iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098599

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01313246

Gene Name

TRIM24

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000018038.2	ENSPPYT00000021035.2	ENSPPYP00000020240.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.40e-09	38.1	827	871

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C+vC++gge    l++CekC ++fH  C+ ++  +++p+ e wiC+ Cr
   Q: 827  DWCAVCQNGGE----LLCCEKCPKVFHLSCHVPT-LTNFPSGE-WICTFCR 871
           79*********....*******************.*******8.******8 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MEVAVEKAAA AAAAASAAAS GGPSAAPSGE NEAESRQGPD SERGGEAARL NLLDTCAVCH 60
QNIQSRAPKL LPCLHSFCQR CLPAPQRYLM LPAPMLGSAE TPPPVPAPGS PVSGSSPFAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGATGAAGAG AAAGGCAGGG AGGCAAGGGC GGGCTGGGCG TATTCGACGA GCGCCGCGGC 60
GGTTGGTGAA GCGGACGGGG TGCAGCCTCC TCGGTGCGAG GAACGGTCTC CGCTGACAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR019786--Zinc_finger_PHD-type_CS
IPR000315--Znf_B-box
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS50119--ZF_BBOX
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00439--Bromodomain
PF00628--PHD
PF00643--zf-B_box

PRINTS

PR00503--BROMODOMAIN

SMART

SM00502--BBC
SM00336--BBOX
SM00297--BROMO
SM00249--PHD
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005719--C:nuclear euchromatin
GO:0005654--C:nucleoplasm
GO:0005726--C:perichromatin fibrils
GO:0003682--F:chromatin binding
GO:0034056--F:estrogen response element binding
GO:0004672--F:protein kinase activity
GO:0043565--F:sequence-specific DNA binding
GO:0003713--F:transcription coactivator activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0055074--P:calcium ion homeostasis
GO:0071391--P:cellular response to estrogen stimulus
GO:0008285--P:negative regulation of cell proliferation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0046777--P:protein autophosphorylation
GO:0030163--P:protein catabolic process
GO:0042981--P:regulation of apoptotic process
GO:0031647--P:regulation of protein stability
GO:1901796--P:regulation of signal transduction by p53 class mediator
GO:0070562--P:regulation of vitamin D receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001838	Ailuropoda melanoleuca	95.91	0.00e+00	1668.00
IUUC-Apl-003697	Anas platyrhynchos	79.72	0.00e+00	1271.00
IUUC-Bta-013282	Bos taurus	95.25	0.00e+00	1707.00
IUUC-Cel-018523	Caenorhabditis elegans	39.81	1.00e-14	76.30
IUUC-Cja-018920	Callithrix jacchus	97.16	0.00e+00	1753.00
IUUC-Cfa-020984	Canis familiaris	96.57	0.00e+00	1723.00
IUUC-Cpo-022035	Cavia porcellus	94.51	0.00e+00	1579.00
IUUC-Csa-024208	Chlorocebus sabaeus	98.57	0.00e+00	1775.00
IUUC-Cho-024413	Choloepus hoffmanni	65.34	5.00e-162	565.00
IUUC-Dno-029145	Dasypus novemcinctus	96.12	0.00e+00	1602.00
IUUC-Dor-030396	Dipodomys ordii	93.66	0.00e+00	1220.00
IUUC-Ete-032414	Echinops telfairi	85.08	0.00e+00	885.00
IUUC-Eca-033489	Equus caballus	96.56	0.00e+00	1576.00
IUUC-Eeu-034654	Erinaceus europaeus	94.05	0.00e+00	763.00
IUUC-Fca-035844	Felis catus	92.37	0.00e+00	1444.00
IUUC-Fal-036735	Ficedula albicollis	79.26	0.00e+00	1284.00
IUUC-Gga-041124	Gallus gallus	77.95	0.00e+00	1342.00
IUUC-Ggo-044542	Gorilla gorilla	98.63	0.00e+00	1772.00
IUUC-Hsa-046785	Homo sapiens	98.53	0.00e+00	1768.00
IUUC-Itr-048262	Ictidomys tridecemlineatus	95.98	0.00e+00	1669.00
IUUC-Laf-054279	Loxodonta africana	92.81	0.00e+00	1650.00
IUUC-Mcc-055668	Macaca mulatta	98.57	0.00e+00	1777.00
IUUC-Meu-056195	Macropus eugenii	77.78	0.00e+00	796.00
IUUC-Mga-059272	Meleagris gallopavo	79.19	0.00e+00	1258.00
IUUC-Mmr-060936	Microcebus murinus	95.98	0.00e+00	1722.00
IUUC-Mdo-062848	Monodelphis domestica	87.61	0.00e+00	1563.00
IUUC-Mmu-063598	Mus musculus	92.11	0.00e+00	1663.00
IUUC-Mpu-066272	Mustela putorius furo	96.46	0.00e+00	1589.00
IUUC-Mlu-067958	Myotis lucifugus	93.56	0.00e+00	1557.00
IUUC-Nle-069375	Nomascus leucogenys	98.67	0.00e+00	1777.00
IUUC-Opr-070836	Ochotona princeps	82.74	0.00e+00	669.00
IUUC-Oan-073393	Ornithorhynchus anatinus	80.39	0.00e+00	1013.00
IUUC-Ocu-074873	Oryctolagus cuniculus	93.58	0.00e+00	1534.00
IUUC-Oga-088692	Otolemur garnettii	95.79	0.00e+00	1707.00
IUUC-Oar-090160	Ovis aries	95.59	0.00e+00	1561.00
IUUC-Ptr-090756	Pan troglodytes	98.53	0.00e+00	1768.00
IUUC-Pan-091719	Papio anubis	98.48	0.00e+00	1771.00
IUUC-Psi-093433	Pelodiscus sinensis	80.15	0.00e+00	1319.00
IUUC-Pca-100540	Procavia capensis	86.05	0.00e+00	941.00
IUUC-Pva-102478	Pteropus vampyrus	89.14	0.00e+00	1538.00
IUUC-Rno-105478	Rattus norvegicus	78.18	0.00e+00	652.00
IUUC-Sha-106740	Sarcophilus harrisii	83.70	0.00e+00	1344.00
IUUC-Sar-113615	Sorex araneus	94.76	0.00e+00	1399.00
IUUC-Tgu-117368	Taeniopygia guttata	76.50	0.00e+00	1362.00
IUUC-Tsy-118904	Tarsius syrichta	97.09	0.00e+00	1610.00
IUUC-Tbe-127354	Tupaia belangeri	83.15	0.00e+00	717.00
IUUC-Ttr-128983	Tursiops truncatus	92.98	0.00e+00	1191.00
IUUC-Vpa-130420	Vicugna pacos	93.97	0.00e+00	1545.00
IUUC-Vvi-131561	Vitis vinifera	47.17	3.00e-12	67.40

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence