSYDEASL APEETTDSFW EVGNYKRTVK RIDDGHRLCN DLMNCVQERA KIEKAYGQQL 60
TDWAKRWRQL IEKGPQYGSL ERAWGAIMTE ADKVSELHQE VKNNLLNEDL EKVKNWQKDA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGGGGGAG TGGGGAGGAG GCAGCGGTGG AGGGAGCTGG CTCCTGCAGT TCTGGCGCTG 60
CTGCCTTCCT GAGTGAGCAG TGGAGGGAAC CCTAGAGGAC AGAGCCCCCA GCCCGGCGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028518--PACSIN1
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0030137--C:COPI-coated vesicle
GO:0043209--C:myelin sheath
GO:0032587--C:ruffle membrane
GO:0045202--C:synapse
GO:0016301--F:kinase activity
GO:0005543--F:phospholipid binding
GO:0007015--P:actin filament organization
GO:0045806--P:negative regulation of endocytosis
GO:0048666--P:neuron development
GO:0097320--P:plasma membrane tubulation
GO:0072657--P:protein localization to membrane
GO:0048488--P:synaptic vesicle endocytosis

KEGG

mcc:718624

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001861	Ailuropoda melanoleuca	87.91	0.00e+00	779.00
IUUC-Apl-003667	Anas platyrhynchos	83.49	0.00e+00	696.00
IUUC-Aca-005229	Anolis carolinensis	81.61	0.00e+00	719.00
IUUC-Ame-011410	Astyanax mexicanus	74.44	0.00e+00	627.00
IUUC-Bta-013509	Bos taurus	94.14	0.00e+00	753.00
IUUC-Cja-019659	Callithrix jacchus	98.65	0.00e+00	838.00
IUUC-Cfa-020396	Canis familiaris	96.85	0.00e+00	800.00
IUUC-Cpo-022376	Cavia porcellus	96.85	0.00e+00	796.00
IUUC-Csa-023701	Chlorocebus sabaeus	99.77	0.00e+00	820.00
IUUC-Csv-026244	Ciona savignyi	46.05	2.00e-54	205.00
IUUC-Dre-027456	Danio rerio	75.62	0.00e+00	680.00
IUUC-Eca-033679	Equus caballus	90.38	0.00e+00	725.00
IUUC-Fca-036314	Felis catus	96.85	0.00e+00	801.00
IUUC-Fal-037300	Ficedula albicollis	85.20	0.00e+00	741.00
IUUC-Gmo-038571	Gadus morhua	68.58	3.00e-164	571.00
IUUC-Gga-040626	Gallus gallus	85.65	0.00e+00	694.00
IUUC-Gac-041445	Gasterosteus aculeatus	70.31	2.00e-169	588.00
IUUC-Ggo-045557	Gorilla gorilla	99.10	0.00e+00	814.00
IUUC-Hsa-045778	Homo sapiens	99.10	0.00e+00	814.00
IUUC-Itr-048856	Ictidomys tridecemlineatus	97.75	0.00e+00	804.00
IUUC-Lch-050070	Latimeria chalumnae	71.49	0.00e+00	672.00
IUUC-Loc-051764	Lepisosteus oculatus	79.64	0.00e+00	698.00
IUUC-Laf-054465	Loxodonta africana	94.61	0.00e+00	796.00
IUUC-Meu-056348	Macropus eugenii	90.09	0.00e+00	740.00
IUUC-Mga-059285	Meleagris gallopavo	85.68	0.00e+00	679.00
IUUC-Mmr-061367	Microcebus murinus	96.62	0.00e+00	751.00
IUUC-Mdo-062432	Monodelphis domestica	57.94	2.00e-138	485.00
IUUC-Mmu-064347	Mus musculus	95.05	0.00e+00	821.00
IUUC-Mpu-066864	Mustela putorius furo	97.07	0.00e+00	802.00
IUUC-Nle-070027	Nomascus leucogenys	99.06	0.00e+00	769.00
IUUC-Ont-072188	Oreochromis niloticus	72.71	0.00e+00	642.00
IUUC-Ocu-074297	Oryctolagus cuniculus	96.85	0.00e+00	767.00
IUUC-Ola-087188	Oryzias latipes	72.71	4.00e-163	567.00
IUUC-Oga-088856	Otolemur garnettii	97.75	0.00e+00	782.00
IUUC-Oar-090278	Ovis aries	86.94	0.00e+00	654.00
IUUC-Pan-092056	Papio anubis	99.77	0.00e+00	820.00
IUUC-Pfo-097528	Poecilia formosa	69.80	5.00e-159	553.00
IUUC-Pab-098202	Pongo abelii	99.10	0.00e+00	814.00
IUUC-Pca-100881	Procavia capensis	96.17	0.00e+00	788.00
IUUC-Pva-102181	Pteropus vampyrus	97.30	0.00e+00	800.00
IUUC-Rno-105295	Rattus norvegicus	92.34	0.00e+00	770.00
IUUC-Sha-107163	Sarcophilus harrisii	76.19	0.00e+00	652.00
IUUC-Ssc-115685	Sus scrofa	95.72	0.00e+00	791.00
IUUC-Tgu-116524	Taeniopygia guttata	78.03	0.00e+00	650.00
IUUC-Tru-118248	Takifugu rubripes	69.87	5.00e-156	543.00
IUUC-Tni-120717	Tetraodon nigroviridis	71.14	3.00e-160	558.00
IUUC-Ttr-129069	Tursiops truncatus	95.27	0.00e+00	744.00
IUUC-Xtr-132759	Xenopus tropicalis	70.92	0.00e+00	649.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence