iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092372

Ensembl Protein ID

ENSPANP00000009967.1

UniProt Accession

A0A096NB50; A0A096NB50_PAPAN

Genbank Protein ID

ENSPANP00000009967

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01077030

Gene Name

RNF125

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000009802.1	ENSPANT00000028093.1	ENSPANP00000009967.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.80e-09	37.0	37	76
E3 activity/RING/U-box	1.50e-10	41.1	33	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           Ca+Cle + + p+ ++CgHvf+++C+   +      ++++++CP+Cr
   Q: 37   CAVCLEVLHQ-PVRTRCGHVFCRSCIaTSL------KNNKWTCPYCR 76
           ********99.777***********95555......**********8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawc 69
             f C++ le+ ++Pv + +G+++ rs+I+  l++++ tcP +r+ l +e +    + +r+ +++ 
   Q: 33   TSFDCAVCLEVLHQPVRTRCGHVFCRSCIATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEYK 98
           579******************************99999**********999999999999999986 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MGSVLSSDSG KSAPPSATPR ALQRRGDPEL PVTSFDCAVC LEVLHQPVRT RCGHVFCRSC 60
IATSLKNNKW TCPYCRAYLP SEGVPATDVA KRMKSEYKNC AECNTLVCLS EMRAHIRTCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGTCCG TGCTGAGCAG CGACAGCGGC AAATCGGCTC CCCCCTCTGC CACCCCGCGG 60
GCCCTGCAGC GCAGGGGGGA CCCGGAGTTG CCCGTCACGT CCTTCGACTG CGCCGTGTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008598--Di19_Zn_binding_dom
IPR034734--ZF_C2HC_RNF
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51803--ZF_C2HC_RNF
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF05605--zf-Di19

SMART

SM00184--RING

Gene Ontology

GO:0000139--C:Golgi membrane
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001992	Ailuropoda melanoleuca	91.38	2.00e-127	447.00
IUUC-Aca-004839	Anolis carolinensis	63.48	4.00e-67	246.00
IUUC-Bta-012827	Bos taurus	89.61	3.00e-124	437.00
IUUC-Cja-018794	Callithrix jacchus	93.97	4.00e-129	453.00
IUUC-Cfa-021234	Canis familiaris	90.52	1.00e-117	414.00
IUUC-Cpo-022412	Cavia porcellus	79.74	7.00e-107	379.00
IUUC-Csa-023406	Chlorocebus sabaeus	99.14	8.00e-136	475.00
IUUC-Cho-024427	Choloepus hoffmanni	76.27	1.00e-74	271.00
IUUC-Dno-030085	Dasypus novemcinctus	91.38	4.00e-126	443.00
IUUC-Dor-030911	Dipodomys ordii	70.26	4.00e-77	280.00
IUUC-Ete-032469	Echinops telfairi	86.64	1.00e-119	421.00
IUUC-Eca-034352	Equus caballus	92.67	3.00e-128	450.00
IUUC-Eeu-034889	Erinaceus europaeus	78.02	1.00e-102	365.00
IUUC-Fca-036116	Felis catus	91.81	2.00e-120	424.00
IUUC-Hsa-046518	Homo sapiens	96.12	5.00e-131	459.00
IUUC-Itr-048344	Ictidomys tridecemlineatus	94.92	7.00e-99	352.00
IUUC-Laf-053363	Loxodonta africana	91.03	1.00e-125	441.00
IUUC-Meu-056101	Macropus eugenii	78.67	1.00e-95	342.00
IUUC-Mdo-062046	Monodelphis domestica	75.11	2.00e-100	358.00
IUUC-Mmu-063184	Mus musculus	86.43	5.00e-60	222.00
IUUC-Mpu-065708	Mustela putorius furo	89.22	4.00e-124	436.00
IUUC-Mlu-067561	Myotis lucifugus	89.83	5.00e-94	336.00
IUUC-Nle-069665	Nomascus leucogenys	95.33	4.00e-120	423.00
IUUC-Opr-070301	Ochotona princeps	78.88	3.00e-105	374.00
IUUC-Ocu-074562	Oryctolagus cuniculus	92.06	2.00e-66	243.00
IUUC-Oga-088958	Otolemur garnettii	92.67	4.00e-128	449.00
IUUC-Oar-089541	Ovis aries	90.91	3.00e-95	340.00
IUUC-Ptr-090989	Pan troglodytes	96.55	5.00e-132	462.00
IUUC-Pab-098718	Pongo abelii	81.90	1.00e-105	375.00
IUUC-Pca-100453	Procavia capensis	89.66	4.00e-123	433.00
IUUC-Pva-102931	Pteropus vampyrus	91.81	4.00e-119	420.00
IUUC-Rno-105771	Rattus norvegicus	87.74	4.00e-101	360.00
IUUC-Sha-107557	Sarcophilus harrisii	75.54	2.00e-106	377.00
IUUC-Sar-113435	Sorex araneus	92.06	3.00e-66	243.00
IUUC-Ssc-116388	Sus scrofa	91.38	2.00e-127	447.00
IUUC-Tsy-119439	Tarsius syrichta	92.09	2.00e-96	344.00
IUUC-Tbe-127417	Tupaia belangeri	67.16	4.00e-70	256.00
IUUC-Ttr-129212	Tursiops truncatus	91.38	2.00e-127	447.00
IUUC-Vpa-130153	Vicugna pacos	89.22	7.00e-124	436.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence