iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000005633.7	ENSRNOT00000088600.1	ENSRNOP00000068611.1
ENSRNOG00000005633.7	ENSRNOT00000041639.2	ENSRNOP00000042665.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.00e-12	48.6	25	90

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +D++lvv g+ f+ahk vLaa S++F++lf++  ++++     ++     +   ++l+F+Yt++ld+n
   Q: 25   CDCMLVVRGVCFKAHKNVLAAFSQYFRSLFQNSSSQKNDIFHLDV--KNVSGIGQILDFMYTSRLDLN 90
           8*****************************988776654444444..48999**************98 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MDPVAIHSCH LLQQLREQRI QGLLCDCMLV VRGVCFKAHK NVLAAFSQYF RSLFQNSSSQ 60
KNDIFHLDVK NVSGIGQILD FMYTSRLDLN QDNIQVMLDT AQCLQVQNVL NLCHTFLKSA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGACGAGCTG CCGAGGGGGC GTTGTCGGAA TGGTTCCGAG GCGGTTGGAG TCCTGCAGTT 60
GACACCAGTT TGACGAGAAC GAGTGTCAAG GAGGCGGCCG GGCGAGAGCG GCCTCCGTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0015630--C:microtubule cytoskeleton
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0007050--P:cell cycle arrest
GO:0008285--P:negative regulation of cell proliferation
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002380	Ailuropoda melanoleuca	68.49	0.00e+00	975.00
IUUC-Apl-003402	Anas platyrhynchos	61.67	0.00e+00	939.00
IUUC-Aca-005251	Anolis carolinensis	53.47	0.00e+00	747.00
IUUC-Ame-011624	Astyanax mexicanus	47.70	2.00e-145	509.00
IUUC-Bta-013500	Bos taurus	69.43	0.00e+00	974.00
IUUC-Cja-019265	Callithrix jacchus	71.26	0.00e+00	1035.00
IUUC-Cfa-020468	Canis familiaris	68.36	0.00e+00	978.00
IUUC-Cpo-021937	Cavia porcellus	69.01	0.00e+00	932.00
IUUC-Csa-023216	Chlorocebus sabaeus	72.06	0.00e+00	1051.00
IUUC-Dre-028348	Danio rerio	61.79	1.00e-96	347.00
IUUC-Dno-029339	Dasypus novemcinctus	66.54	0.00e+00	959.00
IUUC-Dor-030277	Dipodomys ordii	74.31	2.00e-88	320.00
IUUC-Dme-032129	Drosophila melanogaster	50.63	7.00e-20	93.60
IUUC-Eca-033669	Equus caballus	71.00	0.00e+00	1037.00
IUUC-Fca-035639	Felis catus	64.48	0.00e+00	865.00
IUUC-Fal-037462	Ficedula albicollis	60.21	0.00e+00	831.00
IUUC-Gmo-039476	Gadus morhua	44.81	7.00e-148	517.00
IUUC-Gac-041549	Gasterosteus aculeatus	52.58	5.00e-158	551.00
IUUC-Ggo-044866	Gorilla gorilla	72.10	0.00e+00	1044.00
IUUC-Hsa-045928	Homo sapiens	72.32	0.00e+00	1050.00
IUUC-Itr-048707	Ictidomys tridecemlineatus	72.03	0.00e+00	1015.00
IUUC-Lch-050388	Latimeria chalumnae	52.89	0.00e+00	778.00
IUUC-Loc-052002	Lepisosteus oculatus	50.33	0.00e+00	676.00
IUUC-Laf-054184	Loxodonta africana	67.10	0.00e+00	955.00
IUUC-Mcc-055715	Macaca mulatta	71.93	0.00e+00	1048.00
IUUC-Mga-059724	Meleagris gallopavo	61.67	0.00e+00	930.00
IUUC-Mdo-062942	Monodelphis domestica	64.54	0.00e+00	922.00
IUUC-Mmu-064042	Mus musculus	89.84	0.00e+00	1349.00
IUUC-Mpu-066682	Mustela putorius furo	60.24	4.00e-132	464.00
IUUC-Mlu-068067	Myotis lucifugus	66.97	0.00e+00	977.00
IUUC-Nle-070108	Nomascus leucogenys	72.06	0.00e+00	1053.00
IUUC-Opr-070475	Ochotona princeps	64.32	0.00e+00	830.00
IUUC-Ont-072124	Oreochromis niloticus	51.26	5.00e-153	535.00
IUUC-Oan-073392	Ornithorhynchus anatinus	56.50	7.00e-62	231.00
IUUC-Ocu-074120	Oryctolagus cuniculus	69.24	0.00e+00	952.00
IUUC-Ola-087133	Oryzias latipes	49.92	8.00e-151	527.00
IUUC-Oga-088105	Otolemur garnettii	70.14	0.00e+00	1030.00
IUUC-Oar-089685	Ovis aries	58.84	5.00e-179	620.00
IUUC-Ptr-090971	Pan troglodytes	72.45	0.00e+00	1052.00
IUUC-Pan-092567	Papio anubis	71.61	0.00e+00	1036.00
IUUC-Psi-093775	Pelodiscus sinensis	62.11	0.00e+00	905.00
IUUC-Pma-094193	Petromyzon marinus	49.44	6.00e-46	178.00
IUUC-Pfo-096353	Poecilia formosa	45.55	2.00e-157	549.00
IUUC-Pab-097617	Pongo abelii	72.32	0.00e+00	1055.00
IUUC-Pva-102633	Pteropus vampyrus	68.67	0.00e+00	974.00
IUUC-Sha-107166	Sarcophilus harrisii	60.08	0.00e+00	816.00
IUUC-Sar-113012	Sorex araneus	64.39	0.00e+00	634.00
IUUC-Ssc-116285	Sus scrofa	67.92	0.00e+00	955.00
IUUC-Tgu-117060	Taeniopygia guttata	61.38	0.00e+00	887.00
IUUC-Tru-118102	Takifugu rubripes	51.46	2.00e-152	533.00
IUUC-Tni-120402	Tetraodon nigroviridis	51.52	3.00e-154	538.00
IUUC-Tbe-127463	Tupaia belangeri	60.95	1.00e-127	449.00
IUUC-Ttr-128785	Tursiops truncatus	68.97	0.00e+00	989.00
IUUC-Vpa-130467	Vicugna pacos	64.04	2.00e-177	615.00
IUUC-Xtr-131986	Xenopus tropicalis	51.39	1.00e-140	494.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence