iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066737

Ensembl Protein ID

ENSMPUP00000006611.1

UniProt Accession

M3Y5L0; M3Y5L0_MUSPF

Genbank Protein ID

ENSMPUP00000006611

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01024535

Gene Name

KEAP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000006665.1	ENSMPUT00000006724.1	ENSMPUP00000006611.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.90e-17	61.8	77	148
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.00e-09	35.1	181	211

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvv....g.geeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv+l+v    +   +f ahk+vLa+sS+vF+a+f+++l+e+   + v i+++ p+v++ l++F Yt ++++ 
   Q: 77   CDVTLQVkyedApAAQFMAHKVVLASSSPVFKAMFTNGLREQG-MEVVSIEGIHPKVMERLIEFAYTASISMG 148
           8******66652699**************************98.***********************998875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++N++gi  fA++ +c +L+++a+++i  hF
   Q: 181  PSNAIGIANFAEQIGCAELHQRAREYIYMHF 211
           89****************************9 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MQPEPRPSGA GARTRFLPLR SQRPEGAGDT VMYASTECKA EVTPSQHGNR TFSYTLEDHT 60
KQAFGIMNEL RLSQQLCDVT LQVKYEDAPA AQFMAHKVVL ASSSPVFKAM FTNGLREQGM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNGGCC 60
GGGGGCCGCG GGGACTTTTA TTCTGACACG GCCGGCGCCC GGCTCTGCTT AGTCATGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR030563--KEAP1
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005884--C:actin filament
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005815--C:microtubule organizing center
GO:0030496--C:midbody
GO:0005654--C:nucleoplasm
GO:0071353--P:cellular response to interleukin-4
GO:0001701--P:in utero embryonic development
GO:0010499--P:proteasomal ubiquitin-independent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0045604--P:regulation of epidermal cell differentiation
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001377	Ailuropoda melanoleuca	96.79	0.00e+00	1262.00
IUUC-Aca-005389	Anolis carolinensis	84.82	0.00e+00	1060.00
IUUC-Aor-010180	Aspergillus oryzae	24.57	8.00e-10	57.80
IUUC-Ame-010749	Astyanax mexicanus	78.82	0.00e+00	953.00
IUUC-Bta-013505	Bos taurus	95.51	0.00e+00	1245.00
IUUC-Cja-018823	Callithrix jacchus	94.39	0.00e+00	1230.00
IUUC-Cfa-021202	Canis familiaris	96.47	0.00e+00	1256.00
IUUC-Cpo-021830	Cavia porcellus	92.48	0.00e+00	802.00
IUUC-Csa-023728	Chlorocebus sabaeus	94.55	0.00e+00	1229.00
IUUC-Cin-025195	Ciona intestinalis	55.73	0.00e+00	669.00
IUUC-Csv-026155	Ciona savignyi	54.01	2.00e-178	618.00
IUUC-Dre-027388	Danio rerio	78.07	0.00e+00	931.00
IUUC-Dno-029066	Dasypus novemcinctus	83.20	0.00e+00	1052.00
IUUC-Dor-030674	Dipodomys ordii	91.00	0.00e+00	791.00
IUUC-Dme-032165	Drosophila melanogaster	49.82	5.00e-160	558.00
IUUC-Ete-032255	Echinops telfairi	94.87	4.00e-89	321.00
IUUC-Eca-034381	Equus caballus	91.63	0.00e+00	1174.00
IUUC-Eeu-034791	Erinaceus europaeus	92.36	0.00e+00	819.00
IUUC-Fca-036067	Felis catus	96.15	0.00e+00	1254.00
IUUC-Gmo-039691	Gadus morhua	77.68	0.00e+00	931.00
IUUC-Gga-040266	Gallus gallus	78.86	0.00e+00	984.00
IUUC-Gac-041866	Gasterosteus aculeatus	78.21	0.00e+00	938.00
IUUC-Ggo-044719	Gorilla gorilla	95.03	0.00e+00	1236.00
IUUC-Hsa-046255	Homo sapiens	95.03	0.00e+00	1236.00
IUUC-Itr-048457	Ictidomys tridecemlineatus	94.71	0.00e+00	1229.00
IUUC-Lch-049646	Latimeria chalumnae	84.27	0.00e+00	1025.00
IUUC-Loc-052296	Lepisosteus oculatus	56.38	5.00e-180	624.00
IUUC-Laf-054579	Loxodonta africana	94.87	0.00e+00	1236.00
IUUC-Mcc-055315	Macaca mulatta	94.55	0.00e+00	1229.00
IUUC-Meu-056288	Macropus eugenii	87.66	0.00e+00	1088.00
IUUC-Mmr-061639	Microcebus murinus	95.03	0.00e+00	1244.00
IUUC-Mdo-062072	Monodelphis domestica	92.15	0.00e+00	1191.00
IUUC-Mmu-063622	Mus musculus	91.19	0.00e+00	1192.00
IUUC-Mlu-068173	Myotis lucifugus	95.67	0.00e+00	1246.00
IUUC-Nle-069336	Nomascus leucogenys	54.69	7.00e-168	583.00
IUUC-Opr-070432	Ochotona princeps	94.16	0.00e+00	1182.00
IUUC-Ont-072160	Oreochromis niloticus	75.74	0.00e+00	932.00
IUUC-Oan-072691	Ornithorhynchus anatinus	81.36	0.00e+00	951.00
IUUC-Ocu-073798	Oryctolagus cuniculus	93.59	0.00e+00	1226.00
IUUC-Ola-086367	Oryzias latipes	73.57	0.00e+00	902.00
IUUC-Oga-088231	Otolemur garnettii	95.19	0.00e+00	1241.00
IUUC-Oar-089227	Ovis aries	94.23	0.00e+00	1220.00
IUUC-Ptr-091460	Pan troglodytes	95.03	0.00e+00	1236.00
IUUC-Pan-092713	Papio anubis	94.55	0.00e+00	1229.00
IUUC-Ppa-095249	Physcomitrella patens	31.11	4.00e-15	75.90
IUUC-Pfo-096468	Poecilia formosa	79.44	0.00e+00	942.00
IUUC-Pab-098357	Pongo abelii	95.19	0.00e+00	1239.00
IUUC-Pca-100837	Procavia capensis	93.43	0.00e+00	1212.00
IUUC-Pva-103249	Pteropus vampyrus	93.59	0.00e+00	1189.00
IUUC-Rno-106086	Rattus norvegicus	90.71	0.00e+00	1181.00
IUUC-Sha-107245	Sarcophilus harrisii	91.67	0.00e+00	1186.00
IUUC-Sar-112985	Sorex araneus	93.91	0.00e+00	1223.00
IUUC-Ssc-115756	Sus scrofa	96.47	0.00e+00	1256.00
IUUC-Tgu-116838	Taeniopygia guttata	53.93	1.00e-118	419.00
IUUC-Tru-117644	Takifugu rubripes	77.34	0.00e+00	955.00
IUUC-Tni-120245	Tetraodon nigroviridis	78.91	0.00e+00	943.00
IUUC-Tbe-127472	Tupaia belangeri	91.84	1.00e-136	480.00
IUUC-Ttr-128953	Tursiops truncatus	97.77	0.00e+00	722.00
IUUC-Vpa-130683	Vicugna pacos	95.78	0.00e+00	1123.00
IUUC-Xtr-132827	Xenopus tropicalis	76.09	0.00e+00	929.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence