iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-036758

Ensembl Protein ID

ENSFALP00000007911.1

UniProt Accession

U3JYQ7; U3JYQ7_FICAL

Genbank Protein ID

ENSFALP00000007911

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01000569

Gene Name

AMFR

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000007583.1	ENSFALT00000007944.1	ENSFALP00000007911.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	7.00e-09	35.8	246	284
UBD/Alpha-Helix/CUE	7.20e-11	41.5	418	455

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC+++++   + lpCgH+fh +Cl  w        +  +CP+Cr
   Q: 246  CAICWDSMQS-ARKLPCGHLFHNSCLRSW------LEQDTSCPTCR 284
           ********99.9*****************......9*********8 PP

UBD/Alpha-Helix/CUE

   S: 5    aleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           +++q++e+FP+++y ++ ++L ++t s+e +++n+Leg 
   Q: 418  MAHQIQEMFPQVPYHLVLQDL-QLTRSVEITTDNILEGR 455
           99*******************.***************95 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MLVAKLIQCM VFGPLRVSER QHLKDKFWNF IFYKFIFIFG VLNVQTVEEV VMWCLWFSGL 60
VFLHLMVQLC KDRFEYLSFS PTTPMSSHVR VLALLIAMLL SCCGLAVVCG VVGYTHGMHT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCTAGTGA ACACTGCCTG CTGTTTTCTG ATGCTGGTTG CTAAGCTAAT CCAGTGTATG 60
GTGTTTGGTC CTCTTCGTGT CAGTGAGAGG CAGGTGAGGC AGCAAACAAG GAAACGGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE
PS50089--ZF_RING_2

Pfam

PF02845--CUE
PF13639--zf-RING_2

SMART

SM00546--CUE
SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0005794--C:Golgi apparatus
GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0004872--F:receptor activity
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0032092--P:positive regulation of protein binding
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0051259--P:protein oligomerization
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000344	Aegilops tauschii	29.61	1.00e-23	103.00
IUUC-Aml-001300	Ailuropoda melanoleuca	79.80	0.00e+00	910.00
IUUC-Atr-002892	Amborella trichopoda	30.29	2.00e-31	130.00
IUUC-Apl-003404	Anas platyrhynchos	86.52	0.00e+00	952.00
IUUC-Aca-004559	Anolis carolinensis	82.47	0.00e+00	874.00
IUUC-Aly-006193	Arabidopsis lyrata	25.62	2.00e-26	113.00
IUUC-Ath-006702	Arabidopsis thaliana	31.80	1.00e-35	144.00
IUUC-Ago-007894	Ashbya gossypii	26.47	3.00e-12	66.60
IUUC-Ame-011640	Astyanax mexicanus	69.57	0.00e+00	733.00
IUUC-Bta-012980	Bos taurus	80.87	0.00e+00	941.00
IUUC-Bdi-014367	Brachypodium distachyon	31.90	9.00e-34	137.00
IUUC-Bol-015593	Brassica oleracea	31.58	1.00e-35	144.00
IUUC-Bra-017662	Brassica rapa	25.22	1.00e-26	114.00
IUUC-Cja-019577	Callithrix jacchus	80.87	0.00e+00	946.00
IUUC-Cfa-020793	Canis familiaris	79.77	0.00e+00	920.00
IUUC-Cpo-022387	Cavia porcellus	81.20	0.00e+00	915.00
IUUC-Csa-023168	Chlorocebus sabaeus	81.20	0.00e+00	951.00
IUUC-Cho-024433	Choloepus hoffmanni	80.88	0.00e+00	789.00
IUUC-Cin-025215	Ciona intestinalis	44.77	2.00e-131	462.00
IUUC-Csv-026133	Ciona savignyi	44.09	9.00e-121	427.00
IUUC-Cme-027285	Cyanidioschyzon merolae	30.08	1.00e-22	101.00
IUUC-Dre-027594	Danio rerio	68.56	0.00e+00	684.00
IUUC-Dno-029407	Dasypus novemcinctus	81.53	0.00e+00	918.00
IUUC-Dor-030961	Dipodomys ordii	81.53	0.00e+00	941.00
IUUC-Ete-032962	Echinops telfairi	93.48	8.00e-166	576.00
IUUC-Eca-033683	Equus caballus	79.40	0.00e+00	896.00
IUUC-Eeu-034515	Erinaceus europaeus	67.55	9.00e-69	254.00
IUUC-Fca-035398	Felis catus	82.64	0.00e+00	906.00
IUUC-Gmo-039014	Gadus morhua	66.67	0.00e+00	678.00
IUUC-Gga-040575	Gallus gallus	86.36	0.00e+00	1004.00
IUUC-Gac-041414	Gasterosteus aculeatus	65.54	0.00e+00	654.00
IUUC-Gma-043393	Glycine max	24.08	1.00e-30	127.00
IUUC-Hsa-046272	Homo sapiens	81.20	0.00e+00	952.00
IUUC-Hvu-047279	Hordeum vulgare	33.93	2.00e-35	142.00
IUUC-Itr-047956	Ictidomys tridecemlineatus	80.70	0.00e+00	912.00
IUUC-Lch-050491	Latimeria chalumnae	74.25	0.00e+00	789.00
IUUC-Loc-052758	Lepisosteus oculatus	72.44	0.00e+00	745.00
IUUC-Laf-053452	Loxodonta africana	81.03	0.00e+00	925.00
IUUC-Mcc-055820	Macaca mulatta	81.20	0.00e+00	948.00
IUUC-Meu-056726	Macropus eugenii	95.96	0.00e+00	633.00
IUUC-Mtr-058643	Medicago truncatula	25.38	6.00e-31	128.00
IUUC-Mga-059937	Meleagris gallopavo	86.02	0.00e+00	965.00
IUUC-Mmr-060730	Microcebus murinus	81.53	0.00e+00	916.00
IUUC-Mdo-062771	Monodelphis domestica	83.13	0.00e+00	939.00
IUUC-Mmu-064219	Mus musculus	80.72	0.00e+00	939.00
IUUC-Mac-065495	Musa acuminata	27.24	4.00e-28	119.00
IUUC-Mpu-066796	Mustela putorius furo	80.70	0.00e+00	935.00
IUUC-Mlu-068189	Myotis lucifugus	79.03	0.00e+00	881.00
IUUC-Nle-069239	Nomascus leucogenys	81.20	0.00e+00	950.00
IUUC-Opr-070702	Ochotona princeps	67.48	1.00e-121	429.00
IUUC-Ont-072033	Oreochromis niloticus	67.13	0.00e+00	722.00
IUUC-Oan-073717	Ornithorhynchus anatinus	75.13	0.00e+00	811.00
IUUC-Ocu-074145	Oryctolagus cuniculus	81.20	0.00e+00	946.00
IUUC-Oba-075221	Oryza barthii	32.29	7.00e-33	134.00
IUUC-Obr-076914	Oryza brachyantha	29.49	3.00e-33	135.00
IUUC-Ogl-077929	Oryza glaberrima	51.16	1.00e-11	62.40
IUUC-Ogu-078124	Oryza glumaepatula	32.29	7.00e-33	134.00
IUUC-Oin-080013	Oryza indica	32.29	1.00e-31	130.00
IUUC-Olo-080247	Oryza longistaminata	32.89	4.00e-29	122.00
IUUC-Ome-081769	Oryza meridionalis	32.88	5.00e-34	138.00
IUUC-Oni-082946	Oryza nivara	32.29	6.00e-33	134.00
IUUC-Opu-083268	Oryza punctata	30.85	2.00e-21	97.10
IUUC-Oru-085114	Oryza rufipogon	32.29	7.00e-33	134.00
IUUC-Osa-085829	Oryza sativa	32.88	7.00e-34	138.00
IUUC-Ola-087152	Oryzias latipes	65.23	0.00e+00	699.00
IUUC-Oga-088486	Otolemur garnettii	81.36	0.00e+00	919.00
IUUC-Oar-089310	Ovis aries	80.70	0.00e+00	939.00
IUUC-Ptr-090649	Pan troglodytes	81.20	0.00e+00	951.00
IUUC-Pan-091692	Papio anubis	77.20	0.00e+00	885.00
IUUC-Psi-093064	Pelodiscus sinensis	84.92	0.00e+00	768.00
IUUC-Pma-094763	Petromyzon marinus	78.21	1.00e-91	328.00
IUUC-Ppa-095969	Physcomitrella patens	29.62	1.00e-37	150.00
IUUC-Pfo-096810	Poecilia formosa	65.86	0.00e+00	702.00
IUUC-Pab-097859	Pongo abelii	81.03	0.00e+00	950.00
IUUC-Pop-099576	Populus trichocarpa	26.04	4.00e-33	135.00
IUUC-Pca-100344	Procavia capensis	80.27	0.00e+00	887.00
IUUC-Ppe-101829	Prunus persica	29.08	5.00e-34	139.00
IUUC-Pva-103114	Pteropus vampyrus	55.24	4.00e-154	538.00
IUUC-Rno-105880	Rattus norvegicus	79.24	0.00e+00	913.00
IUUC-Sce-106348	Saccharomyces cerevisiae	32.00	6.00e-09	55.50
IUUC-Sha-107015	Sarcophilus harrisii	82.82	0.00e+00	915.00
IUUC-Sja-107685	Schizosaccharomyces japonicus	27.95	3.00e-16	79.70
IUUC-Spo-108308	Schizosaccharomyces pombe	23.73	1.00e-18	88.20
IUUC-Smo-109664	Selaginella moellendorffii	31.03	5.00e-33	135.00
IUUC-Sit-110091	Setaria italica	32.03	6.00e-34	138.00
IUUC-Sly-111850	Solanum lycopersicum	26.27	1.00e-31	130.00
IUUC-Sar-113397	Sorex araneus	83.02	0.00e+00	718.00
IUUC-Sbi-114192	Sorghum bicolor	32.00	2.00e-34	140.00
IUUC-Ssc-115988	Sus scrofa	68.33	2.00e-122	431.00
IUUC-Tgu-116717	Taeniopygia guttata	90.17	0.00e+00	962.00
IUUC-Tru-117805	Takifugu rubripes	66.06	0.00e+00	732.00
IUUC-Tsy-119442	Tarsius syrichta	95.65	0.00e+00	636.00
IUUC-Tni-119777	Tetraodon nigroviridis	63.15	2.00e-168	585.00
IUUC-Tca-121783	Theobroma cacao	24.85	2.00e-30	127.00
IUUC-Tae-125239	Triticum aestivum	33.62	2.00e-36	146.00
IUUC-Tur-126538	Triticum urartu	30.22	2.00e-23	103.00
IUUC-Tbe-127322	Tupaia belangeri	64.91	2.00e-103	369.00
IUUC-Ttr-128181	Tursiops truncatus	80.87	0.00e+00	943.00
IUUC-Vpa-130483	Vicugna pacos	89.75	6.00e-159	553.00
IUUC-Xtr-132614	Xenopus tropicalis	72.65	0.00e+00	729.00
IUUC-Xma-133943	Xiphophorus maculatus	65.86	0.00e+00	698.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence