iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Rno-105197

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Probable E3 ubiquitin-protein ligase MARCH10; Membrane-associated RING finger protein 10; Membrane-associated RING-CH protein X; RING finger protein 190; RING-type E3 ubiquitin transferase MARCH10

Genbank Nucleotide ID

BC083567

Gene Name

March10; Rnf190

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000007084.7	ENSRNOT00000009316.7	ENSRNOP00000009316.5
ENSRNOG00000007084.7	ENSRNOT00000090662.1	ENSRNOP00000072446.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	60.56	0.00e+00	750.00	IUUC-Hsa-045953

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Functional Description
(View)

E3 ubiquitin-protein ligase (Probable). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MLHEARDRQK FVSDVQYLRD MQHKVDSEYQ ACLKRQEHKK EPNEKKQEQL WGKDTSDRSR 60
FSSGSSCKQS SGEEDSLSEA RLATKAPTAK CEPKLPAIDQ TSVKQKHKGT MTLKKPEKVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGAACCTCCT CATCCCTGGC CCTTACCCTC TCCTTAGCAT GGCGTTTCAC ACGGATTTCT 60
AAAAACAAAA GCTTGGTCCA GTGCTTTGTC ACCAGAGGCT TACAACAGAG GTACGCATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51292--ZF_RING_CH

Pfam

PF12906--RINGv

SMART

SM00744--RINGv

Gene Ontology

GO:0016740--F:transferase activity
GO:0008270--F:zinc ion binding
GO:0016567--P:protein ubiquitination

KEGG

rno:303596

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002345	Ailuropoda melanoleuca	61.21	0.00e+00	792.00
IUUC-Aca-004250	Anolis carolinensis	42.27	1.00e-60	227.00
IUUC-Bta-013138	Bos taurus	59.34	0.00e+00	717.00
IUUC-Cja-019793	Callithrix jacchus	57.58	0.00e+00	679.00
IUUC-Cpo-021565	Cavia porcellus	56.18	5.00e-107	381.00
IUUC-Csa-024222	Chlorocebus sabaeus	55.70	3.00e-133	469.00
IUUC-Cho-024306	Choloepus hoffmanni	59.77	3.00e-101	362.00
IUUC-Dor-030702	Dipodomys ordii	55.44	1.00e-176	613.00
IUUC-Ete-033007	Echinops telfairi	40.91	3.00e-105	375.00
IUUC-Eca-034038	Equus caballus	64.14	0.00e+00	825.00
IUUC-Fca-035583	Felis catus	62.45	0.00e+00	768.00
IUUC-Ggo-045166	Gorilla gorilla	59.09	0.00e+00	694.00
IUUC-Hsa-045953	Homo sapiens	59.34	0.00e+00	716.00
IUUC-Itr-048662	Ictidomys tridecemlineatus	64.75	0.00e+00	811.00
IUUC-Laf-054183	Loxodonta africana	61.17	0.00e+00	650.00
IUUC-Meu-056145	Macropus eugenii	41.31	9.00e-44	172.00
IUUC-Mmr-061386	Microcebus murinus	60.63	0.00e+00	721.00
IUUC-Mpu-066649	Mustela putorius furo	62.01	0.00e+00	751.00
IUUC-Mlu-067404	Myotis lucifugus	57.09	0.00e+00	682.00
IUUC-Nle-070167	Nomascus leucogenys	57.25	0.00e+00	672.00
IUUC-Opr-070961	Ochotona princeps	54.37	7.00e-168	584.00
IUUC-Ocu-074491	Oryctolagus cuniculus	54.19	0.00e+00	652.00
IUUC-Oar-089821	Ovis aries	57.50	0.00e+00	719.00
IUUC-Ptr-090789	Pan troglodytes	59.21	0.00e+00	716.00
IUUC-Pan-092125	Papio anubis	58.75	0.00e+00	683.00
IUUC-Pab-098370	Pongo abelii	58.48	0.00e+00	702.00
IUUC-Pca-100716	Procavia capensis	53.09	7.00e-175	607.00
IUUC-Pva-102277	Pteropus vampyrus	61.76	0.00e+00	749.00
IUUC-Sha-107288	Sarcophilus harrisii	52.86	3.00e-159	555.00
IUUC-Ssc-115620	Sus scrofa	60.27	0.00e+00	661.00
IUUC-Tbe-127829	Tupaia belangeri	62.13	0.00e+00	701.00
IUUC-Ttr-128353	Tursiops truncatus	65.04	2.00e-107	383.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence