iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045534

Ensembl Protein ID

ENSGGOP00000018950.1

UniProt Accession

G3RT25; G3RT25_GORGO

Protein Name

Uncharacterized protein

Gene Name

BCAR1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000010661.2	ENSGGOT00000027075.1	ENSGGOP00000018950.1
ENSGGOG00000010661.2	ENSGGOT00000010705.2	ENSGGOP00000010400.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.70e-11	43.2	54	104

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqd.egWlkgvkelegkrGlfPen 57
            ++lyd  a++ deL+++kGd+++v+e+++q   gW+ +   l+g++G++P n
   Q: 54   AKALYDNVAESPDELSFRKGDIMTVLEQDTQGlDGWWLC--SLHGRQGIVPGN 104
           589***********************666654389****..9*********98 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MPAKPFLSSV LLSCKVLDFS GPGPQGTGQP CFCGHWAEGQ GGPPEPAGGP NVLAKALYDN 60
VAESPDELSF RKGDIMTVLE QDTQGLDGWW LCSLHGRQGI VPGNRLKILV GMYDKKPAGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTGCCA AGCCCTTCCT CTCTTCTGTT CTGCTCTCCT GTAAAGTTCT GGACTTCTCT 60
GGCCCAGGGC CTCAGGGGAC TGGCCAGCCC TGCTTCTGTG GGCACTGGGC AGAGGGACAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028848--BCAR1
IPR021901--CAS_DUF3513
IPR014928--Serine_rich
IPR001452--SH3_domain
IPR013315--Spectrin_alpha_SH3
IPR015224--Talin_cent

PROSITE

PS50002--SH3

Pfam

PF12026--DUF3513
PF08824--Serine_rich
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN
PR01887--SPECTRNALPHA

SMART

SM00326--SH3

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005737--C:cytoplasm
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0004871--F:signal transducer activity
GO:0007015--P:actin filament organization
GO:0050853--P:B cell receptor signaling pathway
GO:0060326--P:cell chemotaxis
GO:0035729--P:cellular response to hepatocyte growth factor stimulus
GO:0007186--P:G-protein coupled receptor signaling pathway
GO:0048012--P:hepatocyte growth factor receptor signaling pathway
GO:0007229--P:integrin-mediated signaling pathway
GO:0048008--P:platelet-derived growth factor receptor signaling pathway
GO:0010595--P:positive regulation of endothelial cell migration
GO:0048010--P:vascular endothelial growth factor receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001208	Ailuropoda melanoleuca	90.18	0.00e+00	1194.00
IUUC-Apl-003391	Anas platyrhynchos	38.01	2.00e-142	499.00
IUUC-Aca-004548	Anolis carolinensis	37.57	6.00e-141	494.00
IUUC-Ame-010839	Astyanax mexicanus	27.09	1.00e-34	141.00
IUUC-Bta-013197	Bos taurus	82.74	0.00e+00	1153.00
IUUC-Cja-018921	Callithrix jacchus	94.83	0.00e+00	1412.00
IUUC-Cfa-020772	Canis familiaris	90.56	0.00e+00	1301.00
IUUC-Cpo-022455	Cavia porcellus	90.18	0.00e+00	1290.00
IUUC-Csa-023660	Chlorocebus sabaeus	97.46	0.00e+00	1416.00
IUUC-Cin-025595	Ciona intestinalis	27.64	4.00e-67	249.00
IUUC-Dre-028389	Danio rerio	54.07	0.00e+00	838.00
IUUC-Dno-028907	Dasypus novemcinctus	87.30	0.00e+00	1165.00
IUUC-Dor-030300	Dipodomys ordii	93.82	2.00e-164	573.00
IUUC-Dme-031580	Drosophila melanogaster	28.28	1.00e-40	161.00
IUUC-Ete-032641	Echinops telfairi	93.84	1.00e-129	457.00
IUUC-Eca-033297	Equus caballus	92.15	0.00e+00	1317.00
IUUC-Eeu-035356	Erinaceus europaeus	84.62	0.00e+00	928.00
IUUC-Fca-036302	Felis catus	91.11	0.00e+00	1208.00
IUUC-Fal-036729	Ficedula albicollis	64.21	0.00e+00	1058.00
IUUC-Gga-040285	Gallus gallus	62.55	0.00e+00	1003.00
IUUC-Gac-041754	Gasterosteus aculeatus	27.70	3.00e-25	110.00
IUUC-Hsa-046672	Homo sapiens	98.91	0.00e+00	1496.00
IUUC-Itr-048045	Ictidomys tridecemlineatus	92.41	0.00e+00	1303.00
IUUC-Lch-049837	Latimeria chalumnae	59.44	0.00e+00	919.00
IUUC-Loc-052010	Lepisosteus oculatus	54.93	0.00e+00	848.00
IUUC-Laf-053978	Loxodonta africana	91.00	0.00e+00	1229.00
IUUC-Mcc-055551	Macaca mulatta	95.96	0.00e+00	1428.00
IUUC-Meu-056006	Macropus eugenii	67.24	0.00e+00	961.00
IUUC-Mga-060136	Meleagris gallopavo	40.62	2.00e-154	540.00
IUUC-Mmr-061269	Microcebus murinus	91.20	0.00e+00	1352.00
IUUC-Mdo-062756	Monodelphis domestica	25.92	1.00e-31	131.00
IUUC-Mmu-063741	Mus musculus	90.57	0.00e+00	1327.00
IUUC-Mpu-066694	Mustela putorius furo	90.53	0.00e+00	1227.00
IUUC-Mlu-067377	Myotis lucifugus	89.03	0.00e+00	1252.00
IUUC-Nle-069243	Nomascus leucogenys	92.40	0.00e+00	763.00
IUUC-Opr-070611	Ochotona princeps	85.01	0.00e+00	1158.00
IUUC-Ont-071724	Oreochromis niloticus	52.32	0.00e+00	785.00
IUUC-Oan-073477	Ornithorhynchus anatinus	50.48	6.00e-46	176.00
IUUC-Ocu-074436	Oryctolagus cuniculus	80.60	0.00e+00	1106.00
IUUC-Ola-086487	Oryzias latipes	49.29	0.00e+00	721.00
IUUC-Oga-088966	Otolemur garnettii	90.92	0.00e+00	1381.00
IUUC-Oar-089394	Ovis aries	80.07	3.00e-131	462.00
IUUC-Ptr-090896	Pan troglodytes	99.02	0.00e+00	1528.00
IUUC-Pan-092021	Papio anubis	97.11	0.00e+00	1384.00
IUUC-Psi-094075	Pelodiscus sinensis	28.93	2.00e-73	270.00
IUUC-Pfo-097206	Poecilia formosa	28.37	1.00e-29	124.00
IUUC-Pab-098732	Pongo abelii	93.76	0.00e+00	1299.00
IUUC-Pca-100841	Procavia capensis	88.81	0.00e+00	628.00
IUUC-Pva-102291	Pteropus vampyrus	84.83	0.00e+00	874.00
IUUC-Rno-105602	Rattus norvegicus	91.15	0.00e+00	1339.00
IUUC-Sha-106605	Sarcophilus harrisii	63.44	6.00e-88	318.00
IUUC-Spo-108375	Schizosaccharomyces pombe	41.82	1.00e-07	53.10
IUUC-Ssc-116113	Sus scrofa	88.91	0.00e+00	1207.00
IUUC-Tgu-117420	Taeniopygia guttata	37.79	5.00e-144	504.00
IUUC-Tru-118044	Takifugu rubripes	46.43	5.00e-31	129.00
IUUC-Ttr-128533	Tursiops truncatus	88.57	0.00e+00	1202.00
IUUC-Xtr-132220	Xenopus tropicalis	31.20	1.00e-84	308.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence