iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000012824.2	ENSPANT00000017001.2	ENSPANP00000010404.1
ENSPANG00000012824.2	ENSPANT00000025050.1	ENSPANP00000006993.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.10e-113	379.0	309	930

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+e++l+  + e+ln +np ++kge+++++++l+++ w+++++++ p+ ++++++++a++f gy+
   Q: 309  CGLTNLGNTCFMNSALQCLSNVPQLTEYFLNnCYLEELNFRNPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKNKVGHFASQFLGYQ 397
           7******************************99******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           q+D+qE+l+flld+l+e+l++ k+k++ e+++++ +  ++    a++++k++n+s+i+d+F+g +ks+++c++c+nvs++++pf++ls+
   Q: 398  QHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVaqeAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSV 486
           *****************************998874333322555********************************************* PP
   S: 175  pvpgkeetkke.............................................................................. 185
           p+p ++++ +e                                                                              
   Q: 487  PLPISHKRVLEvffipmdprrkpeqhrlvvpkkgkisdlcvalskhtgispermmvadvfshrfyklyqleeplssildrddifvyevs 575
           ******99888****************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 576  grieaiegsredivvpvylrertpardynnsyyglmlfghpllvsvprdrftweglynvlmyrlsryvskpnsddeddgdekeddeedk 664
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 665  ddvpgpstggslrdpepeqagpssgvtnrcpflldnclgtsqwpprrrrkqlftlqtvnsngtsdrttspeevhaqpyiaidwepemkk 753
           ***************************************************************************************** PP
   S: 186  ..........................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
                                      lq+c+e ft+ e+le+en +yc++ck++q a+kkl+l+ lPe+Li+hLkRfs+++   srek
   Q: 754  ryydeveaegyvkhdcvgyvmkkapvRLQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRFSYTK--FSREK 840
           ******************************************************************************8866..89*** PP
   S: 249  inkkvefple.Ldlspfctspeekqke.kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlf 334
           +++ vefp++ Ld s+f+++p+++++   +kY+Liav +H+G+++ GHY++++ n ++g+W +fdD++V++v+e+++++   + aYvlf
   Q: 841  LDTLVEFPIRdLDFSEFVIQPQNESNPeLYKYDLIAVSNHYGGMRDGHYTTFACNkDSGQWHYFDDNSVSPVNENQIES---KAAYVLF 926
           *****************9999887764489*********************988834566*******************...******* PP
   S: 335  Ykrr 338
           Y+r+
   Q: 927  YQRQ 930
           **96 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MAVAPRLFGG LCFRFRDQNP EVAVEGRLPI SHSCVGCRGE RTAMATVAAN PAAAAAAVAA 60
AVAVAEDREP QREELPGLDS QWRQIENGES GRERPLRAGE SWFLVEKHWY KQWEAYVQGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGTAG CCCCGCGACT GTTTGGGGGG CTCTGCTTCC GTTTCCGGGA CCAGAATCCG 60
GAAGTGGCTG TTGAGGGGCG TCTTCCAATC TCGCACAGCT GCGTTGGCTG TAGAGGAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001760	Ailuropoda melanoleuca	83.18	0.00e+00	1509.00
IUUC-Aca-004532	Anolis carolinensis	64.43	0.00e+00	1149.00
IUUC-Aly-006044	Arabidopsis lyrata	35.89	5.00e-137	481.00
IUUC-Ago-007911	Ashbya gossypii	33.06	3.00e-64	240.00
IUUC-Afu-008878	Aspergillus fumigatus	39.15	8.00e-55	209.00
IUUC-Ani-009479	Aspergillus nidulans	42.35	1.00e-52	202.00
IUUC-Aor-009949	Aspergillus oryzae	36.15	1.00e-52	202.00
IUUC-Ate-010323	Aspergillus terreus	36.87	6.00e-56	213.00
IUUC-Bta-013284	Bos taurus	83.31	0.00e+00	1481.00
IUUC-Cja-019746	Callithrix jacchus	95.66	0.00e+00	1702.00
IUUC-Cfa-020134	Canis familiaris	83.26	0.00e+00	1592.00
IUUC-Cpo-022535	Cavia porcellus	82.60	0.00e+00	1558.00
IUUC-Csa-023828	Chlorocebus sabaeus	98.65	0.00e+00	1853.00
IUUC-Dre-027398	Danio rerio	60.31	0.00e+00	731.00
IUUC-Dno-028853	Dasypus novemcinctus	83.84	0.00e+00	1305.00
IUUC-Dor-030384	Dipodomys ordii	83.90	0.00e+00	1586.00
IUUC-Eca-033271	Equus caballus	83.96	0.00e+00	1511.00
IUUC-Fca-036012	Felis catus	83.52	0.00e+00	1544.00
IUUC-Gac-042574	Gasterosteus aculeatus	54.51	0.00e+00	889.00
IUUC-Hsa-046551	Homo sapiens	98.03	0.00e+00	1843.00
IUUC-Itr-048915	Ictidomys tridecemlineatus	84.38	0.00e+00	1600.00
IUUC-Kpa-049332	Komagataella pastoris	34.14	2.00e-73	270.00
IUUC-Laf-054561	Loxodonta africana	79.65	0.00e+00	1565.00
IUUC-Mcc-054881	Macaca mulatta	98.55	0.00e+00	1853.00
IUUC-Meu-056749	Macropus eugenii	77.65	0.00e+00	883.00
IUUC-Mla-058848	Melampsora laricipopulina	42.27	1.00e-71	265.00
IUUC-Mvi-060324	Microbotryum violaceum	31.03	6.00e-80	293.00
IUUC-Mmr-061400	Microcebus murinus	91.23	0.00e+00	1667.00
IUUC-Mdo-062470	Monodelphis domestica	77.99	0.00e+00	773.00
IUUC-Mmu-063241	Mus musculus	81.84	0.00e+00	1507.00
IUUC-Mpu-066507	Mustela putorius furo	83.76	0.00e+00	1558.00
IUUC-Mlu-066961	Myotis lucifugus	77.47	0.00e+00	1389.00
IUUC-Nfi-068330	Neosartorya fischeri	39.15	8.00e-55	209.00
IUUC-Nle-069284	Nomascus leucogenys	98.22	0.00e+00	1768.00
IUUC-Ont-071847	Oreochromis niloticus	57.72	0.00e+00	971.00
IUUC-Oan-073387	Ornithorhynchus anatinus	69.68	0.00e+00	1204.00
IUUC-Ocu-074066	Oryctolagus cuniculus	87.18	0.00e+00	1641.00
IUUC-Oga-088424	Otolemur garnettii	90.65	0.00e+00	1648.00
IUUC-Oar-089732	Ovis aries	79.15	0.00e+00	1492.00
IUUC-Pab-098779	Pongo abelii	89.71	0.00e+00	1546.00
IUUC-Pca-100851	Procavia capensis	78.60	0.00e+00	920.00
IUUC-Pva-103244	Pteropus vampyrus	81.83	0.00e+00	1494.00
IUUC-Ptt-103847	Puccinia triticina	34.94	2.00e-64	241.00
IUUC-Rno-105100	Rattus norvegicus	80.95	0.00e+00	1509.00
IUUC-Sha-107502	Sarcophilus harrisii	76.30	0.00e+00	877.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	36.40	2.00e-82	300.00
IUUC-Spo-108291	Schizosaccharomyces pombe	33.56	2.00e-75	277.00
IUUC-Ssc-116345	Sus scrofa	83.61	0.00e+00	1555.00
IUUC-Tru-117788	Takifugu rubripes	56.37	0.00e+00	926.00
IUUC-Tsy-119414	Tarsius syrichta	83.18	0.00e+00	1238.00
IUUC-Tni-120107	Tetraodon nigroviridis	48.98	5.00e-157	548.00
IUUC-Tre-121888	Trichoderma reesei	43.75	2.00e-63	238.00
IUUC-Tvi-122422	Trichoderma virens	41.54	6.00e-58	220.00
IUUC-Tae-125515	Triticum aestivum	33.16	1.00e-122	434.00
IUUC-Tbe-128081	Tupaia belangeri	91.26	0.00e+00	1015.00
IUUC-Ttr-128502	Tursiops truncatus	79.88	0.00e+00	1495.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence