iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000003729.3	ENSSSCT00000035939.1	ENSSSCP00000028585.1
ENSSSCG00000003729.3	ENSSSCT00000036393.1	ENSSSCP00000029315.1
ENSSSCG00000003729.3	ENSSSCT00000004129.2	ENSSSCP00000004036.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.50e-08	34.1	37	76
E3 activity/RING/U-box	2.40e-10	40.6	33	98

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C++Cle + + p+ ++CgHvf+++C+   +      ++++++CP+Cr
   Q: 37   CSVCLEVLHH-PVRTRCGHVFCRSCIaTSL------KNNKWTCPYCR 76
           ********99.777***********95555......**********8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawc 69
             f C++ le+ ++Pv + +G+++ rs+I+  l++++ tcP +r+ l +e +    + +r+ +++ 
   Q: 33   TSFDCSVCLEVLHHPVRTRCGHVFCRSCIATSLKNNKWTCPYCRAYLPSEGVPATDVAKRMKSEFQ 98
           579******************************99999*********9999999999999999885 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MGSVLSSDNG KSAPASATPR ALERRGDPAL PVTSFDCSVC LEVLHHPVRT RCGHVFCRSC 60
IATSLKNNKW TCPYCRAYLP SEGVPATDVA KRMKSEFQNC TECDTLVCLS EMRAHIRTCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCACTTGGCT GGAAGGTTCA CTGCCTTACC AGGTCCTCTG CTCTGCAGTT GAGGTGTCAG 60
GTTTCAATCC TCCCAGGGGC CCGGGACGTC GCAGCGTGCA ATGTGCGGCG GCCGCCTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008598--Di19_Zn_binding_dom
IPR034734--ZF_C2HC_RNF
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS51803--ZF_C2HC_RNF
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF05605--zf-Di19

SMART

SM00184--RING

Gene Ontology

GO:0000139--C:Golgi membrane
GO:0005622--C:intracellular
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ssc:100517591

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001992	Ailuropoda melanoleuca	93.97	2.00e-131	461.00
IUUC-Aca-004839	Anolis carolinensis	63.13	5.00e-68	249.00
IUUC-Bta-012827	Bos taurus	92.67	3.00e-129	453.00
IUUC-Cja-018794	Callithrix jacchus	93.10	1.00e-128	451.00
IUUC-Cfa-021234	Canis familiaris	93.10	2.00e-121	427.00
IUUC-Cpo-022412	Cavia porcellus	79.74	9.00e-107	379.00
IUUC-Csa-023406	Chlorocebus sabaeus	92.24	2.00e-128	450.00
IUUC-Cho-024427	Choloepus hoffmanni	76.27	2.00e-75	274.00
IUUC-Dno-030085	Dasypus novemcinctus	91.81	2.00e-127	447.00
IUUC-Dor-030911	Dipodomys ordii	69.83	7.00e-77	279.00
IUUC-Ete-032469	Echinops telfairi	85.34	2.00e-118	417.00
IUUC-Eca-034352	Equus caballus	94.40	8.00e-131	458.00
IUUC-Eeu-034889	Erinaceus europaeus	78.02	3.00e-102	363.00
IUUC-Fca-036116	Felis catus	93.53	2.00e-123	434.00
IUUC-Hsa-046518	Homo sapiens	91.81	4.00e-127	446.00
IUUC-Itr-048344	Ictidomys tridecemlineatus	96.61	1.00e-101	360.00
IUUC-Laf-053363	Loxodonta africana	91.88	2.00e-127	447.00
IUUC-Meu-056101	Macropus eugenii	78.20	1.00e-96	345.00
IUUC-Mdo-062046	Monodelphis domestica	75.11	8.00e-100	355.00
IUUC-Mmu-063184	Mus musculus	82.14	2.00e-57	214.00
IUUC-Mpu-065708	Mustela putorius furo	92.24	2.00e-128	451.00
IUUC-Mlu-067561	Myotis lucifugus	88.70	2.00e-94	337.00
IUUC-Nle-069665	Nomascus leucogenys	91.59	4.00e-117	413.00
IUUC-Opr-070301	Ochotona princeps	79.74	2.00e-106	377.00
IUUC-Ocu-074562	Oryctolagus cuniculus	92.86	2.00e-67	246.00
IUUC-Oga-088958	Otolemur garnettii	93.10	1.00e-129	454.00
IUUC-Oar-089541	Ovis aries	92.66	3.00e-98	350.00
IUUC-Ptr-090989	Pan troglodytes	92.24	4.00e-128	449.00
IUUC-Pan-092372	Papio anubis	91.38	2.00e-127	447.00
IUUC-Pab-098718	Pongo abelii	79.31	1.00e-103	367.00
IUUC-Pca-100453	Procavia capensis	90.52	6.00e-125	439.00
IUUC-Pva-102931	Pteropus vampyrus	92.67	2.00e-120	424.00
IUUC-Rno-105771	Rattus norvegicus	87.26	4.00e-101	360.00
IUUC-Sha-107557	Sarcophilus harrisii	75.54	7.00e-107	379.00
IUUC-Sar-113435	Sorex araneus	93.65	1.00e-68	250.00
IUUC-Tsy-119439	Tarsius syrichta	96.05	2.00e-100	357.00
IUUC-Tbe-127417	Tupaia belangeri	68.14	7.00e-72	262.00
IUUC-Ttr-129212	Tursiops truncatus	96.12	6.00e-134	469.00
IUUC-Vpa-130153	Vicugna pacos	93.10	4.00e-129	452.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence